ZN140.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZN140.H12INVITRO.0.P.B
Gene (human)	ZNF140 (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	23
Consensus	hhbhWRCAATTCYRCTCMhhvvb
GC content	51.15%
Information content (bits; total / per base)	18.765 / 0.816
Data sources	ChIP-Seq
Aligned words	1013

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.823	0.906	0.766	0.887	0.852	0.926	6.846	10.49	179.174	393.553

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.642	0.671	0.55	0.58	0.519	0.542
Overall, 2 experiments	best	0.667	0.702	0.555	0.593	0.521	0.548
Methyl HT-SELEX, 1 experiments	median	0.667	0.702	0.555	0.593	0.517	0.548
Methyl HT-SELEX, 1 experiments	best	0.667	0.702	0.555	0.593	0.517	0.548
Non-Methyl HT-SELEX, 1 experiments	median	0.617	0.639	0.545	0.566	0.521	0.536
Non-Methyl HT-SELEX, 1 experiments	best	0.617	0.639	0.545	0.566	0.521	0.536

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZNF302-like {2.3.3.44} (TFClass)
TFClass ID	TFClass: 2.3.3.44.4
HGNC	HGNC:12925
MGI
EntrezGene (human)	GeneID:7699 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZN140_HUMAN
UniProt ID (mouse)
UniProt AC (human)	P52738 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZN140.H12INVITRO.0.P.B.pcm
PWM	ZN140.H12INVITRO.0.P.B.pwm
PFM	ZN140.H12INVITRO.0.P.B.pfm
Alignment	ZN140.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	ZN140.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	ZN140.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	ZN140.H12INVITRO.0.P.B_meme_format.meme
Transfac format	ZN140.H12INVITRO.0.P.B_transfac_format.txt
Homer format	ZN140.H12INVITRO.0.P.B_homer_format_0.001.txt ZN140.H12INVITRO.0.P.B_homer_format_0.0005.txt ZN140.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	522.0	182.0	151.0	158.0
02	118.0	529.0	107.0	259.0
03	107.0	589.0	123.0	194.0
04	123.0	604.0	97.0	189.0
05	658.0	68.0	74.0	213.0
06	117.0	43.0	777.0	76.0
07	14.0	952.0	14.0	33.0
08	827.0	85.0	35.0	66.0
09	877.0	55.0	59.0	22.0
10	9.0	60.0	11.0	933.0
11	8.0	17.0	9.0	979.0
12	37.0	942.0	25.0	9.0
13	84.0	698.0	3.0	228.0
14	451.0	34.0	517.0	11.0
15	20.0	875.0	55.0	63.0
16	11.0	118.0	12.0	872.0
17	8.0	943.0	5.0	57.0
18	171.0	688.0	28.0	126.0
19	178.0	199.0	85.0	551.0
20	458.0	171.0	170.0	214.0
21	161.0	214.0	491.0	147.0
22	209.0	222.0	410.0	172.0
23	131.0	229.0	142.0	511.0

PFM

	A	C	G	T
01	0.515	0.18	0.149	0.156
02	0.116	0.522	0.106	0.256
03	0.106	0.581	0.121	0.192
04	0.121	0.596	0.096	0.187
05	0.65	0.067	0.073	0.21
06	0.115	0.042	0.767	0.075
07	0.014	0.94	0.014	0.033
08	0.816	0.084	0.035	0.065
09	0.866	0.054	0.058	0.022
10	0.009	0.059	0.011	0.921
11	0.008	0.017	0.009	0.966
12	0.037	0.93	0.025	0.009
13	0.083	0.689	0.003	0.225
14	0.445	0.034	0.51	0.011
15	0.02	0.864	0.054	0.062
16	0.011	0.116	0.012	0.861
17	0.008	0.931	0.005	0.056
18	0.169	0.679	0.028	0.124
19	0.176	0.196	0.084	0.544
20	0.452	0.169	0.168	0.211
21	0.159	0.211	0.485	0.145
22	0.206	0.219	0.405	0.17
23	0.129	0.226	0.14	0.504

PWM

	A	C	G	T
01	0.72	-0.328	-0.513	-0.468
02	-0.756	0.733	-0.852	0.022
03	-0.852	0.84	-0.715	-0.264
04	-0.715	0.865	-0.949	-0.29
05	0.951	-1.297	-1.214	-0.172
06	-0.764	-1.741	1.116	-1.188
07	-2.786	1.319	-2.786	-1.994
08	1.179	-1.078	-1.938	-1.326
09	1.237	-1.503	-1.435	-2.374
10	-3.168	-1.418	-2.997	1.299
11	-3.266	-2.611	-3.168	1.347
12	-1.885	1.309	-2.255	-3.168
13	-1.09	1.01	-3.987	-0.104
14	0.574	-1.965	0.71	-2.997
15	-2.462	1.235	-1.503	-1.371
16	-2.997	-0.756	-2.922	1.232
17	-3.266	1.31	-3.635	-1.468
18	-0.389	0.995	-2.149	-0.691
19	-0.35	-0.239	-1.078	0.774
20	0.589	-0.389	-0.395	-0.167
21	-0.449	-0.167	0.659	-0.539
22	-0.191	-0.131	0.479	-0.384
23	-0.653	-0.1	-0.573	0.699

Standard thresholds

P-value	Threshold
0.001	1.75501
0.0005	2.98406
0.0001	5.59576