ZN740.H12CORE.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN740.H12CORE.1.S.C
Gene (human)	ZNF740 (GeneCards)
Gene synonyms (human)	TB7
Gene (mouse)	Znf740
Gene synonyms (mouse)	Zfp740
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	20
Consensus	ddKdKKKGGGGGGGKGYdbd
GC content	73.42%
Information content (bits; total / per base)	18.218 / 0.911
Data sources	HT-SELEX
Aligned words	732

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.891	0.921	0.801	0.862	0.873	0.901	4.068	4.406	239.119	275.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.716	0.636	0.672	0.616	0.581	0.573
Non-Methyl HT-SELEX, 1 experiments	best	0.716	0.636	0.672	0.616	0.581	0.573

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Other with up to three adjacent zinc fingers {2.3.2} (TFClass)
TF subfamily	Other {2.3.2.4} (TFClass)
TFClass ID	TFClass: 2.3.2.4.5
HGNC	HGNC:27465
MGI	MGI:1915994
EntrezGene (human)	GeneID:283337 (SSTAR profile)
EntrezGene (mouse)	GeneID:68744 (SSTAR profile)
UniProt ID (human)	ZN740_HUMAN
UniProt ID (mouse)	ZN740_MOUSE
UniProt AC (human)	Q8NDX6 (TFClass)
UniProt AC (mouse)	Q6NZQ6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ZN740.H12CORE.1.S.C.pcm
PWM	ZN740.H12CORE.1.S.C.pwm
PFM	ZN740.H12CORE.1.S.C.pfm
Alignment	ZN740.H12CORE.1.S.C.words.tsv
Threshold to P-value map	ZN740.H12CORE.1.S.C.thr
Motif in other formats
JASPAR format	ZN740.H12CORE.1.S.C_jaspar_format.txt
MEME format	ZN740.H12CORE.1.S.C_meme_format.meme
Transfac format	ZN740.H12CORE.1.S.C_transfac_format.txt
Homer format	ZN740.H12CORE.1.S.C_homer_format_0.001.txt ZN740.H12CORE.1.S.C_homer_format_0.0005.txt ZN740.H12CORE.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	140.5	100.5	356.5	134.5
02	131.0	73.0	400.0	128.0
03	86.0	61.0	438.0	147.0
04	92.0	54.0	363.0	223.0
05	66.0	35.0	414.0	217.0
06	28.0	26.0	455.0	223.0
07	9.0	9.0	504.0	210.0
08	4.0	21.0	587.0	120.0
09	1.0	7.0	671.0	53.0
10	1.0	1.0	721.0	9.0
11	3.0	1.0	726.0	2.0
12	5.0	3.0	703.0	21.0
13	10.0	2.0	671.0	49.0
14	3.0	10.0	714.0	5.0
15	48.0	36.0	187.0	461.0
16	40.0	0.0	678.0	14.0
17	92.0	419.0	17.0	204.0
18	133.0	34.0	405.0	160.0
19	107.0	120.0	315.0	190.0
20	142.0	110.0	301.0	179.0

PFM

	A	C	G	T
01	0.192	0.137	0.487	0.184
02	0.179	0.1	0.546	0.175
03	0.117	0.083	0.598	0.201
04	0.126	0.074	0.496	0.305
05	0.09	0.048	0.566	0.296
06	0.038	0.036	0.622	0.305
07	0.012	0.012	0.689	0.287
08	0.005	0.029	0.802	0.164
09	0.001	0.01	0.917	0.072
10	0.001	0.001	0.985	0.012
11	0.004	0.001	0.992	0.003
12	0.007	0.004	0.96	0.029
13	0.014	0.003	0.917	0.067
14	0.004	0.014	0.975	0.007
15	0.066	0.049	0.255	0.63
16	0.055	0.0	0.926	0.019
17	0.126	0.572	0.023	0.279
18	0.182	0.046	0.553	0.219
19	0.146	0.164	0.43	0.26
20	0.194	0.15	0.411	0.245

PWM

	A	C	G	T
01	-0.262	-0.592	0.662	-0.305
02	-0.331	-0.906	0.777	-0.354
03	-0.745	-1.081	0.868	-0.217
04	-0.679	-1.199	0.68	0.196
05	-1.004	-1.617	0.811	0.169
06	-1.829	-1.899	0.905	0.196
07	-2.853	-2.853	1.007	0.136
08	-3.487	-2.098	1.159	-0.417
09	-4.244	-3.061	1.293	-1.218
10	-4.244	-4.244	1.364	-2.853
11	-3.682	-4.244	1.371	-3.924
12	-3.324	-3.682	1.339	-2.098
13	-2.763	-3.924	1.293	-1.294
14	-3.682	-2.763	1.355	-3.324
15	-1.313	-1.59	0.021	0.919
16	-1.489	-4.718	1.303	-2.468
17	-0.679	0.823	-2.293	0.108
18	-0.316	-1.645	0.789	-0.133
19	-0.53	-0.417	0.539	0.037
20	-0.251	-0.503	0.494	-0.022

Standard thresholds

P-value	Threshold
0.001	1.35566
0.0005	2.70376
0.0001	5.54036