ZN274.H12INVIVO.2.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN274.H12INVIVO.2.P.B
Gene (human)	ZNF274 (GeneCards)
Gene synonyms (human)	ZKSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	21
Consensus	AGAAYTCATACTGGAGAGAAA
GC content	38.26%
Information content (bits; total / per base)	31.769 / 1.513
Data sources	ChIP-Seq
Aligned words	386

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	14 (80)	0.581	0.728	0.437	0.557	0.769	0.97	8.554	15.823	3.653	14.42

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.795	0.758	0.691	0.67	0.612	0.61
Overall, 2 experiments	best	0.837	0.8	0.727	0.703	0.638	0.634
Methyl HT-SELEX, 1 experiments	median	0.837	0.8	0.727	0.703	0.638	0.634
Methyl HT-SELEX, 1 experiments	best	0.837	0.8	0.727	0.703	0.638	0.634
Non-Methyl HT-SELEX, 1 experiments	median	0.753	0.715	0.654	0.636	0.587	0.586
Non-Methyl HT-SELEX, 1 experiments	best	0.753	0.715	0.654	0.636	0.587	0.586

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.6
HGNC	HGNC:13068
MGI
EntrezGene (human)	GeneID:10782 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN274_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96GC6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	14 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN274.H12INVIVO.2.P.B.pcm
PWM	ZN274.H12INVIVO.2.P.B.pwm
PFM	ZN274.H12INVIVO.2.P.B.pfm
Alignment	ZN274.H12INVIVO.2.P.B.words.tsv
Threshold to P-value map	ZN274.H12INVIVO.2.P.B.thr
Motif in other formats
JASPAR format	ZN274.H12INVIVO.2.P.B_jaspar_format.txt
MEME format	ZN274.H12INVIVO.2.P.B_meme_format.meme
Transfac format	ZN274.H12INVIVO.2.P.B_transfac_format.txt
Homer format	ZN274.H12INVIVO.2.P.B_homer_format_0.001.txt ZN274.H12INVIVO.2.P.B_homer_format_0.0005.txt ZN274.H12INVIVO.2.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	372.0	8.0	4.0	2.0
02	21.0	4.0	336.0	25.0
03	326.0	2.0	56.0	2.0
04	358.0	5.0	21.0	2.0
05	5.0	134.0	13.0	234.0
06	23.0	12.0	2.0	349.0
07	0.0	383.0	0.0	3.0
08	385.0	0.0	1.0	0.0
09	0.0	116.0	4.0	266.0
10	369.0	1.0	12.0	4.0
11	6.0	373.0	4.0	3.0
12	46.0	10.0	8.0	322.0
13	6.0	0.0	380.0	0.0
14	11.0	9.0	363.0	3.0
15	318.0	5.0	26.0	37.0
16	17.0	4.0	365.0	0.0
17	375.0	0.0	2.0	9.0
18	31.0	3.0	347.0	5.0
19	364.0	4.0	18.0	0.0
20	365.0	5.0	16.0	0.0
21	339.0	3.0	42.0	2.0

PFM

	A	C	G	T
01	0.964	0.021	0.01	0.005
02	0.054	0.01	0.87	0.065
03	0.845	0.005	0.145	0.005
04	0.927	0.013	0.054	0.005
05	0.013	0.347	0.034	0.606
06	0.06	0.031	0.005	0.904
07	0.0	0.992	0.0	0.008
08	0.997	0.0	0.003	0.0
09	0.0	0.301	0.01	0.689
10	0.956	0.003	0.031	0.01
11	0.016	0.966	0.01	0.008
12	0.119	0.026	0.021	0.834
13	0.016	0.0	0.984	0.0
14	0.028	0.023	0.94	0.008
15	0.824	0.013	0.067	0.096
16	0.044	0.01	0.946	0.0
17	0.972	0.0	0.005	0.023
18	0.08	0.008	0.899	0.013
19	0.943	0.01	0.047	0.0
20	0.946	0.013	0.041	0.0
21	0.878	0.008	0.109	0.005

PWM

	A	C	G	T
01	1.338	-2.335	-2.882	-3.335
02	-1.472	-2.882	1.237	-1.308
03	1.207	-3.335	-0.533	-3.335
04	1.3	-2.715	-1.472	-3.335
05	-2.715	0.324	-1.911	0.877
06	-1.387	-1.983	-3.335	1.274
07	-4.187	1.367	-4.187	-3.083
08	1.372	-4.187	-3.673	-4.187
09	-4.187	0.181	-2.882	1.004
10	1.33	-3.673	-1.983	-2.882
11	-2.571	1.341	-2.882	-3.083
12	-0.724	-2.143	-2.335	1.194
13	-2.571	-4.187	1.359	-4.187
14	-2.06	-2.235	1.314	-3.083
15	1.182	-2.715	-1.271	-0.934
16	-1.668	-2.882	1.319	-4.187
17	1.346	-4.187	-3.335	-2.235
18	-1.104	-3.083	1.269	-2.715
19	1.316	-2.882	-1.615	-4.187
20	1.319	-2.715	-1.723	-4.187
21	1.246	-3.083	-0.812	-3.335

Standard thresholds

P-value	Threshold
0.001	-6.78839
0.0005	-4.96334
0.0001	-1.04689