MotifZN454.H12INVIVO.1.SM.B
Gene (human)ZNF454
(GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusvvSSMYGGCGCCWn
GC content76.43%
Information content (bits; total / per base)13.803 / 0.986
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2411

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (7) 0.5 0.575 0.319 0.367 0.343 0.62 0.755 1.771 12.076 14.149

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.893 0.895 0.813 0.824 0.772 0.783
best 1.0 1.0 0.997 0.996 0.983 0.979
Methyl HT-SELEX, 1 experiments median 0.787 0.791 0.63 0.653 0.561 0.587
best 0.787 0.791 0.63 0.653 0.561 0.587
Non-Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.997 0.996 0.983 0.979
best 1.0 1.0 0.997 0.996 0.983 0.979
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyUnclassified {2.3.3.0} (TFClass)
TFClass IDTFClass: 2.3.3.0.125
HGNCHGNC:21200
MGI
EntrezGene (human)GeneID:285676
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)ZN454_HUMAN
UniProt ID (mouse)
UniProt AC (human)Q8N9F8
(TFClass)
UniProt AC (mouse)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01817.0404.0923.0267.0
02534.75460.751165.75249.75
03253.01539.0397.0222.0
04206.0626.01469.0110.0
05423.01736.0172.080.0
06126.01590.022.0673.0
0754.065.02275.017.0
0826.016.02352.017.0
092.02409.00.00.0
109.06.02396.00.0
112.02392.01.016.0
1238.01806.022.0545.0
131379.75344.7592.75593.75
14756.0635.0480.0540.0
PFM
ACGT
010.3390.1680.3830.111
020.2220.1910.4840.104
030.1050.6380.1650.092
040.0850.260.6090.046
050.1750.720.0710.033
060.0520.6590.0090.279
070.0220.0270.9440.007
080.0110.0070.9760.007
090.0010.9990.00.0
100.0040.0020.9940.0
110.0010.9920.00.007
120.0160.7490.0090.226
130.5720.1430.0380.246
140.3140.2630.1990.224
PWM
ACGT
010.303-0.3990.425-0.81
02-0.119-0.2680.658-0.877
03-0.8640.935-0.416-0.993
04-1.0670.0380.889-1.687
05-0.3531.056-1.246-1.999
06-1.5530.968-3.2290.11
07-2.38-2.2011.326-3.463
08-3.074-3.5171.359-3.463
09-5.0321.383-5.738-5.738
10-4.012-4.3321.378-5.738
11-5.0321.376-5.324-3.517
12-2.7171.095-3.229-0.1
130.826-0.556-1.854-0.015
140.2260.052-0.227-0.11
Standard thresholds
P-value Threshold
0.001 3.05576
0.0005 4.31631
0.0001 6.91756