ZN75A.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN75A.H12INVITRO.0.SM.B
Gene (human)	ZNF75A (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	bKTGGGAAARKbbdn
GC content	51.58%
Information content (bits; total / per base)	13.97 / 0.931
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9332

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.998	0.998	0.883	0.889	0.712	0.745
Overall, 3 experiments	best	1.0	1.0	0.952	0.955	0.771	0.801
Methyl HT-SELEX, 2 experiments	median	0.809	0.818	0.751	0.761	0.645	0.668
Methyl HT-SELEX, 2 experiments	best	1.0	1.0	0.952	0.955	0.771	0.801
Non-Methyl HT-SELEX, 1 experiments	median	0.998	0.998	0.883	0.889	0.712	0.745
Non-Methyl HT-SELEX, 1 experiments	best	0.998	0.998	0.883	0.889	0.712	0.745

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF75-like {2.3.3.6} (TFClass)
TFClass ID	TFClass: 2.3.3.6.1
HGNC	HGNC:13146
MGI
EntrezGene (human)	GeneID:7627 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN75A_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96N20 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	2

PCM	ZN75A.H12INVITRO.0.SM.B.pcm
PWM	ZN75A.H12INVITRO.0.SM.B.pwm
PFM	ZN75A.H12INVITRO.0.SM.B.pfm
Alignment	ZN75A.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	ZN75A.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	ZN75A.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	ZN75A.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	ZN75A.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	ZN75A.H12INVITRO.0.SM.B_homer_format_0.001.txt ZN75A.H12INVITRO.0.SM.B_homer_format_0.0005.txt ZN75A.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1110.0	1401.0	2070.0	4751.0
02	763.0	694.0	7102.0	773.0
03	306.0	134.0	143.0	8749.0
04	103.0	67.0	9114.0	48.0
05	72.0	99.0	8994.0	167.0
06	79.0	7.0	9229.0	17.0
07	8814.0	89.0	254.0	175.0
08	7830.0	160.0	862.0	480.0
09	8060.0	153.0	757.0	362.0
10	6896.0	293.0	1406.0	737.0
11	518.0	1339.0	5554.0	1921.0
12	1145.0	5385.0	1594.0	1208.0
13	1346.0	1525.0	3476.0	2985.0
14	1535.5	1302.5	3641.5	2852.5
15	1854.0	2139.0	3211.0	2128.0

PFM

	A	C	G	T
01	0.119	0.15	0.222	0.509
02	0.082	0.074	0.761	0.083
03	0.033	0.014	0.015	0.938
04	0.011	0.007	0.977	0.005
05	0.008	0.011	0.964	0.018
06	0.008	0.001	0.989	0.002
07	0.944	0.01	0.027	0.019
08	0.839	0.017	0.092	0.051
09	0.864	0.016	0.081	0.039
10	0.739	0.031	0.151	0.079
11	0.056	0.143	0.595	0.206
12	0.123	0.577	0.171	0.129
13	0.144	0.163	0.372	0.32
14	0.165	0.14	0.39	0.306
15	0.199	0.229	0.344	0.228

PWM

	A	C	G	T
01	-0.742	-0.509	-0.119	0.711
02	-1.116	-1.21	1.113	-1.103
03	-2.025	-2.841	-2.777	1.321
04	-3.099	-3.518	1.362	-3.838
05	-3.448	-3.138	1.349	-2.624
06	-3.358	-5.527	1.374	-4.797
07	1.328	-3.242	-2.21	-2.578
08	1.21	-2.667	-0.994	-1.577
09	1.239	-2.711	-1.124	-1.858
10	1.083	-2.068	-0.506	-1.15
11	-1.502	-0.555	0.867	-0.194
12	-0.711	0.836	-0.38	-0.657
13	-0.549	-0.425	0.398	0.246
14	-0.418	-0.582	0.445	0.201
15	-0.23	-0.087	0.319	-0.092

Standard thresholds

P-value	Threshold
0.001	3.32481
0.0005	4.44786
0.0001	6.78241