ZN274.H12RSNP.2.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN274.H12RSNP.2.P.D
Gene (human)	ZNF274 (GeneCards)
Gene synonyms (human)	ZKSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	D

Motif length	21
Consensus	MMbvMWKSWGRRARvbChYWY
GC content	47.24%
Information content (bits; total / per base)	12.301 / 0.586
Data sources	ChIP-Seq
Aligned words	926

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	14 (80)	0.594	0.699	0.423	0.494	0.752	0.97	8.689	15.94	1.462	17.051

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.903	0.872	0.797	0.772	0.678	0.68
Overall, 2 experiments	best	0.933	0.907	0.84	0.814	0.715	0.713
Methyl HT-SELEX, 1 experiments	median	0.933	0.907	0.84	0.814	0.715	0.713
Methyl HT-SELEX, 1 experiments	best	0.933	0.907	0.84	0.814	0.715	0.713
Non-Methyl HT-SELEX, 1 experiments	median	0.872	0.836	0.753	0.731	0.642	0.647
Non-Methyl HT-SELEX, 1 experiments	best	0.872	0.836	0.753	0.731	0.642	0.647

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.6
HGNC	HGNC:13068
MGI
EntrezGene (human)	GeneID:10782 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN274_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96GC6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	14 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN274.H12RSNP.2.P.D.pcm
PWM	ZN274.H12RSNP.2.P.D.pwm
PFM	ZN274.H12RSNP.2.P.D.pfm
Alignment	ZN274.H12RSNP.2.P.D.words.tsv
Threshold to P-value map	ZN274.H12RSNP.2.P.D.thr
Motif in other formats
JASPAR format	ZN274.H12RSNP.2.P.D_jaspar_format.txt
MEME format	ZN274.H12RSNP.2.P.D_meme_format.meme
Transfac format	ZN274.H12RSNP.2.P.D_transfac_format.txt
Homer format	ZN274.H12RSNP.2.P.D_homer_format_0.001.txt ZN274.H12RSNP.2.P.D_homer_format_0.0005.txt ZN274.H12RSNP.2.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	143.0	564.0	115.0	104.0
02	688.0	86.0	77.0	75.0
03	151.0	207.0	177.0	391.0
04	493.0	128.0	211.0	94.0
05	193.0	579.0	70.0	84.0
06	282.0	65.0	74.0	505.0
07	99.0	38.0	579.0	210.0
08	83.0	145.0	660.0	38.0
09	520.0	28.0	107.0	271.0
10	74.0	81.0	744.0	27.0
11	645.0	28.0	142.0	111.0
12	127.0	73.0	704.0	22.0
13	758.0	83.0	70.0	15.0
14	721.0	50.0	129.0	26.0
15	444.0	215.0	202.0	65.0
16	83.0	452.0	100.0	291.0
17	55.0	751.0	64.0	56.0
18	274.0	402.0	44.0	206.0
19	43.0	174.0	83.0	626.0
20	559.0	76.0	95.0	196.0
21	59.0	440.0	75.0	352.0

PFM

	A	C	G	T
01	0.154	0.609	0.124	0.112
02	0.743	0.093	0.083	0.081
03	0.163	0.224	0.191	0.422
04	0.532	0.138	0.228	0.102
05	0.208	0.625	0.076	0.091
06	0.305	0.07	0.08	0.545
07	0.107	0.041	0.625	0.227
08	0.09	0.157	0.713	0.041
09	0.562	0.03	0.116	0.293
10	0.08	0.087	0.803	0.029
11	0.697	0.03	0.153	0.12
12	0.137	0.079	0.76	0.024
13	0.819	0.09	0.076	0.016
14	0.779	0.054	0.139	0.028
15	0.479	0.232	0.218	0.07
16	0.09	0.488	0.108	0.314
17	0.059	0.811	0.069	0.06
18	0.296	0.434	0.048	0.222
19	0.046	0.188	0.09	0.676
20	0.604	0.082	0.103	0.212
21	0.064	0.475	0.081	0.38

PWM

	A	C	G	T
01	-0.477	0.886	-0.692	-0.791
02	1.084	-0.978	-1.086	-1.112
03	-0.423	-0.111	-0.266	0.521
04	0.752	-0.587	-0.092	-0.891
05	-0.18	0.912	-1.179	-1.001
06	0.196	-1.252	-1.125	0.776
07	-0.84	-1.77	0.912	-0.097
08	-1.013	-0.463	1.043	-1.77
09	0.805	-2.061	-0.763	0.156
10	-1.125	-1.037	1.162	-2.095
11	1.02	-2.061	-0.484	-0.727
12	-0.594	-1.138	1.107	-2.286
13	1.181	-1.013	-1.179	-2.636
14	1.131	-1.506	-0.579	-2.13
15	0.648	-0.073	-0.135	-1.252
16	-1.013	0.666	-0.83	0.227
17	-1.414	1.172	-1.267	-1.397
18	0.167	0.549	-1.63	-0.116
19	-1.652	-0.283	-1.013	0.99
20	0.877	-1.099	-0.88	-0.165
21	-1.346	0.639	-1.112	0.417

Standard thresholds

P-value	Threshold
0.001	4.22141
0.0005	5.09021
0.0001	6.94216