ZN580.H12CORE.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN580.H12CORE.1.SM.B
Gene (human)	ZNF580 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Znf580
Gene synonyms (mouse)	Zfp580
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	17
Consensus	hhhhhhhnvCTACChYn
GC content	53.31%
Information content (bits; total / per base)	12.424 / 0.731
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	8983

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.932	0.894	0.884	0.842	0.78	0.759
Overall, 2 experiments	best	0.941	0.907	0.896	0.857	0.798	0.775
Methyl HT-SELEX, 1 experiments	median	0.941	0.907	0.896	0.857	0.798	0.775
Methyl HT-SELEX, 1 experiments	best	0.941	0.907	0.896	0.857	0.798	0.775
Non-Methyl HT-SELEX, 1 experiments	median	0.924	0.881	0.871	0.827	0.762	0.742
Non-Methyl HT-SELEX, 1 experiments	best	0.924	0.881	0.871	0.827	0.762	0.742

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Other with up to three adjacent zinc fingers {2.3.2} (TFClass)
TF subfamily	Other {2.3.2.4} (TFClass)
TFClass ID	TFClass: 2.3.2.4.3
HGNC	HGNC:29473
MGI	MGI:1916242
EntrezGene (human)	GeneID:51157 (SSTAR profile)
EntrezGene (mouse)	GeneID:68992 (SSTAR profile)
UniProt ID (human)	ZN580_HUMAN
UniProt ID (mouse)	ZN580_MOUSE
UniProt AC (human)	Q9UK33 (TFClass)
UniProt AC (mouse)	Q9DB38 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN580.H12CORE.1.SM.B.pcm
PWM	ZN580.H12CORE.1.SM.B.pwm
PFM	ZN580.H12CORE.1.SM.B.pfm
Alignment	ZN580.H12CORE.1.SM.B.words.tsv
Threshold to P-value map	ZN580.H12CORE.1.SM.B.thr
Motif in other formats
JASPAR format	ZN580.H12CORE.1.SM.B_jaspar_format.txt
MEME format	ZN580.H12CORE.1.SM.B_meme_format.meme
Transfac format	ZN580.H12CORE.1.SM.B_transfac_format.txt
Homer format	ZN580.H12CORE.1.SM.B_homer_format_0.001.txt ZN580.H12CORE.1.SM.B_homer_format_0.0005.txt ZN580.H12CORE.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2489.75	2940.75	994.75	2557.75
02	2742.25	3408.25	689.25	2143.25
03	2447.0	4240.0	551.0	1745.0
04	1966.0	4833.0	675.0	1509.0
05	1693.0	4683.0	753.0	1854.0
06	1869.0	3813.0	927.0	2374.0
07	1891.0	3064.0	902.0	3126.0
08	2740.0	2243.0	1805.0	2195.0
09	2351.0	4592.0	1632.0	408.0
10	228.0	8521.0	4.0	230.0
11	3.0	0.0	0.0	8980.0
12	8983.0	0.0	0.0	0.0
13	0.0	8983.0	0.0	0.0
14	0.0	8983.0	0.0	0.0
15	1517.0	4864.0	497.0	2105.0
16	999.0	1658.0	440.0	5886.0
17	2163.0	2876.0	1831.0	2113.0

PFM

	A	C	G	T
01	0.277	0.327	0.111	0.285
02	0.305	0.379	0.077	0.239
03	0.272	0.472	0.061	0.194
04	0.219	0.538	0.075	0.168
05	0.188	0.521	0.084	0.206
06	0.208	0.424	0.103	0.264
07	0.211	0.341	0.1	0.348
08	0.305	0.25	0.201	0.244
09	0.262	0.511	0.182	0.045
10	0.025	0.949	0.0	0.026
11	0.0	0.0	0.0	1.0
12	1.0	0.0	0.0	0.0
13	0.0	1.0	0.0	0.0
14	0.0	1.0	0.0	0.0
15	0.169	0.541	0.055	0.234
16	0.111	0.185	0.049	0.655
17	0.241	0.32	0.204	0.235

PWM

	A	C	G	T
01	0.103	0.269	-0.813	0.13
02	0.2	0.417	-1.179	-0.047
03	0.086	0.635	-1.402	-0.252
04	-0.133	0.766	-1.2	-0.397
05	-0.282	0.734	-1.091	-0.191
06	-0.183	0.529	-0.883	0.055
07	-0.172	0.31	-0.911	0.33
08	0.199	-0.001	-0.218	-0.023
09	0.046	0.715	-0.319	-1.701
10	-2.279	1.333	-5.881	-2.27
11	-6.055	-6.895	-6.895	1.385
12	1.386	-6.895	-6.895	-6.895
13	-6.895	1.386	-6.895	-6.895
14	-6.895	1.386	-6.895	-6.895
15	-0.392	0.772	-1.505	-0.065
16	-0.809	-0.303	-1.626	0.963
17	-0.038	0.247	-0.204	-0.061

Standard thresholds

P-value	Threshold
0.001	3.37986
0.0005	4.99866
0.0001	7.48731