ZN449.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN449.H12CORE.0.P.B
Gene (human)	ZNF449 (GeneCards)
Gene synonyms (human)	ZSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	KGTTGGGCKb
GC content	68.09%
Information content (bits; total / per base)	13.473 / 1.347
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (12)	0.905	0.944	0.847	0.89	0.898	0.942	3.864	4.13	404.696	478.824

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.749	0.724	0.622	0.626	0.553	0.571
Non-Methyl HT-SELEX, 1 experiments	best	0.749	0.724	0.622	0.626	0.553	0.571

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	9.669	3.272	0.223	0.157

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.41
HGNC	HGNC:21039
MGI
EntrezGene (human)	GeneID:203523 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN449_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q6P9G9 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0

PCM	ZN449.H12CORE.0.P.B.pcm
PWM	ZN449.H12CORE.0.P.B.pwm
PFM	ZN449.H12CORE.0.P.B.pfm
Alignment	ZN449.H12CORE.0.P.B.words.tsv
Threshold to P-value map	ZN449.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	ZN449.H12CORE.0.P.B_jaspar_format.txt
MEME format	ZN449.H12CORE.0.P.B_meme_format.meme
Transfac format	ZN449.H12CORE.0.P.B_transfac_format.txt
Homer format	ZN449.H12CORE.0.P.B_homer_format_0.001.txt ZN449.H12CORE.0.P.B_homer_format_0.0005.txt ZN449.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	97.0	22.0	764.0	117.0
02	4.0	15.0	958.0	23.0
03	5.0	260.0	5.0	730.0
04	52.0	16.0	22.0	910.0
05	1.0	1.0	996.0	2.0
06	0.0	2.0	991.0	7.0
07	9.0	88.0	891.0	12.0
08	0.0	996.0	2.0	2.0
09	90.0	12.0	187.0	711.0
10	22.0	300.0	281.0	397.0

PFM

	A	C	G	T
01	0.097	0.022	0.764	0.117
02	0.004	0.015	0.958	0.023
03	0.005	0.26	0.005	0.73
04	0.052	0.016	0.022	0.91
05	0.001	0.001	0.996	0.002
06	0.0	0.002	0.991	0.007
07	0.009	0.088	0.891	0.012
08	0.0	0.996	0.002	0.002
09	0.09	0.012	0.187	0.711
10	0.022	0.3	0.281	0.397

PWM

	A	C	G	T
01	-0.936	-2.362	1.112	-0.752
02	-3.783	-2.711	1.338	-2.32
03	-3.622	0.039	-3.622	1.067
04	-1.544	-2.653	-2.362	1.287
05	-4.525	-4.525	1.377	-4.213
06	-4.982	-4.213	1.372	-3.362
07	-3.156	-1.032	1.266	-2.909
08	-4.982	1.377	-4.213	-4.213
09	-1.01	-2.909	-0.288	1.041
10	-2.362	0.181	0.116	0.46

Standard thresholds

P-value	Threshold
0.001	3.27306
0.0005	4.50741
0.0001	7.007865