ZN276.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN276.H12INVIVO.0.SM.D
Gene (human)	ZNF276 (GeneCards)
Gene synonyms (human)	CENP-Z, ZFP276, ZNF477
Gene (mouse)	Znf276
Gene synonyms (mouse)	Zfp276
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	26
Consensus	bKKAAGGWGGWRKRbdCbvSCTTWRv
GC content	46.73%
Information content (bits; total / per base)	22.601 / 0.869
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	1541

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.657	0.668	0.587	0.592	0.553	0.557
Overall, 2 experiments	best	0.676	0.684	0.606	0.605	0.57	0.568
Methyl HT-SELEX, 1 experiments	median	0.676	0.684	0.606	0.605	0.57	0.568
Methyl HT-SELEX, 1 experiments	best	0.676	0.684	0.606	0.605	0.57	0.568
Non-Methyl HT-SELEX, 1 experiments	median	0.638	0.652	0.568	0.579	0.535	0.546
Non-Methyl HT-SELEX, 1 experiments	best	0.638	0.652	0.568	0.579	0.535	0.546

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZFP91-like {2.3.3.3} (TFClass)
TFClass ID	TFClass: 2.3.3.3.3
HGNC	HGNC:23330
MGI	MGI:1888495
EntrezGene (human)	GeneID:92822 (SSTAR profile)
EntrezGene (mouse)	GeneID:57247 (SSTAR profile)
UniProt ID (human)	ZN276_HUMAN
UniProt ID (mouse)	ZN276_MOUSE
UniProt AC (human)	Q8N554 (TFClass)
UniProt AC (mouse)	Q8CE64 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN276.H12INVIVO.0.SM.D.pcm
PWM	ZN276.H12INVIVO.0.SM.D.pwm
PFM	ZN276.H12INVIVO.0.SM.D.pfm
Alignment	ZN276.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	ZN276.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	ZN276.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	ZN276.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	ZN276.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	ZN276.H12INVIVO.0.SM.D_homer_format_0.001.txt ZN276.H12INVIVO.0.SM.D_homer_format_0.0005.txt ZN276.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	217.25	482.25	538.25	303.25
02	137.75	60.75	279.75	1062.75
03	219.0	19.0	242.0	1061.0
04	1387.0	16.0	95.0	43.0
05	1365.0	4.0	162.0	10.0
06	5.0	3.0	1532.0	1.0
07	52.0	23.0	1458.0	8.0
08	192.0	159.0	140.0	1050.0
09	117.0	91.0	1290.0	43.0
10	6.0	2.0	1524.0	9.0
11	186.0	98.0	104.0	1153.0
12	940.0	37.0	532.0	32.0
13	97.0	86.0	312.0	1046.0
14	895.0	49.0	373.0	224.0
15	46.0	310.0	567.0	618.0
16	798.0	34.0	346.0	363.0
17	82.0	1286.0	134.0	39.0
18	95.0	661.0	481.0	304.0
19	724.0	249.0	392.0	176.0
20	58.0	1194.0	155.0	134.0
21	44.0	1243.0	132.0	122.0
22	36.0	38.0	159.0	1308.0
23	76.0	24.0	149.0	1292.0
24	1220.0	30.0	136.0	155.0
25	1071.75	102.75	228.75	137.75
26	366.25	293.25	665.25	216.25

PFM

	A	C	G	T
01	0.141	0.313	0.349	0.197
02	0.089	0.039	0.182	0.69
03	0.142	0.012	0.157	0.689
04	0.9	0.01	0.062	0.028
05	0.886	0.003	0.105	0.006
06	0.003	0.002	0.994	0.001
07	0.034	0.015	0.946	0.005
08	0.125	0.103	0.091	0.681
09	0.076	0.059	0.837	0.028
10	0.004	0.001	0.989	0.006
11	0.121	0.064	0.067	0.748
12	0.61	0.024	0.345	0.021
13	0.063	0.056	0.202	0.679
14	0.581	0.032	0.242	0.145
15	0.03	0.201	0.368	0.401
16	0.518	0.022	0.225	0.236
17	0.053	0.835	0.087	0.025
18	0.062	0.429	0.312	0.197
19	0.47	0.162	0.254	0.114
20	0.038	0.775	0.101	0.087
21	0.029	0.807	0.086	0.079
22	0.023	0.025	0.103	0.849
23	0.049	0.016	0.097	0.838
24	0.792	0.019	0.088	0.101
25	0.695	0.067	0.148	0.089
26	0.238	0.19	0.432	0.14

PWM

	A	C	G	T
01	-0.569	0.224	0.333	-0.238
02	-1.02	-1.822	-0.318	1.012
03	-0.561	-2.922	-0.462	1.01
04	1.278	-3.077	-1.386	-2.156
05	1.262	-4.195	-0.86	-3.488
06	-4.037	-4.383	1.377	-4.917
07	-1.973	-2.746	1.327	-3.673
08	-0.692	-0.878	-1.004	1.0
09	-1.181	-1.428	1.205	-2.156
10	-3.9	-4.614	1.372	-3.576
11	-0.723	-1.355	-1.297	1.093
12	0.889	-2.299	0.321	-2.437
13	-1.365	-1.483	-0.21	0.996
14	0.84	-2.03	-0.032	-0.539
15	-2.091	-0.216	0.385	0.471
16	0.726	-2.38	-0.107	-0.059
17	-1.53	1.202	-1.047	-2.249
18	-1.386	0.538	0.221	-0.236
19	0.629	-0.434	0.017	-0.778
20	-1.867	1.128	-0.903	-1.047
21	-2.134	1.168	-1.062	-1.14
22	-2.325	-2.274	-0.878	1.219
23	-1.604	-2.707	-0.942	1.207
24	1.149	-2.498	-1.033	-0.903
25	1.02	-1.309	-0.518	-1.02
26	-0.05	-0.271	0.544	-0.574

Standard thresholds

P-value	Threshold
0.001	-0.25434
0.0005	1.16076
0.0001	4.16526