ZN384.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN384.H12INVITRO.0.PSM.A
Gene (human)	ZNF384 (GeneCards)
Gene synonyms (human)	CAGH1, CIZ, NMP4, TNRC1
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	11
Consensus	nKAAAAAARvn
GC content	22.62%
Information content (bits; total / per base)	12.952 / 1.177
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9701

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (19)	0.901	0.979	0.757	0.961	0.904	0.945	2.899	3.596	300.114	367.959

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.971	0.95	0.961	0.936	0.869	0.867
Overall, 2 experiments	best	0.978	0.964	0.971	0.952	0.956	0.933
Methyl HT-SELEX, 1 experiments	median	0.978	0.964	0.971	0.952	0.956	0.933
Methyl HT-SELEX, 1 experiments	best	0.978	0.964	0.971	0.952	0.956	0.933
Non-Methyl HT-SELEX, 1 experiments	median	0.964	0.936	0.951	0.921	0.783	0.801
Non-Methyl HT-SELEX, 1 experiments	best	0.964	0.936	0.951	0.921	0.783	0.801

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF362-like {2.3.3.37} (TFClass)
TFClass ID	TFClass: 2.3.3.37.2
HGNC	HGNC:11955
MGI
EntrezGene (human)	GeneID:171017 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN384_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8TF68 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN384.H12INVITRO.0.PSM.A.pcm
PWM	ZN384.H12INVITRO.0.PSM.A.pwm
PFM	ZN384.H12INVITRO.0.PSM.A.pfm
Alignment	ZN384.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	ZN384.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	ZN384.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	ZN384.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	ZN384.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	ZN384.H12INVITRO.0.PSM.A_homer_format_0.001.txt ZN384.H12INVITRO.0.PSM.A_homer_format_0.0005.txt ZN384.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2562.5	1846.5	2820.5	2471.5
02	0.0	1812.0	4733.0	3156.0
03	9688.0	0.0	10.0	3.0
04	9676.0	0.0	18.0	7.0
05	9695.0	0.0	6.0	0.0
06	9698.0	0.0	3.0	0.0
07	9691.0	0.0	9.0	1.0
08	9261.0	91.0	346.0	3.0
09	6524.0	1167.0	1634.0	376.0
10	3923.75	1866.75	2683.75	1226.75
11	2935.75	2249.75	2840.75	1674.75

PFM

	A	C	G	T
01	0.264	0.19	0.291	0.255
02	0.0	0.187	0.488	0.325
03	0.999	0.0	0.001	0.0
04	0.997	0.0	0.002	0.001
05	0.999	0.0	0.001	0.0
06	1.0	0.0	0.0	0.0
07	0.999	0.0	0.001	0.0
08	0.955	0.009	0.036	0.0
09	0.673	0.12	0.168	0.039
10	0.404	0.192	0.277	0.126
11	0.303	0.232	0.293	0.173

PWM

	A	C	G	T
01	0.055	-0.272	0.151	0.019
02	-6.964	-0.291	0.668	0.263
03	1.384	-6.964	-5.285	-6.128
04	1.383	-6.964	-4.784	-5.565
05	1.385	-6.964	-5.679	-6.964
06	1.385	-6.964	-6.128	-6.964
07	1.385	-6.964	-5.37	-6.602
08	1.339	-3.259	-1.942	-6.128
09	0.989	-0.73	-0.394	-1.859
10	0.481	-0.261	0.101	-0.681
11	0.191	-0.075	0.158	-0.37

Standard thresholds

P-value	Threshold
0.001	1.67686
0.0005	3.12532
0.0001	7.64889