ZSC16.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZSC16.H12INVIVO.0.PSM.A
Gene (human)	ZSCAN16 (GeneCards)
Gene synonyms (human)	ZNF392, ZNF435
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	KGTKddCWGARCMYYh
GC content	49.72%
Information content (bits; total / per base)	13.496 / 0.844
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.874	0.922	0.816	0.873	0.878	0.924	4.612	4.835	222.953	314.328

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.712	0.741	0.573	0.613	0.523	0.558
Overall, 3 experiments	best	0.756	0.786	0.586	0.634	0.524	0.568
Methyl HT-SELEX, 1 experiments	median	0.712	0.741	0.573	0.613	0.523	0.558
Methyl HT-SELEX, 1 experiments	best	0.712	0.741	0.573	0.613	0.523	0.558
Non-Methyl HT-SELEX, 2 experiments	median	0.659	0.686	0.554	0.587	0.516	0.544
Non-Methyl HT-SELEX, 2 experiments	best	0.756	0.786	0.586	0.634	0.524	0.568

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.15
HGNC	HGNC:20813
MGI
EntrezGene (human)	GeneID:80345 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZSC16_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9H4T2 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	ZSC16.H12INVIVO.0.PSM.A.pcm
PWM	ZSC16.H12INVIVO.0.PSM.A.pwm
PFM	ZSC16.H12INVIVO.0.PSM.A.pfm
Alignment	ZSC16.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	ZSC16.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	ZSC16.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	ZSC16.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	ZSC16.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	ZSC16.H12INVIVO.0.PSM.A_homer_format_0.001.txt ZSC16.H12INVIVO.0.PSM.A_homer_format_0.0005.txt ZSC16.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	148.0	64.0	179.0	608.0
02	13.0	9.0	966.0	11.0
03	43.0	71.0	52.0	833.0
04	142.0	22.0	210.0	625.0
05	309.0	109.0	193.0	388.0
06	417.0	34.0	303.0	245.0
07	27.0	809.0	102.0	61.0
08	557.0	127.0	6.0	309.0
09	197.0	17.0	777.0	8.0
10	971.0	4.0	9.0	15.0
11	169.0	23.0	759.0	48.0
12	13.0	964.0	13.0	9.0
13	406.0	529.0	10.0	54.0
14	13.0	511.0	19.0	456.0
15	55.0	541.0	104.0	299.0
16	162.0	258.0	154.0	425.0

PFM

	A	C	G	T
01	0.148	0.064	0.179	0.609
02	0.013	0.009	0.967	0.011
03	0.043	0.071	0.052	0.834
04	0.142	0.022	0.21	0.626
05	0.309	0.109	0.193	0.388
06	0.417	0.034	0.303	0.245
07	0.027	0.81	0.102	0.061
08	0.558	0.127	0.006	0.309
09	0.197	0.017	0.778	0.008
10	0.972	0.004	0.009	0.015
11	0.169	0.023	0.76	0.048
12	0.013	0.965	0.013	0.009
13	0.406	0.53	0.01	0.054
14	0.013	0.512	0.019	0.456
15	0.055	0.542	0.104	0.299
16	0.162	0.258	0.154	0.425

PWM

	A	C	G	T
01	-0.519	-1.342	-0.33	0.886
02	-2.838	-3.155	1.348	-2.984
03	-1.727	-1.241	-1.543	1.2
04	-0.559	-2.361	-0.172	0.913
05	0.212	-0.82	-0.256	0.438
06	0.51	-1.951	0.192	-0.019
07	-2.17	1.171	-0.886	-1.389
08	0.798	-0.67	-3.483	0.212
09	-0.235	-2.597	1.13	-3.252
10	1.353	-3.782	-3.155	-2.71
11	-0.387	-2.319	1.107	-1.621
12	-2.838	1.346	-2.838	-3.155
13	0.483	0.747	-3.065	-1.507
14	-2.838	0.712	-2.496	0.599
15	-1.489	0.769	-0.866	0.179
16	-0.429	0.032	-0.479	0.529

Standard thresholds

P-value	Threshold
0.001	3.66011
0.0005	4.72096
0.0001	6.92731