ZN449.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN449.H12INVIVO.0.P.B
Gene (human)	ZNF449 (GeneCards)
Gene synonyms (human)	ZSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	nKGTTGGGCKb
GC content	66.21%
Information content (bits; total / per base)	13.54 / 1.231
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.906	0.946	0.85	0.893	0.899	0.943	4.024	4.299	406.518	477.194

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.744	0.72	0.615	0.621	0.548	0.568
Non-Methyl HT-SELEX, 1 experiments	best	0.744	0.72	0.615	0.621	0.548	0.568

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	5.82	2.39	0.219	0.156

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.41
HGNC	HGNC:21039
MGI
EntrezGene (human)	GeneID:203523 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN449_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q6P9G9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ZN449.H12INVIVO.0.P.B.pcm
PWM	ZN449.H12INVIVO.0.P.B.pwm
PFM	ZN449.H12INVIVO.0.P.B.pfm
Alignment	ZN449.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	ZN449.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	ZN449.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	ZN449.H12INVIVO.0.P.B_meme_format.meme
Transfac format	ZN449.H12INVIVO.0.P.B_transfac_format.txt
Homer format	ZN449.H12INVIVO.0.P.B_homer_format_0.001.txt ZN449.H12INVIVO.0.P.B_homer_format_0.0005.txt ZN449.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	163.0	209.0	255.0	373.0
02	95.0	22.0	766.0	117.0
03	3.0	11.0	966.0	20.0
04	4.0	263.0	6.0	727.0
05	53.0	17.0	29.0	901.0
06	2.0	1.0	992.0	5.0
07	1.0	1.0	992.0	6.0
08	7.0	83.0	899.0	11.0
09	1.0	994.0	3.0	2.0
10	83.0	19.0	181.0	717.0
11	20.0	292.0	282.0	406.0

PFM

	A	C	G	T
01	0.163	0.209	0.255	0.373
02	0.095	0.022	0.766	0.117
03	0.003	0.011	0.966	0.02
04	0.004	0.263	0.006	0.727
05	0.053	0.017	0.029	0.901
06	0.002	0.001	0.992	0.005
07	0.001	0.001	0.992	0.006
08	0.007	0.083	0.899	0.011
09	0.001	0.994	0.003	0.002
10	0.083	0.019	0.181	0.717
11	0.02	0.292	0.282	0.406

PWM

	A	C	G	T
01	-0.424	-0.178	0.02	0.398
02	-0.956	-2.362	1.115	-0.752
03	-3.975	-2.985	1.347	-2.45
04	-3.783	0.05	-3.484	1.063
05	-1.526	-2.598	-2.103	1.277
06	-4.213	-4.525	1.373	-3.622
07	-4.525	-4.525	1.373	-3.484
08	-3.362	-1.089	1.275	-2.985
09	-4.525	1.375	-3.975	-4.213
10	-1.089	-2.497	-0.32	1.049
11	-2.45	0.154	0.12	0.482

Standard thresholds

P-value	Threshold
0.001	3.275835
0.0005	4.48808
0.0001	6.94585