ZNF8.H12CORE.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZNF8.H12CORE.0.P.C
Gene (human)	ZNF8 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Znf8
Gene synonyms (mouse)	Zfp128
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	21
Consensus	vnvhvbGGTAYGnChhnSnnn
GC content	60.08%
Information content (bits; total / per base)	12.636 / 0.602
Data sources	ChIP-Seq
Aligned words	68

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (15)	0.809	0.927	0.721	0.882	0.794	0.945	2.662	5.216	44.42	258.886

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	Unclassified {2.3.4.0} (TFClass)
TFClass ID	TFClass: 2.3.4.0.29
HGNC	HGNC:13154
MGI	MGI:2389445
EntrezGene (human)	GeneID:7554 (SSTAR profile)
EntrezGene (mouse)	GeneID:243833 (SSTAR profile)
UniProt ID (human)	ZNF8_HUMAN
UniProt ID (mouse)	ZNF8_MOUSE
UniProt AC (human)	P17098 (TFClass)
UniProt AC (mouse)	Q8BGV5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	ZNF8.H12CORE.0.P.C.pcm
PWM	ZNF8.H12CORE.0.P.C.pwm
PFM	ZNF8.H12CORE.0.P.C.pfm
Alignment	ZNF8.H12CORE.0.P.C.words.tsv
Threshold to P-value map	ZNF8.H12CORE.0.P.C.thr
Motif in other formats
JASPAR format	ZNF8.H12CORE.0.P.C_jaspar_format.txt
MEME format	ZNF8.H12CORE.0.P.C_meme_format.meme
Transfac format	ZNF8.H12CORE.0.P.C_transfac_format.txt
Homer format	ZNF8.H12CORE.0.P.C_homer_format_0.001.txt ZNF8.H12CORE.0.P.C_homer_format_0.0005.txt ZNF8.H12CORE.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	12.0	23.0	28.0	5.0
02	17.0	27.0	17.0	7.0
03	17.0	30.0	13.0	8.0
04	12.0	16.0	10.0	30.0
05	15.0	20.0	28.0	5.0
06	4.0	17.0	11.0	36.0
07	0.0	0.0	67.0	1.0
08	0.0	0.0	68.0	0.0
09	0.0	12.0	1.0	55.0
10	65.0	0.0	3.0	0.0
11	6.0	48.0	5.0	9.0
12	3.0	1.0	63.0	1.0
13	7.0	33.0	7.0	21.0
14	2.0	60.0	3.0	3.0
15	18.0	16.0	9.0	25.0
16	29.0	13.0	10.0	16.0
17	9.0	19.0	22.0	18.0
18	4.0	14.0	39.0	11.0
19	25.0	16.0	11.0	16.0
20	18.0	19.0	20.0	11.0
21	15.0	23.0	16.0	14.0

PFM

	A	C	G	T
01	0.176	0.338	0.412	0.074
02	0.25	0.397	0.25	0.103
03	0.25	0.441	0.191	0.118
04	0.176	0.235	0.147	0.441
05	0.221	0.294	0.412	0.074
06	0.059	0.25	0.162	0.529
07	0.0	0.0	0.985	0.015
08	0.0	0.0	1.0	0.0
09	0.0	0.176	0.015	0.809
10	0.956	0.0	0.044	0.0
11	0.088	0.706	0.074	0.132
12	0.044	0.015	0.926	0.015
13	0.103	0.485	0.103	0.309
14	0.029	0.882	0.044	0.044
15	0.265	0.235	0.132	0.368
16	0.426	0.191	0.147	0.235
17	0.132	0.279	0.324	0.265
18	0.059	0.206	0.574	0.162
19	0.368	0.235	0.162	0.235
20	0.265	0.279	0.294	0.162
21	0.221	0.338	0.235	0.206

PWM

	A	C	G	T
01	-0.324	0.287	0.476	-1.093
02	0.0	0.441	0.0	-0.807
03	0.0	0.542	-0.25	-0.69
04	-0.324	-0.057	-0.491	0.542
05	-0.117	0.154	0.476	-1.093
06	-1.273	0.0	-0.404	0.719
07	-2.84	-2.84	1.327	-2.173
08	-2.84	-2.84	1.341	-2.84
09	-2.84	-0.324	-2.173	1.133
10	1.297	-2.84	-1.493	-2.84
11	-0.94	1.0	-1.093	-0.585
12	-1.493	-2.173	1.266	-2.173
13	-0.807	0.635	-0.807	0.2
14	-1.777	1.218	-1.493	-1.493
15	0.054	-0.057	-0.585	0.367
16	0.51	-0.25	-0.491	-0.057
17	-0.585	0.105	0.244	0.054
18	-1.273	-0.182	0.797	-0.404
19	0.367	-0.057	-0.404	-0.057
20	0.054	0.105	0.154	-0.404
21	-0.117	0.287	-0.057	-0.182

Standard thresholds

P-value	Threshold
0.001	4.47426
0.0005	5.35881
0.0001	7.19451