ZN410.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN410.H12INVIVO.0.SM.D
Gene (human)	ZNF410 (GeneCards)
Gene synonyms (human)	APA1
Gene (mouse)	Znf410
Gene synonyms (mouse)	Apa1, D12Ertd748e, Zfp410
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	15
Consensus	nYATTATGGGATGbn
GC content	36.93%
Information content (bits; total / per base)	21.286 / 1.419
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9118

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.811	0.828	0.772	0.786	0.721	0.737
Overall, 4 experiments	best	1.0	1.0	1.0	1.0	0.941	0.951
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	1.0	0.923	0.936
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	1.0	0.923	0.936
Non-Methyl HT-SELEX, 3 experiments	median	0.621	0.656	0.545	0.573	0.519	0.539
Non-Methyl HT-SELEX, 3 experiments	best	1.0	1.0	1.0	1.0	0.941	0.951

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	MTF1-like {2.3.3.24} (TFClass)
TFClass ID	TFClass: 2.3.3.24.2
HGNC	HGNC:20144
MGI	MGI:1289280
EntrezGene (human)	GeneID:57862 (SSTAR profile)
EntrezGene (mouse)	GeneID:52708 (SSTAR profile)
UniProt ID (human)	ZN410_HUMAN
UniProt ID (mouse)	ZN410_MOUSE
UniProt AC (human)	Q86VK4 (TFClass)
UniProt AC (mouse)	Q8BKX7 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	ZN410.H12INVIVO.0.SM.D.pcm
PWM	ZN410.H12INVIVO.0.SM.D.pwm
PFM	ZN410.H12INVIVO.0.SM.D.pfm
Alignment	ZN410.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	ZN410.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	ZN410.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	ZN410.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	ZN410.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	ZN410.H12INVIVO.0.SM.D_homer_format_0.001.txt ZN410.H12INVIVO.0.SM.D_homer_format_0.0005.txt ZN410.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2263.25	1833.25	2408.25	2613.25
02	549.5	754.5	468.5	7345.5
03	9094.0	3.0	11.0	10.0
04	3.0	8.0	2.0	9105.0
05	3.0	2.0	0.0	9113.0
06	9109.0	3.0	4.0	2.0
07	0.0	2.0	0.0	9116.0
08	3.0	0.0	9115.0	0.0
09	0.0	1.0	9116.0	1.0
10	6.0	3.0	8627.0	482.0
11	7925.0	815.0	76.0	302.0
12	25.0	20.0	6.0	9067.0
13	1875.0	12.0	7100.0	131.0
14	268.0	2254.0	3250.0	3346.0
15	2199.75	2188.75	2429.75	2299.75

PFM

	A	C	G	T
01	0.248	0.201	0.264	0.287
02	0.06	0.083	0.051	0.806
03	0.997	0.0	0.001	0.001
04	0.0	0.001	0.0	0.999
05	0.0	0.0	0.0	0.999
06	0.999	0.0	0.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	1.0	0.0
09	0.0	0.0	1.0	0.0
10	0.001	0.0	0.946	0.053
11	0.869	0.089	0.008	0.033
12	0.003	0.002	0.001	0.994
13	0.206	0.001	0.779	0.014
14	0.029	0.247	0.356	0.367
15	0.241	0.24	0.266	0.252

PWM

	A	C	G	T
01	-0.007	-0.218	0.055	0.137
02	-1.42	-1.104	-1.578	1.169
03	1.383	-6.069	-5.146	-5.225
04	-6.069	-5.403	-6.279	1.384
05	-6.069	-6.279	-6.909	1.385
06	1.385	-6.069	-5.895	-6.279
07	-6.909	-6.279	-6.909	1.385
08	-6.069	-6.909	1.385	-6.909
09	-6.909	-6.545	1.385	-6.545
10	-5.619	-6.069	1.33	-1.55
11	1.245	-1.027	-3.372	-2.015
12	-4.427	-4.629	-5.619	1.38
13	-0.195	-5.074	1.135	-2.84
14	-2.133	-0.011	0.354	0.383
15	-0.036	-0.041	0.064	0.009

Standard thresholds

P-value	Threshold
0.001	-6.40574
0.0005	-4.13964
0.0001	0.47516