ZN274.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN274.H12INVITRO.0.SM.B
Gene (human)	ZNF274 (GeneCards)
Gene synonyms (human)	ZKSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	vhGAGAACTCAYRb
GC content	46.4%
Information content (bits; total / per base)	17.026 / 1.216
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9984

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	14 (80)	0.701	0.871	0.572	0.804	0.764	0.985	4.27	6.313	12.643	94.638

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	1.0	0.999	0.99	0.989	0.81	0.845
Overall, 2 experiments	best	1.0	1.0	0.999	0.998	0.849	0.876
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.999	0.998	0.849	0.876
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.999	0.998	0.849	0.876
Non-Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.981	0.98	0.77	0.813
Non-Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.981	0.98	0.77	0.813

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.6
HGNC	HGNC:13068
MGI
EntrezGene (human)	GeneID:10782 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN274_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96GC6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	14 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN274.H12INVITRO.0.SM.B.pcm
PWM	ZN274.H12INVITRO.0.SM.B.pwm
PFM	ZN274.H12INVITRO.0.SM.B.pfm
Alignment	ZN274.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	ZN274.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	ZN274.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	ZN274.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	ZN274.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	ZN274.H12INVITRO.0.SM.B_homer_format_0.001.txt ZN274.H12INVITRO.0.SM.B_homer_format_0.0005.txt ZN274.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2967.75	1706.75	3677.75	1631.75
02	1785.0	4847.0	480.0	2872.0
03	761.0	17.0	9178.0	28.0
04	9899.0	34.0	24.0	27.0
05	13.0	7.0	9949.0	15.0
06	8000.0	2.0	1964.0	18.0
07	9965.0	4.0	4.0	11.0
08	14.0	9635.0	246.0	89.0
09	122.0	102.0	57.0	9703.0
10	33.0	9892.0	25.0	34.0
11	8302.0	1339.0	208.0	135.0
12	1074.0	3117.0	78.0	5715.0
13	6556.75	905.75	1956.75	564.75
14	1539.25	3826.25	1580.25	3038.25

PFM

	A	C	G	T
01	0.297	0.171	0.368	0.163
02	0.179	0.485	0.048	0.288
03	0.076	0.002	0.919	0.003
04	0.991	0.003	0.002	0.003
05	0.001	0.001	0.996	0.002
06	0.801	0.0	0.197	0.002
07	0.998	0.0	0.0	0.001
08	0.001	0.965	0.025	0.009
09	0.012	0.01	0.006	0.972
10	0.003	0.991	0.003	0.003
11	0.832	0.134	0.021	0.014
12	0.108	0.312	0.008	0.572
13	0.657	0.091	0.196	0.057
14	0.154	0.383	0.158	0.304

PWM

	A	C	G	T
01	0.173	-0.38	0.387	-0.425
02	-0.335	0.663	-1.645	0.14
03	-1.186	-4.863	1.301	-4.412
04	1.377	-4.231	-4.554	-4.446
05	-5.095	-5.593	1.382	-4.973
06	1.164	-6.364	-0.239	-4.813
07	1.384	-5.982	-5.982	-5.235
08	-5.032	1.35	-2.309	-3.309
09	-3.001	-3.176	-3.741	1.357
10	-4.259	1.376	-4.516	-4.231
11	1.201	-0.622	-2.475	-2.901
12	-0.842	0.222	-3.438	0.828
13	0.965	-1.012	-0.243	-1.483
14	-0.483	0.427	-0.457	0.196

Standard thresholds

P-value	Threshold
0.001	0.30326
0.0005	1.89326
0.0001	5.26151