ZN274.H12CORE.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN274.H12CORE.1.P.B
Gene (human)	ZNF274 (GeneCards)
Gene synonyms (human)	ZKSCAN19
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	21
Consensus	GAGAAYTCAYdSWKShRARWR
GC content	43.78%
Information content (bits; total / per base)	20.581 / 0.98
Data sources	ChIP-Seq
Aligned words	222

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	14 (80)	0.65	0.802	0.497	0.662	0.786	0.984	8.949	16.056	8.377	83.092

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.99	0.986	0.907	0.906	0.725	0.759
Overall, 2 experiments	best	0.995	0.993	0.952	0.947	0.766	0.796
Methyl HT-SELEX, 1 experiments	median	0.995	0.993	0.952	0.947	0.766	0.796
Methyl HT-SELEX, 1 experiments	best	0.995	0.993	0.952	0.947	0.766	0.796
Non-Methyl HT-SELEX, 1 experiments	median	0.985	0.979	0.863	0.865	0.684	0.722
Non-Methyl HT-SELEX, 1 experiments	best	0.985	0.979	0.863	0.865	0.684	0.722

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.6
HGNC	HGNC:13068
MGI
EntrezGene (human)	GeneID:10782 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN274_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96GC6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	14 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN274.H12CORE.1.P.B.pcm
PWM	ZN274.H12CORE.1.P.B.pwm
PFM	ZN274.H12CORE.1.P.B.pfm
Alignment	ZN274.H12CORE.1.P.B.words.tsv
Threshold to P-value map	ZN274.H12CORE.1.P.B.thr
Motif in other formats
JASPAR format	ZN274.H12CORE.1.P.B_jaspar_format.txt
MEME format	ZN274.H12CORE.1.P.B_meme_format.meme
Transfac format	ZN274.H12CORE.1.P.B_transfac_format.txt
Homer format	ZN274.H12CORE.1.P.B_homer_format_0.001.txt ZN274.H12CORE.1.P.B_homer_format_0.0005.txt ZN274.H12CORE.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	27.0	2.0	191.0	2.0
02	214.0	0.0	1.0	7.0
03	2.0	0.0	218.0	2.0
04	165.0	2.0	52.0	3.0
05	209.0	5.0	5.0	3.0
06	13.0	122.0	9.0	78.0
07	15.0	13.0	9.0	185.0
08	5.0	211.0	4.0	2.0
09	201.0	16.0	5.0	0.0
10	19.0	87.0	3.0	113.0
11	172.0	8.0	21.0	21.0
12	11.0	176.0	19.0	16.0
13	54.0	10.0	13.0	145.0
14	17.0	18.0	168.0	19.0
15	27.0	32.0	140.0	23.0
16	110.0	26.0	22.0	64.0
17	31.0	25.0	142.0	24.0
18	179.0	23.0	11.0	9.0
19	56.0	13.0	139.0	14.0
20	168.0	16.0	18.0	20.0
21	154.0	9.0	37.0	22.0

PFM

	A	C	G	T
01	0.122	0.009	0.86	0.009
02	0.964	0.0	0.005	0.032
03	0.009	0.0	0.982	0.009
04	0.743	0.009	0.234	0.014
05	0.941	0.023	0.023	0.014
06	0.059	0.55	0.041	0.351
07	0.068	0.059	0.041	0.833
08	0.023	0.95	0.018	0.009
09	0.905	0.072	0.023	0.0
10	0.086	0.392	0.014	0.509
11	0.775	0.036	0.095	0.095
12	0.05	0.793	0.086	0.072
13	0.243	0.045	0.059	0.653
14	0.077	0.081	0.757	0.086
15	0.122	0.144	0.631	0.104
16	0.495	0.117	0.099	0.288
17	0.14	0.113	0.64	0.108
18	0.806	0.104	0.05	0.041
19	0.252	0.059	0.626	0.063
20	0.757	0.072	0.081	0.09
21	0.694	0.041	0.167	0.099

PWM

	A	C	G	T
01	-0.696	-2.831	1.219	-2.831
02	1.332	-3.74	-3.186	-1.918
03	-2.831	-3.74	1.35	-2.831
04	1.074	-2.831	-0.064	-2.57
05	1.308	-2.192	-2.192	-2.57
06	-1.377	0.775	-1.703	0.333
07	-1.246	-1.377	-1.703	1.187
08	-2.192	1.318	-2.363	-2.831
09	1.27	-1.187	-2.192	-3.74
10	-1.027	0.441	-2.57	0.699
11	1.115	-1.805	-0.934	-0.934
12	-1.527	1.138	-1.027	-1.187
13	-0.027	-1.611	-1.377	0.946
14	-1.131	-1.078	1.092	-1.027
15	-0.696	-0.533	0.911	-0.848
16	0.672	-0.732	-0.89	0.139
17	-0.564	-0.769	0.925	-0.808
18	1.154	-0.848	-1.527	-1.703
19	0.009	-1.377	0.904	-1.309
20	1.092	-1.187	-1.078	-0.979
21	1.005	-1.703	-0.394	-0.89

Standard thresholds

P-value	Threshold
0.001	1.45946
0.0005	2.70041
0.0001	5.34526