ZNF12.H12CORE.2.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZNF12.H12CORE.2.S.C
Gene (human)	ZNF12 (GeneCards)
Gene synonyms (human)	GIOT3, KOX3, ZNF325
Gene (mouse)	Znf12
Gene synonyms (mouse)	Zfp12
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	C

Motif length	18
Consensus	nnTRWAACAARhRdbnMv
GC content	41.76%
Information content (bits; total / per base)	12.759 / 0.709
Data sources	HT-SELEX
Aligned words	9614

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (4)	0.783	0.79	0.75	0.757	0.796	0.8	3.718	3.729	111.819	152.022

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.952	0.949	0.748	0.77	0.62	0.657
Overall, 2 experiments	best	0.953	0.951	0.751	0.771	0.624	0.659
Methyl HT-SELEX, 1 experiments	median	0.953	0.951	0.745	0.769	0.616	0.656
Methyl HT-SELEX, 1 experiments	best	0.953	0.951	0.745	0.769	0.616	0.656
Non-Methyl HT-SELEX, 1 experiments	median	0.951	0.946	0.751	0.771	0.624	0.659
Non-Methyl HT-SELEX, 1 experiments	best	0.951	0.946	0.751	0.771	0.624	0.659

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF12-like {2.3.3.81} (TFClass)
TFClass ID	TFClass: 2.3.3.81.1
HGNC	HGNC:12902
MGI	MGI:99157
EntrezGene (human)	GeneID:7559 (SSTAR profile)
EntrezGene (mouse)	GeneID:231866 (SSTAR profile)
UniProt ID (human)	ZNF12_HUMAN
UniProt ID (mouse)	ZNF12_MOUSE
UniProt AC (human)	P17014 (TFClass)
UniProt AC (mouse)	Q7TSI0 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZNF12.H12CORE.2.S.C.pcm
PWM	ZNF12.H12CORE.2.S.C.pwm
PFM	ZNF12.H12CORE.2.S.C.pfm
Alignment	ZNF12.H12CORE.2.S.C.words.tsv
Threshold to P-value map	ZNF12.H12CORE.2.S.C.thr
Motif in other formats
JASPAR format	ZNF12.H12CORE.2.S.C_jaspar_format.txt
MEME format	ZNF12.H12CORE.2.S.C_meme_format.meme
Transfac format	ZNF12.H12CORE.2.S.C_transfac_format.txt
Homer format	ZNF12.H12CORE.2.S.C_homer_format_0.001.txt ZNF12.H12CORE.2.S.C_homer_format_0.0005.txt ZNF12.H12CORE.2.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1894.25	1951.25	3868.25	1900.25
02	1998.75	3865.75	1863.75	1885.75
03	510.0	462.0	857.0	7785.0
04	5642.0	219.0	3490.0	263.0
05	1737.0	732.0	264.0	6881.0
06	8729.0	28.0	801.0	56.0
07	9417.0	22.0	169.0	6.0
08	31.0	8806.0	741.0	36.0
09	7175.0	2.0	2421.0	16.0
10	8773.0	208.0	213.0	420.0
11	4897.0	1014.0	3532.0	171.0
12	3256.0	2312.0	1183.0	2863.0
13	6600.0	709.0	1895.0	410.0
14	2017.0	946.0	5076.0	1575.0
15	1173.0	2605.0	4488.0	1348.0
16	3271.0	3082.0	1544.0	1717.0
17	1358.25	6483.25	633.25	1139.25
18	2155.75	3887.75	1897.75	1672.75

PFM

	A	C	G	T
01	0.197	0.203	0.402	0.198
02	0.208	0.402	0.194	0.196
03	0.053	0.048	0.089	0.81
04	0.587	0.023	0.363	0.027
05	0.181	0.076	0.027	0.716
06	0.908	0.003	0.083	0.006
07	0.98	0.002	0.018	0.001
08	0.003	0.916	0.077	0.004
09	0.746	0.0	0.252	0.002
10	0.913	0.022	0.022	0.044
11	0.509	0.105	0.367	0.018
12	0.339	0.24	0.123	0.298
13	0.686	0.074	0.197	0.043
14	0.21	0.098	0.528	0.164
15	0.122	0.271	0.467	0.14
16	0.34	0.321	0.161	0.179
17	0.141	0.674	0.066	0.118
18	0.224	0.404	0.197	0.174

PWM

	A	C	G	T
01	-0.238	-0.208	0.476	-0.235
02	-0.184	0.475	-0.254	-0.242
03	-1.547	-1.645	-1.03	1.175
04	0.853	-2.386	0.373	-2.205
05	-0.324	-1.187	-2.201	1.051
06	1.289	-4.375	-1.097	-3.72
07	1.365	-4.595	-2.642	-5.67
08	-4.28	1.298	-1.175	-4.14
09	1.093	-6.329	0.007	-4.879
10	1.294	-2.437	-2.414	-1.74
11	0.711	-0.862	0.385	-2.631
12	0.303	-0.039	-0.708	0.175
13	1.01	-1.219	-0.237	-1.764
14	-0.175	-0.931	0.747	-0.422
15	-0.716	0.08	0.624	-0.578
16	0.308	0.248	-0.442	-0.336
17	-0.57	0.992	-1.331	-0.745
18	-0.109	0.481	-0.236	-0.362

Standard thresholds

P-value	Threshold
0.001	3.87916
0.0005	4.92901
0.0001	7.06446