ZN281.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN281.H12INVITRO.0.P.B
Gene (human)	ZNF281 (GeneCards)
Gene synonyms (human)	GZP1, ZBP99
Gene (mouse)	Znf281
Gene synonyms (mouse)	Zfp281
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	SRKKGGGGGAGGGGvv
GC content	78.06%
Information content (bits; total / per base)	20.392 / 1.274
Data sources	ChIP-Seq
Aligned words	1008

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.83	0.839	0.733	0.767	0.857	0.876	4.285	4.386	148.301	174.377
Mouse	6 (42)	0.956	0.976	0.888	0.929	0.989	0.993	6.2	6.514	297.658	420.658

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.707	0.67	0.617	0.605	0.54	0.557
Overall, 2 experiments	best	0.734	0.704	0.628	0.622	0.547	0.567
Methyl HT-SELEX, 1 experiments	median	0.68	0.636	0.606	0.588	0.534	0.547
Methyl HT-SELEX, 1 experiments	best	0.68	0.636	0.606	0.588	0.534	0.547
Non-Methyl HT-SELEX, 1 experiments	median	0.734	0.704	0.628	0.622	0.547	0.567
Non-Methyl HT-SELEX, 1 experiments	best	0.734	0.704	0.628	0.622	0.547	0.567

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF148-like {2.3.3.13} (TFClass)
TFClass ID	TFClass: 2.3.3.13.2
HGNC	HGNC:13075
MGI	MGI:3029290
EntrezGene (human)	GeneID:23528 (SSTAR profile)
EntrezGene (mouse)	GeneID:226442 (SSTAR profile)
UniProt ID (human)	ZN281_HUMAN
UniProt ID (mouse)	ZN281_MOUSE
UniProt AC (human)	Q9Y2X9 (TFClass)
UniProt AC (mouse)	Q99LI5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 6 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN281.H12INVITRO.0.P.B.pcm
PWM	ZN281.H12INVITRO.0.P.B.pwm
PFM	ZN281.H12INVITRO.0.P.B.pfm
Alignment	ZN281.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	ZN281.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	ZN281.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	ZN281.H12INVITRO.0.P.B_meme_format.meme
Transfac format	ZN281.H12INVITRO.0.P.B_transfac_format.txt
Homer format	ZN281.H12INVITRO.0.P.B_homer_format_0.001.txt ZN281.H12INVITRO.0.P.B_homer_format_0.0005.txt ZN281.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	135.0	178.0	604.0	91.0
02	144.0	110.0	667.0	87.0
03	116.0	81.0	656.0	155.0
04	172.0	42.0	203.0	591.0
05	3.0	1.0	1003.0	1.0
06	2.0	1.0	1004.0	1.0
07	4.0	2.0	999.0	3.0
08	2.0	1.0	1005.0	0.0
09	4.0	1.0	1003.0	0.0
10	865.0	32.0	0.0	111.0
11	60.0	0.0	873.0	75.0
12	2.0	2.0	1004.0	0.0
13	5.0	0.0	993.0	10.0
14	6.0	4.0	984.0	14.0
15	363.0	324.0	196.0	125.0
16	307.0	100.0	517.0	84.0

PFM

	A	C	G	T
01	0.134	0.177	0.599	0.09
02	0.143	0.109	0.662	0.086
03	0.115	0.08	0.651	0.154
04	0.171	0.042	0.201	0.586
05	0.003	0.001	0.995	0.001
06	0.002	0.001	0.996	0.001
07	0.004	0.002	0.991	0.003
08	0.002	0.001	0.997	0.0
09	0.004	0.001	0.995	0.0
10	0.858	0.032	0.0	0.11
11	0.06	0.0	0.866	0.074
12	0.002	0.002	0.996	0.0
13	0.005	0.0	0.985	0.01
14	0.006	0.004	0.976	0.014
15	0.36	0.321	0.194	0.124
16	0.305	0.099	0.513	0.083

PWM

	A	C	G	T
01	-0.618	-0.345	0.87	-1.007
02	-0.555	-0.82	0.969	-1.051
03	-0.768	-1.121	0.953	-0.482
04	-0.379	-1.758	-0.215	0.848
05	-3.983	-4.532	1.376	-4.532
06	-4.22	-4.532	1.377	-4.532
07	-3.791	-4.22	1.372	-3.983
08	-4.22	-4.532	1.378	-4.989
09	-3.791	-4.532	1.376	-4.989
10	1.228	-2.018	-4.989	-0.811
11	-1.414	-4.989	1.238	-1.196
12	-4.22	-4.22	1.377	-4.989
13	-3.63	-4.989	1.366	-3.074
14	-3.491	-3.791	1.357	-2.781
15	0.363	0.25	-0.249	-0.694
16	0.196	-0.914	0.715	-1.085

Standard thresholds

P-value	Threshold
0.001	-1.42694
0.0005	0.24056
0.0001	3.75546