ZN449.H12INVITRO.1.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN449.H12INVITRO.1.S.C
Gene (human)	ZNF449 (GeneCards)
Gene synonyms (human)	ZSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	15
Consensus	dddRGKWGGKMGbKn
GC content	64.97%
Information content (bits; total / per base)	10.222 / 0.681
Data sources	HT-SELEX
Aligned words	6585

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.658	0.684	0.454	0.481	0.694	0.737	1.946	2.189	65.204	93.0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.714	0.654	0.66	0.617	0.609	0.585
Non-Methyl HT-SELEX, 1 experiments	best	0.714	0.654	0.66	0.617	0.609	0.585

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.844	0.939	0.067	0.04

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.41
HGNC	HGNC:21039
MGI
EntrezGene (human)	GeneID:203523 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN449_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q6P9G9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ZN449.H12INVITRO.1.S.C.pcm
PWM	ZN449.H12INVITRO.1.S.C.pwm
PFM	ZN449.H12INVITRO.1.S.C.pfm
Alignment	ZN449.H12INVITRO.1.S.C.words.tsv
Threshold to P-value map	ZN449.H12INVITRO.1.S.C.thr
Motif in other formats
JASPAR format	ZN449.H12INVITRO.1.S.C_jaspar_format.txt
MEME format	ZN449.H12INVITRO.1.S.C_meme_format.meme
Transfac format	ZN449.H12INVITRO.1.S.C_transfac_format.txt
Homer format	ZN449.H12INVITRO.1.S.C_homer_format_0.001.txt ZN449.H12INVITRO.1.S.C_homer_format_0.0005.txt ZN449.H12INVITRO.1.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1335.75	1040.75	2859.75	1348.75
02	2090.75	616.75	2636.75	1240.75
03	2306.0	568.0	2066.0	1645.0
04	693.0	579.0	4735.0	578.0
05	199.0	705.0	5288.0	393.0
06	768.0	24.0	2756.0	3037.0
07	2002.0	1.0	145.0	4437.0
08	0.0	1.0	6584.0	0.0
09	2.0	950.0	5582.0	51.0
10	466.0	40.0	3959.0	2120.0
11	1044.0	4286.0	888.0	367.0
12	1067.0	0.0	5212.0	306.0
13	659.0	2205.0	1844.0	1877.0
14	673.25	405.25	4593.25	913.25
15	1614.5	1104.5	2500.5	1365.5

PFM

	A	C	G	T
01	0.203	0.158	0.434	0.205
02	0.318	0.094	0.4	0.188
03	0.35	0.086	0.314	0.25
04	0.105	0.088	0.719	0.088
05	0.03	0.107	0.803	0.06
06	0.117	0.004	0.419	0.461
07	0.304	0.0	0.022	0.674
08	0.0	0.0	1.0	0.0
09	0.0	0.144	0.848	0.008
10	0.071	0.006	0.601	0.322
11	0.159	0.651	0.135	0.056
12	0.162	0.0	0.791	0.046
13	0.1	0.335	0.28	0.285
14	0.102	0.062	0.698	0.139
15	0.245	0.168	0.38	0.207

PWM

	A	C	G	T
01	-0.209	-0.458	0.552	-0.199
02	0.239	-0.98	0.471	-0.282
03	0.337	-1.062	0.227	-0.001
04	-0.863	-1.042	1.056	-1.044
05	-2.103	-0.846	1.166	-1.428
06	-0.761	-4.142	0.515	0.612
07	0.195	-6.245	-2.416	0.991
08	-6.62	-6.245	1.385	-6.62
09	-5.973	-0.549	1.22	-3.434
10	-1.259	-3.665	0.877	0.253
11	-0.455	0.956	-0.616	-1.496
12	-0.433	-6.62	1.152	-1.677
13	-0.914	0.292	0.113	0.131
14	-0.892	-1.398	1.025	-0.588
15	-0.019	-0.398	0.418	-0.187

Standard thresholds

P-value	Threshold
0.001	4.77031
0.0005	5.61881
0.0001	7.29366