ZN384.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN384.H12INVIVO.0.PSM.A
Gene (human)	ZNF384 (GeneCards)
Gene synonyms (human)	CAGH1, CIZ, NMP4, TNRC1
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	17
Consensus	nvdRRAAAAAAAMGYvn
GC content	26.18%
Information content (bits; total / per base)	18.001 / 1.059
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	325

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (19)	0.944	0.967	0.873	0.928	0.969	0.988	5.994	6.357	394.155	457.237

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.953	0.916	0.932	0.895	0.839	0.823
Overall, 2 experiments	best	0.956	0.922	0.952	0.911	0.917	0.881
Methyl HT-SELEX, 1 experiments	median	0.95	0.909	0.952	0.911	0.917	0.881
Methyl HT-SELEX, 1 experiments	best	0.95	0.909	0.952	0.911	0.917	0.881
Non-Methyl HT-SELEX, 1 experiments	median	0.956	0.922	0.911	0.878	0.761	0.766
Non-Methyl HT-SELEX, 1 experiments	best	0.956	0.922	0.911	0.878	0.761	0.766

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF362-like {2.3.3.37} (TFClass)
TFClass ID	TFClass: 2.3.3.37.2
HGNC	HGNC:11955
MGI
EntrezGene (human)	GeneID:171017 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN384_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8TF68 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN384.H12INVIVO.0.PSM.A.pcm
PWM	ZN384.H12INVIVO.0.PSM.A.pwm
PFM	ZN384.H12INVIVO.0.PSM.A.pfm
Alignment	ZN384.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	ZN384.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	ZN384.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	ZN384.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	ZN384.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	ZN384.H12INVIVO.0.PSM.A_homer_format_0.001.txt ZN384.H12INVIVO.0.PSM.A_homer_format_0.0005.txt ZN384.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	106.0	66.0	89.0	64.0
02	148.0	39.0	108.0	30.0
03	140.0	41.0	94.0	50.0
04	188.0	19.0	92.0	26.0
05	250.0	5.0	51.0	19.0
06	299.0	1.0	22.0	3.0
07	325.0	0.0	0.0	0.0
08	325.0	0.0	0.0	0.0
09	325.0	0.0	0.0	0.0
10	325.0	0.0	0.0	0.0
11	325.0	0.0	0.0	0.0
12	325.0	0.0	0.0	0.0
13	184.0	74.0	67.0	0.0
14	85.0	0.0	240.0	0.0
15	48.0	114.0	8.0	155.0
16	146.25	36.25	122.25	20.25
17	99.0	88.0	70.0	68.0

PFM

	A	C	G	T
01	0.326	0.203	0.274	0.197
02	0.455	0.12	0.332	0.092
03	0.431	0.126	0.289	0.154
04	0.578	0.058	0.283	0.08
05	0.769	0.015	0.157	0.058
06	0.92	0.003	0.068	0.009
07	1.0	0.0	0.0	0.0
08	1.0	0.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	1.0	0.0	0.0	0.0
11	1.0	0.0	0.0	0.0
12	1.0	0.0	0.0	0.0
13	0.566	0.228	0.206	0.0
14	0.262	0.0	0.738	0.0
15	0.148	0.351	0.025	0.477
16	0.45	0.112	0.376	0.062
17	0.305	0.271	0.215	0.209

PWM

	A	C	G	T
01	0.262	-0.204	0.09	-0.234
02	0.592	-0.715	0.28	-0.967
03	0.537	-0.667	0.143	-0.475
04	0.829	-1.397	0.122	-1.103
05	1.112	-2.552	-0.455	-1.397
06	1.29	-3.521	-1.26	-2.923
07	1.373	-4.046	-4.046	-4.046
08	1.373	-4.046	-4.046	-4.046
09	1.373	-4.046	-4.046	-4.046
10	1.373	-4.046	-4.046	-4.046
11	1.373	-4.046	-4.046	-4.046
12	1.373	-4.046	-4.046	-4.046
13	0.808	-0.092	-0.189	-4.046
14	0.044	-4.046	1.071	-4.046
15	-0.514	0.334	-2.17	0.638
16	0.58	-0.786	0.403	-1.338
17	0.194	0.078	-0.146	-0.175

Standard thresholds

P-value	Threshold
0.001	0.80301
0.0005	2.27166
0.0001	5.44061