MotifZIC5.H12INVIVO.2.S.C
Gene (human)ZIC5
(GeneCards)
Gene synonyms (human)
Gene (mouse)Zic5
Gene synonyms (mouse)Opr
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length17
ConsensusndMdCAGCGGGGGGTMn
GC content73.4%
Information content (bits; total / per base)20.217 / 1.189
Data sourcesHT-SELEX
Aligned words4465

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 9 (61) 0.856 0.946 0.79 0.92 0.794 0.913 2.815 4.047 295.167 476.143

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.961 0.963 0.787 0.812 0.632 0.681
best 0.999 0.999 0.875 0.891 0.675 0.729
Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.875 0.891 0.675 0.729
best 0.999 0.999 0.875 0.891 0.675 0.729
Non-Methyl HT-SELEX, 1 experiments median 0.922 0.928 0.699 0.734 0.589 0.632
best 0.922 0.928 0.699 0.734 0.589 0.632
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.11
HGNCHGNC:20322
MGIMGI:1929518
EntrezGene (human)GeneID:85416
(SSTAR profile)
EntrezGene (mouse)GeneID:65100
(SSTAR profile)
UniProt ID (human)ZIC5_HUMAN
UniProt ID (mouse)ZIC5_MOUSE
UniProt AC (human)Q96T25
(TFClass)
UniProt AC (mouse)Q7TQ40
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 9 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01930.75980.751304.751248.75
02926.0178.01792.01569.0
03630.03314.0468.053.0
041527.0214.01826.0898.0
0532.04266.085.082.0
063743.0195.0303.0224.0
07484.02.03978.01.0
0814.04262.074.0115.0
09302.01.04161.01.0
105.09.04436.015.0
1127.00.04435.03.0
1289.04.04287.085.0
138.07.04441.09.0
149.00.04408.048.0
1551.0259.0315.03840.0
161116.02607.0638.0104.0
17858.01082.01383.01142.0
PFM
ACGT
010.2080.220.2920.28
020.2070.040.4010.351
030.1410.7420.1050.012
040.3420.0480.4090.201
050.0070.9550.0190.018
060.8380.0440.0680.05
070.1080.00.8910.0
080.0030.9550.0170.026
090.0680.00.9320.0
100.0010.0020.9940.003
110.0060.00.9930.001
120.020.0010.960.019
130.0020.0020.9950.002
140.0020.00.9870.011
150.0110.0580.0710.86
160.250.5840.1430.023
170.1920.2420.310.256
PWM
ACGT
01-0.181-0.1290.1560.112
02-0.186-1.8260.4730.34
03-0.5711.087-0.867-3.01
040.313-1.6440.491-0.217
05-3.491.339-2.553-2.588
061.209-1.736-1.299-1.599
07-0.833-5.6081.269-5.888
08-4.2411.338-2.688-2.257
09-1.302-5.8881.314-5.888
10-5.059-4.6131.378-4.18
11-3.649-6.2771.378-5.39
12-2.508-5.2111.344-2.553
13-4.707-4.8111.379-4.613
14-4.613-6.2771.372-3.106
15-3.047-1.455-1.261.234
16-0.00.847-0.558-2.355
17-0.263-0.0310.2140.023
Standard thresholds
P-value Threshold
0.001 -1.40144
0.0005 0.28281
0.0001 3.81601