| Motif | ZNF76.H12RSNP.1.SM.B |
| Gene (human) | ZNF76 (GeneCards) |
| Gene synonyms (human) | D6S229E, ZNF523 |
| Gene (mouse) | Znf76 |
| Gene synonyms (mouse) | Zfp523 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | ZNF76.H12RSNP.1.SM.B |
| Gene (human) | ZNF76 (GeneCards) |
| Gene synonyms (human) | D6S229E, ZNF523 |
| Gene (mouse) | Znf76 |
| Gene synonyms (mouse) | Zfp523 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 20 |
| Consensus | nShRdKGCATTRTGGGWWdn |
| GC content | 48.21% |
| Information content (bits; total / per base) | 21.113 / 1.056 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 4388 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (12) | 0.862 | 0.889 | 0.792 | 0.838 | 0.889 | 0.903 | 4.186 | 4.375 | 142.422 | 229.699 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.948 | 0.946 | 0.763 | 0.777 | 0.641 | 0.668 |
| best | 0.955 | 0.954 | 0.768 | 0.782 | 0.644 | 0.672 | |
| Methyl HT-SELEX, 1 experiments | median | 0.955 | 0.954 | 0.768 | 0.782 | 0.644 | 0.672 |
| best | 0.955 | 0.954 | 0.768 | 0.782 | 0.644 | 0.672 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.941 | 0.938 | 0.759 | 0.771 | 0.637 | 0.664 |
| best | 0.941 | 0.938 | 0.759 | 0.771 | 0.637 | 0.664 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 12.872 | 2.839 | 0.228 | 0.107 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | More than 3 adjacent zinc fingers {2.3.3} (TFClass) |
| TF subfamily | ZNF76-like {2.3.3.28} (TFClass) |
| TFClass ID | TFClass: 2.3.3.28.1 |
| HGNC | HGNC:13149 |
| MGI | MGI:2687278 |
| EntrezGene (human) | GeneID:7629 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:224656 (SSTAR profile) |
| UniProt ID (human) | ZNF76_HUMAN |
| UniProt ID (mouse) | ZNF76_MOUSE |
| UniProt AC (human) | P36508 (TFClass) |
| UniProt AC (mouse) | Q8BMU0 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | ZNF76.H12RSNP.1.SM.B.pcm |
| PWM | ZNF76.H12RSNP.1.SM.B.pwm |
| PFM | ZNF76.H12RSNP.1.SM.B.pfm |
| Alignment | ZNF76.H12RSNP.1.SM.B.words.tsv |
| Threshold to P-value map | ZNF76.H12RSNP.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | ZNF76.H12RSNP.1.SM.B_jaspar_format.txt |
| MEME format | ZNF76.H12RSNP.1.SM.B_meme_format.meme |
| Transfac format | ZNF76.H12RSNP.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1010.0 | 1289.0 | 1032.0 | 1057.0 |
| 02 | 499.0 | 857.0 | 2794.0 | 238.0 |
| 03 | 747.0 | 1696.0 | 326.0 | 1619.0 |
| 04 | 1701.0 | 103.0 | 2392.0 | 192.0 |
| 05 | 1505.0 | 137.0 | 1935.0 | 811.0 |
| 06 | 331.0 | 8.0 | 774.0 | 3275.0 |
| 07 | 5.0 | 4.0 | 4370.0 | 9.0 |
| 08 | 235.0 | 3623.0 | 490.0 | 40.0 |
| 09 | 4227.0 | 23.0 | 121.0 | 17.0 |
| 10 | 14.0 | 31.0 | 95.0 | 4248.0 |
| 11 | 12.0 | 119.0 | 237.0 | 4020.0 |
| 12 | 2111.0 | 302.0 | 1929.0 | 46.0 |
| 13 | 42.0 | 13.0 | 6.0 | 4327.0 |
| 14 | 2.0 | 0.0 | 4385.0 | 1.0 |
| 15 | 0.0 | 1.0 | 4386.0 | 1.0 |
| 16 | 4.0 | 1.0 | 4369.0 | 14.0 |
| 17 | 1988.0 | 26.0 | 108.0 | 2266.0 |
| 18 | 2972.0 | 158.0 | 533.0 | 725.0 |
| 19 | 2198.75 | 300.75 | 1325.75 | 562.75 |
| 20 | 1145.25 | 602.25 | 1410.25 | 1230.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.23 | 0.294 | 0.235 | 0.241 |
| 02 | 0.114 | 0.195 | 0.637 | 0.054 |
| 03 | 0.17 | 0.387 | 0.074 | 0.369 |
| 04 | 0.388 | 0.023 | 0.545 | 0.044 |
| 05 | 0.343 | 0.031 | 0.441 | 0.185 |
| 06 | 0.075 | 0.002 | 0.176 | 0.746 |
| 07 | 0.001 | 0.001 | 0.996 | 0.002 |
| 08 | 0.054 | 0.826 | 0.112 | 0.009 |
| 09 | 0.963 | 0.005 | 0.028 | 0.004 |
| 10 | 0.003 | 0.007 | 0.022 | 0.968 |
| 11 | 0.003 | 0.027 | 0.054 | 0.916 |
| 12 | 0.481 | 0.069 | 0.44 | 0.01 |
| 13 | 0.01 | 0.003 | 0.001 | 0.986 |
| 14 | 0.0 | 0.0 | 0.999 | 0.0 |
| 15 | 0.0 | 0.0 | 1.0 | 0.0 |
| 16 | 0.001 | 0.0 | 0.996 | 0.003 |
| 17 | 0.453 | 0.006 | 0.025 | 0.516 |
| 18 | 0.677 | 0.036 | 0.121 | 0.165 |
| 19 | 0.501 | 0.069 | 0.302 | 0.128 |
| 20 | 0.261 | 0.137 | 0.321 | 0.28 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.082 | 0.161 | -0.061 | -0.037 |
| 02 | -0.785 | -0.246 | 0.934 | -1.521 |
| 03 | -0.383 | 0.435 | -1.209 | 0.389 |
| 04 | 0.438 | -2.347 | 0.779 | -1.734 |
| 05 | 0.316 | -2.067 | 0.567 | -0.301 |
| 06 | -1.194 | -4.69 | -0.348 | 1.092 |
| 07 | -5.043 | -5.195 | 1.381 | -4.596 |
| 08 | -1.534 | 1.193 | -0.804 | -3.262 |
| 09 | 1.347 | -3.78 | -2.189 | -4.053 |
| 10 | -4.224 | -3.503 | -2.427 | 1.352 |
| 11 | -4.356 | -2.206 | -1.525 | 1.297 |
| 12 | 0.654 | -1.285 | 0.564 | -3.129 |
| 13 | -3.216 | -4.288 | -4.911 | 1.371 |
| 14 | -5.592 | -6.262 | 1.384 | -5.872 |
| 15 | -6.262 | -5.872 | 1.384 | -5.872 |
| 16 | -5.195 | -5.872 | 1.381 | -4.224 |
| 17 | 0.594 | -3.667 | -2.301 | 0.724 |
| 18 | 0.995 | -1.926 | -0.72 | -0.413 |
| 19 | 0.694 | -1.289 | 0.189 | -0.666 |
| 20 | 0.043 | -0.598 | 0.251 | 0.114 |
| P-value | Threshold |
|---|---|
| 0.001 | -2.45664 |
| 0.0005 | -0.66559 |
| 0.0001 | 3.10126 |