ZN281.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN281.H12INVIVO.0.P.B
Gene (human)	ZNF281 (GeneCards)
Gene synonyms (human)	GZP1, ZBP99
Gene (mouse)	Znf281
Gene synonyms (mouse)	Zfp281
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	vRKKGGGGGAGGGGhv
GC content	77.71%
Information content (bits; total / per base)	20.32 / 1.27
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.836	0.841	0.743	0.775	0.857	0.877	4.325	4.427	144.409	171.42
Mouse	6 (42)	0.958	0.976	0.896	0.933	0.99	0.994	6.268	6.585	304.833	431.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.692	0.665	0.613	0.601	0.541	0.556
Overall, 2 experiments	best	0.721	0.701	0.624	0.619	0.547	0.566
Methyl HT-SELEX, 1 experiments	median	0.664	0.629	0.602	0.584	0.535	0.546
Methyl HT-SELEX, 1 experiments	best	0.664	0.629	0.602	0.584	0.535	0.546
Non-Methyl HT-SELEX, 1 experiments	median	0.721	0.701	0.624	0.619	0.547	0.566
Non-Methyl HT-SELEX, 1 experiments	best	0.721	0.701	0.624	0.619	0.547	0.566

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF148-like {2.3.3.13} (TFClass)
TFClass ID	TFClass: 2.3.3.13.2
HGNC	HGNC:13075
MGI	MGI:3029290
EntrezGene (human)	GeneID:23528 (SSTAR profile)
EntrezGene (mouse)	GeneID:226442 (SSTAR profile)
UniProt ID (human)	ZN281_HUMAN
UniProt ID (mouse)	ZN281_MOUSE
UniProt AC (human)	Q9Y2X9 (TFClass)
UniProt AC (mouse)	Q99LI5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 6 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN281.H12INVIVO.0.P.B.pcm
PWM	ZN281.H12INVIVO.0.P.B.pwm
PFM	ZN281.H12INVIVO.0.P.B.pfm
Alignment	ZN281.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	ZN281.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	ZN281.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	ZN281.H12INVIVO.0.P.B_meme_format.meme
Transfac format	ZN281.H12INVIVO.0.P.B_transfac_format.txt
Homer format	ZN281.H12INVIVO.0.P.B_homer_format_0.001.txt ZN281.H12INVIVO.0.P.B_homer_format_0.0005.txt ZN281.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	133.0	207.0	569.0	92.0
02	168.0	113.0	607.0	113.0
03	129.0	84.0	606.0	182.0
04	121.0	54.0	224.0	602.0
05	1.0	0.0	999.0	1.0
06	0.0	0.0	1000.0	1.0
07	5.0	0.0	996.0	0.0
08	0.0	2.0	998.0	1.0
09	2.0	1.0	998.0	0.0
10	859.0	32.0	1.0	109.0
11	72.0	0.0	861.0	68.0
12	0.0	0.0	1001.0	0.0
13	4.0	1.0	988.0	8.0
14	9.0	3.0	975.0	14.0
15	353.0	371.0	127.0	150.0
16	304.0	109.0	519.0	69.0

PFM

	A	C	G	T
01	0.133	0.207	0.568	0.092
02	0.168	0.113	0.606	0.113
03	0.129	0.084	0.605	0.182
04	0.121	0.054	0.224	0.601
05	0.001	0.0	0.998	0.001
06	0.0	0.0	0.999	0.001
07	0.005	0.0	0.995	0.0
08	0.0	0.002	0.997	0.001
09	0.002	0.001	0.997	0.0
10	0.858	0.032	0.001	0.109
11	0.072	0.0	0.86	0.068
12	0.0	0.0	1.0	0.0
13	0.004	0.001	0.987	0.008
14	0.009	0.003	0.974	0.014
15	0.353	0.371	0.127	0.15
16	0.304	0.109	0.518	0.069

PWM

	A	C	G	T
01	-0.626	-0.188	0.818	-0.989
02	-0.395	-0.787	0.882	-0.787
03	-0.656	-1.078	0.88	-0.316
04	-0.719	-1.509	-0.11	0.874
05	-4.526	-4.983	1.379	-4.526
06	-4.983	-4.983	1.38	-4.526
07	-3.623	-4.983	1.376	-4.983
08	-4.983	-4.214	1.378	-4.526
09	-4.214	-4.526	1.378	-4.983
10	1.228	-2.011	-4.526	-0.822
11	-1.229	-4.983	1.231	-1.285
12	-4.983	-4.983	1.381	-4.983
13	-3.784	-4.526	1.368	-3.254
14	-3.157	-3.976	1.355	-2.774
15	0.342	0.392	-0.672	-0.507
16	0.193	-0.822	0.726	-1.271

Standard thresholds

P-value	Threshold
0.001	-1.72169
0.0005	-0.00624
0.0001	3.61831