ZN740.H12INVITRO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN740.H12INVITRO.1.S.C
Gene (human)	ZNF740 (GeneCards)
Gene synonyms (human)	TB7
Gene (mouse)	Znf740
Gene synonyms (mouse)	Zfp740
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	20
Consensus	ddKKKKGGGGGGGGKGYKbd
GC content	75.38%
Information content (bits; total / per base)	20.889 / 1.044
Data sources	HT-SELEX
Aligned words	314

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.887	0.916	0.798	0.856	0.87	0.9	4.033	4.372	242.06	286.018

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.721	0.64	0.675	0.619	0.582	0.575
Non-Methyl HT-SELEX, 1 experiments	best	0.721	0.64	0.675	0.619	0.582	0.575

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Other with up to three adjacent zinc fingers {2.3.2} (TFClass)
TF subfamily	Other {2.3.2.4} (TFClass)
TFClass ID	TFClass: 2.3.2.4.5
HGNC	HGNC:27465
MGI	MGI:1915994
EntrezGene (human)	GeneID:283337 (SSTAR profile)
EntrezGene (mouse)	GeneID:68744 (SSTAR profile)
UniProt ID (human)	ZN740_HUMAN
UniProt ID (mouse)	ZN740_MOUSE
UniProt AC (human)	Q8NDX6 (TFClass)
UniProt AC (mouse)	Q6NZQ6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ZN740.H12INVITRO.1.S.C.pcm
PWM	ZN740.H12INVITRO.1.S.C.pwm
PFM	ZN740.H12INVITRO.1.S.C.pfm
Alignment	ZN740.H12INVITRO.1.S.C.words.tsv
Threshold to P-value map	ZN740.H12INVITRO.1.S.C.thr
Motif in other formats
JASPAR format	ZN740.H12INVITRO.1.S.C_jaspar_format.txt
MEME format	ZN740.H12INVITRO.1.S.C_meme_format.meme
Transfac format	ZN740.H12INVITRO.1.S.C_transfac_format.txt
Homer format	ZN740.H12INVITRO.1.S.C_homer_format_0.001.txt ZN740.H12INVITRO.1.S.C_homer_format_0.0005.txt ZN740.H12INVITRO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	59.75	37.75	165.75	50.75
02	54.0	27.0	181.0	52.0
03	39.0	25.0	193.0	57.0
04	30.0	18.0	182.0	84.0
05	18.0	14.0	193.0	89.0
06	8.0	2.0	213.0	91.0
07	1.0	1.0	240.0	72.0
08	0.0	2.0	271.0	41.0
09	0.0	2.0	296.0	16.0
10	1.0	1.0	309.0	3.0
11	0.0	0.0	314.0	0.0
12	1.0	0.0	307.0	6.0
13	1.0	0.0	307.0	6.0
14	0.0	1.0	312.0	1.0
15	7.0	4.0	79.0	224.0
16	7.0	0.0	306.0	1.0
17	28.0	201.0	3.0	82.0
18	64.0	9.0	172.0	69.0
19	45.75	57.75	117.75	92.75
20	67.5	40.5	129.5	76.5

PFM

	A	C	G	T
01	0.19	0.12	0.528	0.162
02	0.172	0.086	0.576	0.166
03	0.124	0.08	0.615	0.182
04	0.096	0.057	0.58	0.268
05	0.057	0.045	0.615	0.283
06	0.025	0.006	0.678	0.29
07	0.003	0.003	0.764	0.229
08	0.0	0.006	0.863	0.131
09	0.0	0.006	0.943	0.051
10	0.003	0.003	0.984	0.01
11	0.0	0.0	1.0	0.0
12	0.003	0.0	0.978	0.019
13	0.003	0.0	0.978	0.019
14	0.0	0.003	0.994	0.003
15	0.022	0.013	0.252	0.713
16	0.022	0.0	0.975	0.003
17	0.089	0.64	0.01	0.261
18	0.204	0.029	0.548	0.22
19	0.146	0.184	0.375	0.295
20	0.215	0.129	0.412	0.244

PWM

	A	C	G	T
01	-0.267	-0.713	0.738	-0.426
02	-0.366	-1.034	0.825	-0.403
03	-0.681	-1.106	0.889	-0.313
04	-0.933	-1.414	0.831	0.067
05	-1.414	-1.644	0.889	0.123
06	-2.137	-3.147	0.987	0.145
07	-3.49	-3.49	1.105	-0.085
08	-4.018	-3.147	1.226	-0.633
09	-4.018	-3.147	1.314	-1.523
10	-3.49	-3.49	1.357	-2.891
11	-4.018	-4.018	1.373	-4.018
12	-3.49	-4.018	1.35	-2.375
13	-3.49	-4.018	1.35	-2.375
14	-4.018	-3.49	1.366	-3.49
15	-2.249	-2.688	0.006	1.037
16	-2.249	-4.018	1.347	-3.49
17	-0.999	0.929	-2.891	0.043
18	-0.2	-2.036	0.775	-0.127
19	-0.527	-0.301	0.399	0.164
20	-0.148	-0.645	0.493	-0.025

Standard thresholds

P-value	Threshold
0.001	-0.09239
0.0005	1.38781
0.0001	4.52011