MotifZN281.H12RSNP.1.SM.D
Gene (human)ZNF281
(GeneCards)
Gene synonyms (human)GZP1, ZBP99
Gene (mouse)Znf281
Gene synonyms (mouse)Zfp281
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length26
ConsensusddddKKdKKdRdKGGAGGGndRKKdd
GC content67.85%
Information content (bits; total / per base)17.719 / 0.682
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words800

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (5) 0.729 0.746 0.541 0.57 0.793 0.817 3.013 3.22 36.42 48.004
Mouse 6 (42) 0.869 0.907 0.707 0.792 0.926 0.947 4.332 4.936 131.054 208.77

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.714 0.645 0.614 0.594 0.54 0.551
best 0.719 0.65 0.621 0.598 0.544 0.555
Methyl HT-SELEX, 1 experiments median 0.708 0.64 0.607 0.589 0.536 0.548
best 0.708 0.64 0.607 0.589 0.536 0.548
Non-Methyl HT-SELEX, 1 experiments median 0.719 0.65 0.621 0.598 0.544 0.555
best 0.719 0.65 0.621 0.598 0.544 0.555
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyZNF148-like {2.3.3.13} (TFClass)
TFClass IDTFClass: 2.3.3.13.2
HGNCHGNC:13075
MGIMGI:3029290
EntrezGene (human)GeneID:23528
(SSTAR profile)
EntrezGene (mouse)GeneID:226442
(SSTAR profile)
UniProt ID (human)ZN281_HUMAN
UniProt ID (mouse)ZN281_MOUSE
UniProt AC (human)Q9Y2X9
(TFClass)
UniProt AC (mouse)Q99LI5
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 6 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01126.75105.75363.75203.75
02108.075.0412.0205.0
03107.089.0405.0199.0
04133.070.0454.0143.0
05108.079.0492.0121.0
0693.069.0491.0147.0
07120.081.0440.0159.0
08112.053.0503.0132.0
09106.048.0497.0149.0
10130.070.0459.0141.0
11140.037.0550.073.0
12190.067.0399.0144.0
1377.021.0587.0115.0
140.012.0779.09.0
1511.07.0782.00.0
16696.01.00.0103.0
170.00.0791.09.0
180.00.0800.00.0
1935.025.0700.040.0
20262.098.0239.0201.0
21202.070.0392.0136.0
22112.042.0537.0109.0
2397.062.0469.0172.0
2467.064.0437.0232.0
25110.589.5360.5239.5
26122.5114.5324.5238.5
PFM
ACGT
010.1580.1320.4550.255
020.1350.0940.5150.256
030.1340.1110.5060.249
040.1660.0880.5680.179
050.1350.0990.6150.151
060.1160.0860.6140.184
070.150.1010.550.199
080.140.0660.6290.165
090.1330.060.6210.186
100.1630.0880.5740.176
110.1750.0460.6880.091
120.2380.0840.4990.18
130.0960.0260.7340.144
140.00.0150.9740.011
150.0140.0090.9780.0
160.870.0010.00.129
170.00.00.9890.011
180.00.01.00.0
190.0440.0310.8750.05
200.3280.1230.2990.251
210.2530.0880.490.17
220.140.0530.6710.136
230.1210.0780.5860.215
240.0840.080.5460.29
250.1380.1120.4510.299
260.1530.1430.4060.298
PWM
ACGT
01-0.451-0.630.5940.018
02-0.609-0.9670.7180.024
03-0.618-0.7990.701-0.005
04-0.404-1.0350.815-0.332
05-0.609-0.9160.895-0.497
06-0.756-1.0490.893-0.305
07-0.505-0.8920.784-0.227
08-0.573-1.3050.917-0.411
09-0.628-1.4010.905-0.292
10-0.426-1.0350.826-0.346
11-0.353-1.6521.006-0.994
12-0.051-1.0770.687-0.325
13-0.941-2.1861.071-0.547
14-4.793-2.6911.354-2.939
15-2.767-3.1471.357-4.793
161.241-4.324-4.793-0.656
17-4.793-4.7931.369-2.939
18-4.793-4.7931.38-4.793
19-1.705-2.0231.247-1.577
200.268-0.7050.1770.005
210.01-1.0350.669-0.382
22-0.573-1.530.982-0.6
23-0.715-1.1530.848-0.149
24-1.077-1.1220.7770.147
25-0.587-0.7940.5850.179
26-0.485-0.5520.4810.175
Standard thresholds
P-value Threshold
0.001 1.94996
0.0005 3.24051
0.0001 5.92321