ZSC31.H12INVITRO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZSC31.H12INVITRO.1.SM.B
Gene (human)	ZSCAN31 (GeneCards)
Gene synonyms (human)	ZNF310P, ZNF323
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	nRSRGGGMRRTKRKGhnn
GC content	60.03%
Information content (bits; total / per base)	13.024 / 0.724
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	8431

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.708	0.72	0.65	0.665	0.686	0.695	2.903	2.995	152.921	165.62

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.786	0.793	0.65	0.664	0.585	0.6
Overall, 2 experiments	best	0.877	0.881	0.702	0.718	0.615	0.634
Methyl HT-SELEX, 1 experiments	median	0.877	0.881	0.702	0.718	0.615	0.634
Methyl HT-SELEX, 1 experiments	best	0.877	0.881	0.702	0.718	0.615	0.634
Non-Methyl HT-SELEX, 1 experiments	median	0.695	0.706	0.598	0.61	0.555	0.566
Non-Methyl HT-SELEX, 1 experiments	best	0.695	0.706	0.598	0.61	0.555	0.566

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF24-like {2.3.3.10} (TFClass)
TFClass ID	TFClass: 2.3.3.10.7
HGNC	HGNC:14097
MGI
EntrezGene (human)	GeneID:64288 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZSC31_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96LW9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZSC31.H12INVITRO.1.SM.B.pcm
PWM	ZSC31.H12INVITRO.1.SM.B.pwm
PFM	ZSC31.H12INVITRO.1.SM.B.pfm
Alignment	ZSC31.H12INVITRO.1.SM.B.words.tsv
Threshold to P-value map	ZSC31.H12INVITRO.1.SM.B.thr
Motif in other formats
JASPAR format	ZSC31.H12INVITRO.1.SM.B_jaspar_format.txt
MEME format	ZSC31.H12INVITRO.1.SM.B_meme_format.meme
Transfac format	ZSC31.H12INVITRO.1.SM.B_transfac_format.txt
Homer format	ZSC31.H12INVITRO.1.SM.B_homer_format_0.001.txt ZSC31.H12INVITRO.1.SM.B_homer_format_0.0005.txt ZSC31.H12INVITRO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2520.75	1946.75	2087.75	1875.75
02	1018.25	686.25	5848.25	878.25
03	678.0	5666.0	1513.0	574.0
04	2395.0	113.0	5498.0	425.0
05	528.0	237.0	7306.0	360.0
06	318.0	330.0	7167.0	616.0
07	313.0	40.0	7943.0	135.0
08	883.0	6474.0	869.0	205.0
09	5417.0	317.0	2645.0	52.0
10	3397.0	75.0	4841.0	118.0
11	10.0	181.0	2238.0	6002.0
12	955.0	89.0	2195.0	5192.0
13	6552.0	640.0	1007.0	232.0
14	682.0	367.0	2595.0	4787.0
15	1147.0	303.0	6746.0	235.0
16	1511.0	3842.0	1291.0	1787.0
17	2468.75	1473.75	1785.75	2702.75
18	2112.0	1694.0	3051.0	1574.0

PFM

	A	C	G	T
01	0.299	0.231	0.248	0.222
02	0.121	0.081	0.694	0.104
03	0.08	0.672	0.179	0.068
04	0.284	0.013	0.652	0.05
05	0.063	0.028	0.867	0.043
06	0.038	0.039	0.85	0.073
07	0.037	0.005	0.942	0.016
08	0.105	0.768	0.103	0.024
09	0.643	0.038	0.314	0.006
10	0.403	0.009	0.574	0.014
11	0.001	0.021	0.265	0.712
12	0.113	0.011	0.26	0.616
13	0.777	0.076	0.119	0.028
14	0.081	0.044	0.308	0.568
15	0.136	0.036	0.8	0.028
16	0.179	0.456	0.153	0.212
17	0.293	0.175	0.212	0.321
18	0.251	0.201	0.362	0.187

PWM

	A	C	G	T
01	0.179	-0.079	-0.01	-0.116
02	-0.726	-1.12	1.02	-0.874
03	-1.132	0.988	-0.331	-1.298
04	0.128	-2.907	0.958	-1.597
05	-1.381	-2.177	1.242	-1.762
06	-1.885	-1.849	1.223	-1.228
07	-1.901	-3.911	1.326	-2.733
08	-0.869	1.121	-0.885	-2.32
09	0.943	-1.888	0.227	-3.661
10	0.477	-3.307	0.831	-2.865
11	-5.148	-2.444	0.06	1.046
12	-0.79	-3.141	0.041	0.901
13	1.133	-1.189	-0.737	-2.198
14	-1.126	-1.743	0.208	0.82
15	-0.608	-1.933	1.163	-2.185
16	-0.332	0.6	-0.49	-0.165
17	0.158	-0.357	-0.166	0.248
18	0.002	-0.218	0.37	-0.292

Standard thresholds

P-value	Threshold
0.001	3.88466
0.0005	4.87471
0.0001	6.94101