ZN274.H12INVITRO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN274.H12INVITRO.1.P.B
Gene (human)	ZNF274 (GeneCards)
Gene synonyms (human)	ZKSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	21
Consensus	GAGAAYTCAYWSWKShRARWR
GC content	44.04%
Information content (bits; total / per base)	20.515 / 0.977
Data sources	ChIP-Seq
Aligned words	222

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	14 (80)	0.648	0.801	0.498	0.66	0.776	0.985	8.924	16.058	7.959	84.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.99	0.986	0.908	0.906	0.728	0.76
Overall, 2 experiments	best	0.995	0.993	0.952	0.947	0.769	0.798
Methyl HT-SELEX, 1 experiments	median	0.995	0.993	0.952	0.947	0.769	0.798
Methyl HT-SELEX, 1 experiments	best	0.995	0.993	0.952	0.947	0.769	0.798
Non-Methyl HT-SELEX, 1 experiments	median	0.985	0.979	0.864	0.866	0.687	0.723
Non-Methyl HT-SELEX, 1 experiments	best	0.985	0.979	0.864	0.866	0.687	0.723

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.6
HGNC	HGNC:13068
MGI
EntrezGene (human)	GeneID:10782 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN274_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96GC6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	14 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN274.H12INVITRO.1.P.B.pcm
PWM	ZN274.H12INVITRO.1.P.B.pwm
PFM	ZN274.H12INVITRO.1.P.B.pfm
Alignment	ZN274.H12INVITRO.1.P.B.words.tsv
Threshold to P-value map	ZN274.H12INVITRO.1.P.B.thr
Motif in other formats
JASPAR format	ZN274.H12INVITRO.1.P.B_jaspar_format.txt
MEME format	ZN274.H12INVITRO.1.P.B_meme_format.meme
Transfac format	ZN274.H12INVITRO.1.P.B_transfac_format.txt
Homer format	ZN274.H12INVITRO.1.P.B_homer_format_0.001.txt ZN274.H12INVITRO.1.P.B_homer_format_0.0005.txt ZN274.H12INVITRO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	23.0	2.0	194.0	3.0
02	213.0	2.0	1.0	6.0
03	2.0	0.0	218.0	2.0
04	164.0	3.0	52.0	3.0
05	208.0	7.0	4.0	3.0
06	7.0	121.0	11.0	83.0
07	14.0	14.0	10.0	184.0
08	4.0	212.0	4.0	2.0
09	201.0	15.0	5.0	1.0
10	16.0	89.0	3.0	114.0
11	171.0	9.0	19.0	23.0
12	10.0	176.0	20.0	16.0
13	55.0	11.0	11.0	145.0
14	15.0	17.0	169.0	21.0
15	26.0	33.0	139.0	24.0
16	111.0	27.0	21.0	63.0
17	30.0	26.0	141.0	25.0
18	178.0	23.0	13.0	8.0
19	58.0	13.0	137.0	14.0
20	167.0	16.0	18.0	21.0
21	152.0	8.0	39.0	23.0

PFM

	A	C	G	T
01	0.104	0.009	0.874	0.014
02	0.959	0.009	0.005	0.027
03	0.009	0.0	0.982	0.009
04	0.739	0.014	0.234	0.014
05	0.937	0.032	0.018	0.014
06	0.032	0.545	0.05	0.374
07	0.063	0.063	0.045	0.829
08	0.018	0.955	0.018	0.009
09	0.905	0.068	0.023	0.005
10	0.072	0.401	0.014	0.514
11	0.77	0.041	0.086	0.104
12	0.045	0.793	0.09	0.072
13	0.248	0.05	0.05	0.653
14	0.068	0.077	0.761	0.095
15	0.117	0.149	0.626	0.108
16	0.5	0.122	0.095	0.284
17	0.135	0.117	0.635	0.113
18	0.802	0.104	0.059	0.036
19	0.261	0.059	0.617	0.063
20	0.752	0.072	0.081	0.095
21	0.685	0.036	0.176	0.104

PWM

	A	C	G	T
01	-0.848	-2.831	1.234	-2.57
02	1.327	-2.831	-3.186	-2.046
03	-2.831	-3.74	1.35	-2.831
04	1.068	-2.57	-0.064	-2.57
05	1.304	-1.918	-2.363	-2.57
06	-1.918	0.766	-1.527	0.395
07	-1.309	-1.309	-1.611	1.182
08	-2.363	1.323	-2.363	-2.831
09	1.27	-1.246	-2.192	-3.186
10	-1.187	0.463	-2.57	0.708
11	1.109	-1.703	-1.027	-0.848
12	-1.611	1.138	-0.979	-1.187
13	-0.009	-1.527	-1.527	0.946
14	-1.246	-1.131	1.097	-0.934
15	-0.732	-0.504	0.904	-0.808
16	0.681	-0.696	-0.934	0.124
17	-0.595	-0.732	0.918	-0.769
18	1.149	-0.848	-1.377	-1.805
19	0.043	-1.377	0.889	-1.309
20	1.086	-1.187	-1.078	-0.934
21	0.992	-1.805	-0.343	-0.848

Standard thresholds

P-value	Threshold
0.001	1.50981
0.0005	2.74106
0.0001	5.36846