ZN454.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN454.H12INVITRO.0.P.B
Gene (human)	ZNF454 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	23
Consensus	CYvhYdGRdSMYRRWKCYWTTYb
GC content	53.46%
Information content (bits; total / per base)	17.377 / 0.756
Data sources	ChIP-Seq
Aligned words	71

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (7)	0.68	0.815	0.541	0.794	0.834	0.842	5.539	6.052	31.959	81.125

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.543	0.531	0.526	0.521	0.512	0.512
Overall, 2 experiments	best	0.627	0.582	0.587	0.56	0.552	0.541
Methyl HT-SELEX, 1 experiments	median	0.46	0.479	0.465	0.481	0.471	0.484
Methyl HT-SELEX, 1 experiments	best	0.46	0.479	0.465	0.481	0.471	0.484
Non-Methyl HT-SELEX, 1 experiments	median	0.627	0.582	0.587	0.56	0.552	0.541
Non-Methyl HT-SELEX, 1 experiments	best	0.627	0.582	0.587	0.56	0.552	0.541

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.125
HGNC	HGNC:21200
MGI
EntrezGene (human)	GeneID:285676 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN454_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8N9F8 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN454.H12INVITRO.0.P.B.pcm
PWM	ZN454.H12INVITRO.0.P.B.pwm
PFM	ZN454.H12INVITRO.0.P.B.pfm
Alignment	ZN454.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	ZN454.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	ZN454.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	ZN454.H12INVITRO.0.P.B_meme_format.meme
Transfac format	ZN454.H12INVITRO.0.P.B_transfac_format.txt
Homer format	ZN454.H12INVITRO.0.P.B_homer_format_0.001.txt ZN454.H12INVITRO.0.P.B_homer_format_0.0005.txt ZN454.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	5.0	57.0	1.0	8.0
02	5.0	49.0	4.0	13.0
03	37.0	20.0	8.0	6.0
04	9.0	9.0	3.0	50.0
05	5.0	48.0	1.0	17.0
06	17.0	9.0	14.0	31.0
07	0.0	9.0	60.0	2.0
08	13.0	1.0	48.0	9.0
09	11.0	6.0	41.0	13.0
10	1.0	47.0	22.0	1.0
11	19.0	44.0	0.0	8.0
12	2.0	14.0	5.0	50.0
13	15.0	2.0	47.0	7.0
14	23.0	2.0	45.0	1.0
15	30.0	2.0	6.0	33.0
16	3.0	1.0	40.0	27.0
17	6.0	58.0	3.0	4.0
18	1.0	50.0	3.0	17.0
19	29.0	1.0	2.0	39.0
20	3.0	1.0	1.0	66.0
21	2.0	13.0	0.0	56.0
22	0.0	22.0	6.0	43.0
23	5.0	21.0	27.0	18.0

PFM

	A	C	G	T
01	0.07	0.803	0.014	0.113
02	0.07	0.69	0.056	0.183
03	0.521	0.282	0.113	0.085
04	0.127	0.127	0.042	0.704
05	0.07	0.676	0.014	0.239
06	0.239	0.127	0.197	0.437
07	0.0	0.127	0.845	0.028
08	0.183	0.014	0.676	0.127
09	0.155	0.085	0.577	0.183
10	0.014	0.662	0.31	0.014
11	0.268	0.62	0.0	0.113
12	0.028	0.197	0.07	0.704
13	0.211	0.028	0.662	0.099
14	0.324	0.028	0.634	0.014
15	0.423	0.028	0.085	0.465
16	0.042	0.014	0.563	0.38
17	0.085	0.817	0.042	0.056
18	0.014	0.704	0.042	0.239
19	0.408	0.014	0.028	0.549
20	0.042	0.014	0.014	0.93
21	0.028	0.183	0.0	0.789
22	0.0	0.31	0.085	0.606
23	0.07	0.296	0.38	0.254

PWM

	A	C	G	T
01	-1.132	1.127	-2.209	-0.73
02	-1.132	0.979	-1.312	-0.291
03	0.705	0.113	-0.73	-0.979
04	-0.626	-0.626	-1.532	0.998
05	-1.132	0.958	-2.209	-0.041
06	-0.041	-0.626	-0.222	0.533
07	-2.871	-0.626	1.177	-1.814
08	-0.291	-2.209	0.958	-0.626
09	-0.444	-0.979	0.805	-0.291
10	-2.209	0.938	0.204	-2.209
11	0.064	0.873	-2.871	-0.73
12	-1.814	-0.222	-1.132	0.998
13	-0.158	-1.814	0.938	-0.847
14	0.246	-1.814	0.895	-2.209
15	0.501	-1.814	-0.979	0.594
16	-1.532	-2.209	0.78	0.4
17	-0.979	1.144	-1.532	-1.312
18	-2.209	0.998	-1.532	-0.041
19	0.469	-2.209	-1.814	0.756
20	-1.532	-2.209	-2.209	1.271
21	-1.814	-0.291	-2.871	1.11
22	-2.871	0.204	-0.979	0.851
23	-1.132	0.159	0.4	0.013

Standard thresholds

P-value	Threshold
0.001	3.32276
0.0005	4.35676
0.0001	6.54831