ZSC16.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZSC16.H12INVITRO.0.PSM.A
Gene (human)	ZSCAN16 (GeneCards)
Gene synonyms (human)	ZNF392, ZNF435
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	19
Consensus	ndnYGTTAACWGARCACYb
GC content	43.8%
Information content (bits; total / per base)	21.61 / 1.137
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	2154

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.821	0.852	0.741	0.773	0.834	0.867	3.574	3.706	179.096	250.108

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.738	0.755	0.615	0.634	0.562	0.579
Overall, 3 experiments	best	0.779	0.798	0.632	0.657	0.569	0.592
Methyl HT-SELEX, 1 experiments	median	0.738	0.755	0.615	0.634	0.562	0.579
Methyl HT-SELEX, 1 experiments	best	0.738	0.755	0.615	0.634	0.562	0.579
Non-Methyl HT-SELEX, 2 experiments	median	0.688	0.703	0.592	0.607	0.552	0.564
Non-Methyl HT-SELEX, 2 experiments	best	0.779	0.798	0.632	0.657	0.569	0.592

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.15
HGNC	HGNC:20813
MGI
EntrezGene (human)	GeneID:80345 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZSC16_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q9H4T2 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	ZSC16.H12INVITRO.0.PSM.A.pcm
PWM	ZSC16.H12INVITRO.0.PSM.A.pwm
PFM	ZSC16.H12INVITRO.0.PSM.A.pfm
Alignment	ZSC16.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	ZSC16.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	ZSC16.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	ZSC16.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	ZSC16.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	ZSC16.H12INVITRO.0.PSM.A_homer_format_0.001.txt ZSC16.H12INVITRO.0.PSM.A_homer_format_0.0005.txt ZSC16.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	783.25	501.25	442.25	427.25
02	1199.75	296.75	304.75	352.75
03	663.0	343.0	650.0	498.0
04	93.0	303.0	61.0	1697.0
05	7.0	68.0	2079.0	0.0
06	2.0	58.0	1.0	2093.0
07	4.0	0.0	15.0	2135.0
08	1985.0	82.0	52.0	35.0
09	1974.0	72.0	30.0	78.0
10	2.0	2144.0	0.0	8.0
11	1596.0	180.0	4.0	374.0
12	125.0	71.0	1924.0	34.0
13	2045.0	92.0	6.0	11.0
14	822.0	127.0	1180.0	25.0
15	9.0	2141.0	1.0	3.0
16	1386.0	757.0	4.0	7.0
17	3.0	1431.0	1.0	719.0
18	49.0	1611.0	106.0	388.0
19	237.25	450.25	338.25	1128.25

PFM

	A	C	G	T
01	0.364	0.233	0.205	0.198
02	0.557	0.138	0.141	0.164
03	0.308	0.159	0.302	0.231
04	0.043	0.141	0.028	0.788
05	0.003	0.032	0.965	0.0
06	0.001	0.027	0.0	0.972
07	0.002	0.0	0.007	0.991
08	0.922	0.038	0.024	0.016
09	0.916	0.033	0.014	0.036
10	0.001	0.995	0.0	0.004
11	0.741	0.084	0.002	0.174
12	0.058	0.033	0.893	0.016
13	0.949	0.043	0.003	0.005
14	0.382	0.059	0.548	0.012
15	0.004	0.994	0.0	0.001
16	0.643	0.351	0.002	0.003
17	0.001	0.664	0.0	0.334
18	0.023	0.748	0.049	0.18
19	0.11	0.209	0.157	0.524

PWM

	A	C	G	T
01	0.374	-0.071	-0.196	-0.23
02	0.799	-0.593	-0.567	-0.421
03	0.207	-0.449	0.188	-0.078
04	-1.739	-0.572	-2.15	1.145
05	-4.104	-2.045	1.348	-5.641
06	-4.927	-2.199	-5.221	1.355
07	-4.514	-5.641	-3.464	1.375
08	1.302	-1.862	-2.305	-2.684
09	1.296	-1.989	-2.829	-1.911
10	-4.927	1.379	-5.641	-3.998
11	1.084	-1.089	-4.514	-0.363
12	-1.449	-2.003	1.271	-2.711
13	1.332	-1.75	-4.223	-3.734
14	0.422	-1.433	0.783	-3.0
15	-3.902	1.378	-5.221	-4.699
16	0.943	0.34	-4.514	-4.104
17	-4.699	0.975	-5.221	0.288
18	-2.362	1.093	-1.611	-0.326
19	-0.815	-0.178	-0.463	0.738

Standard thresholds

P-value	Threshold
0.001	-1.86179
0.0005	-0.17974
0.0001	3.36496