ZN250.H12INVITRO.1.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN250.H12INVITRO.1.M.C
Gene (human)	ZNF250 (GeneCards)
Gene synonyms (human)	ZNF647
Gene (mouse)	Znf250
Gene synonyms (mouse)	Zfp647, Znf647
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	11
Consensus	nhRRGCCTAhn
GC content	53.21%
Information content (bits; total / per base)	10.555 / 0.96
Data sources	Methyl-HT-SELEX
Aligned words	9845

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.468	0.472	0.314	0.316	0.41	0.418	0.753	0.8	6.824	9.046

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.945	0.931	0.806	0.801	0.665	0.687
Methyl HT-SELEX, 1 experiments	best	0.945	0.931	0.806	0.801	0.665	0.687

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.160
HGNC	HGNC:13044
MGI	MGI:3052806
EntrezGene (human)	GeneID:58500 (SSTAR profile)
EntrezGene (mouse)	GeneID:239546 (SSTAR profile)
UniProt ID (human)	ZN250_HUMAN
UniProt ID (mouse)	ZN250_MOUSE
UniProt AC (human)	P15622 (TFClass)
UniProt AC (mouse)	Q7TNU6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	1

PCM	ZN250.H12INVITRO.1.M.C.pcm
PWM	ZN250.H12INVITRO.1.M.C.pwm
PFM	ZN250.H12INVITRO.1.M.C.pfm
Alignment	ZN250.H12INVITRO.1.M.C.words.tsv
Threshold to P-value map	ZN250.H12INVITRO.1.M.C.thr
Motif in other formats
JASPAR format	ZN250.H12INVITRO.1.M.C_jaspar_format.txt
MEME format	ZN250.H12INVITRO.1.M.C_meme_format.meme
Transfac format	ZN250.H12INVITRO.1.M.C_transfac_format.txt
Homer format	ZN250.H12INVITRO.1.M.C_homer_format_0.001.txt ZN250.H12INVITRO.1.M.C_homer_format_0.0005.txt ZN250.H12INVITRO.1.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2443.25	2437.25	1954.25	3010.25
02	1961.25	2290.25	1371.25	4222.25
03	6065.0	965.0	2050.0	765.0
04	1905.0	412.0	6636.0	892.0
05	102.0	38.0	9666.0	39.0
06	1.0	9844.0	0.0	0.0
07	6.0	9801.0	38.0	0.0
08	4.0	270.0	1.0	9570.0
09	9051.0	435.0	126.0	233.0
10	1757.5	3261.5	946.5	3879.5
11	1981.25	2580.25	2501.25	2782.25

PFM

	A	C	G	T
01	0.248	0.248	0.199	0.306
02	0.199	0.233	0.139	0.429
03	0.616	0.098	0.208	0.078
04	0.193	0.042	0.674	0.091
05	0.01	0.004	0.982	0.004
06	0.0	1.0	0.0	0.0
07	0.001	0.996	0.004	0.0
08	0.0	0.027	0.0	0.972
09	0.919	0.044	0.013	0.024
10	0.179	0.331	0.096	0.394
11	0.201	0.262	0.254	0.283

PWM

	A	C	G	T
01	-0.007	-0.01	-0.23	0.201
02	-0.227	-0.072	-0.584	0.539
03	0.901	-0.935	-0.183	-1.166
04	-0.256	-1.783	0.991	-1.013
05	-3.162	-4.113	1.367	-4.089
06	-6.616	1.385	-6.977	-6.977
07	-5.693	1.381	-4.113	-6.977
08	-5.969	-2.202	-6.616	1.357
09	1.302	-1.729	-2.955	-2.349
10	-0.336	0.281	-0.954	0.455
11	-0.217	0.047	0.016	0.122

Standard thresholds

P-value	Threshold
0.001	4.540715
0.0005	5.729365
0.0001	7.65584