ZN177.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN177.H12INVIVO.0.SM.D
Gene (human)	ZNF177 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	24
Consensus	nhWSRbbdbbvvbYKMGATCdAvn
GC content	48.56%
Information content (bits; total / per base)	13.235 / 0.551
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9848

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.822	0.835	0.641	0.675	0.559	0.596
Overall, 2 experiments	best	0.889	0.893	0.683	0.714	0.58	0.62
Methyl HT-SELEX, 1 experiments	median	0.754	0.776	0.599	0.636	0.537	0.572
Methyl HT-SELEX, 1 experiments	best	0.754	0.776	0.599	0.636	0.537	0.572
Non-Methyl HT-SELEX, 1 experiments	median	0.889	0.893	0.683	0.714	0.58	0.62
Non-Methyl HT-SELEX, 1 experiments	best	0.889	0.893	0.683	0.714	0.58	0.62

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF177-like {2.3.3.40} (TFClass)
TFClass ID	TFClass: 2.3.3.40.1
HGNC	HGNC:12966
MGI
EntrezGene (human)	GeneID:100529215 (SSTAR profile) GeneID:7730 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN177_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q13360 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN177.H12INVIVO.0.SM.D.pcm
PWM	ZN177.H12INVIVO.0.SM.D.pwm
PFM	ZN177.H12INVIVO.0.SM.D.pfm
Alignment	ZN177.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	ZN177.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	ZN177.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	ZN177.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	ZN177.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	ZN177.H12INVIVO.0.SM.D_homer_format_0.001.txt ZN177.H12INVIVO.0.SM.D_homer_format_0.0005.txt ZN177.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3372.5	2791.5	1565.5	2118.5
02	5509.0	1438.0	1377.0	1524.0
03	1026.0	947.0	762.0	7113.0
04	905.0	1704.0	6370.0	869.0
05	6264.0	1094.0	1513.0	977.0
06	1031.0	5003.0	2092.0	1722.0
07	721.0	3661.0	739.0	4727.0
08	1844.0	1187.0	2957.0	3860.0
09	1467.0	1813.0	2476.0	4092.0
10	1490.0	1822.0	3447.0	3089.0
11	2402.0	5027.0	1370.0	1049.0
12	2550.0	4522.0	1562.0	1214.0
13	1228.0	3249.0	3242.0	2129.0
14	844.0	3469.0	415.0	5120.0
15	670.0	446.0	1558.0	7174.0
16	3077.0	6234.0	106.0	431.0
17	93.0	160.0	9540.0	55.0
18	9442.0	154.0	226.0	26.0
19	88.0	2156.0	72.0	7532.0
20	225.0	9219.0	90.0	314.0
21	2408.0	802.0	4450.0	2188.0
22	8230.0	627.0	470.0	521.0
23	2805.0	1935.0	3909.0	1199.0
24	2426.25	2607.25	2386.25	2428.25

PFM

	A	C	G	T
01	0.342	0.283	0.159	0.215
02	0.559	0.146	0.14	0.155
03	0.104	0.096	0.077	0.722
04	0.092	0.173	0.647	0.088
05	0.636	0.111	0.154	0.099
06	0.105	0.508	0.212	0.175
07	0.073	0.372	0.075	0.48
08	0.187	0.121	0.3	0.392
09	0.149	0.184	0.251	0.416
10	0.151	0.185	0.35	0.314
11	0.244	0.51	0.139	0.107
12	0.259	0.459	0.159	0.123
13	0.125	0.33	0.329	0.216
14	0.086	0.352	0.042	0.52
15	0.068	0.045	0.158	0.728
16	0.312	0.633	0.011	0.044
17	0.009	0.016	0.969	0.006
18	0.959	0.016	0.023	0.003
19	0.009	0.219	0.007	0.765
20	0.023	0.936	0.009	0.032
21	0.245	0.081	0.452	0.222
22	0.836	0.064	0.048	0.053
23	0.285	0.196	0.397	0.122
24	0.246	0.265	0.242	0.247

PWM

	A	C	G	T
01	0.314	0.125	-0.452	-0.15
02	0.805	-0.537	-0.58	-0.479
03	-0.874	-0.954	-1.171	1.06
04	-0.999	-0.368	0.95	-1.04
05	0.933	-0.81	-0.486	-0.923
06	-0.869	0.709	-0.163	-0.357
07	-1.226	0.396	-1.201	0.652
08	-0.289	-0.729	0.183	0.449
09	-0.517	-0.306	0.006	0.508
10	-0.502	-0.301	0.336	0.227
11	-0.025	0.713	-0.585	-0.852
12	0.035	0.608	-0.454	-0.706
13	-0.695	0.277	0.275	-0.145
14	-1.069	0.343	-1.776	0.732
15	-1.299	-1.704	-0.457	1.069
16	0.223	0.928	-3.125	-1.738
17	-3.253	-2.72	1.354	-3.761
18	1.344	-2.758	-2.379	-4.467
19	-3.307	-0.133	-3.502	1.118
20	-2.383	1.32	-3.285	-2.053
21	-0.022	-1.12	0.592	-0.118
22	1.206	-1.365	-1.652	-1.55
23	0.13	-0.241	0.462	-0.719
24	-0.015	0.057	-0.031	-0.014

Standard thresholds

P-value	Threshold
0.001	3.81876
0.0005	4.82636
0.0001	6.92306