MotifZIC5.H12INVITRO.1.M.C
Gene (human)ZIC5
(GeneCards)
Gene synonyms (human)
Gene (mouse)Zic5
Gene synonyms (mouse)Opr
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length17
ConsensusndCACAGCAGGGGGTMn
GC content67.83%
Information content (bits; total / per base)22.461 / 1.321
Data sourcesMethyl-HT-SELEX
Aligned words9323

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 9 (61) 0.925 0.971 0.883 0.955 0.876 0.945 3.585 5.304 334.013 491.155

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.963 0.965 0.779 0.81 0.624 0.677
best 1.0 1.0 0.87 0.89 0.668 0.726
Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.87 0.89 0.668 0.726
best 1.0 1.0 0.87 0.89 0.668 0.726
Non-Methyl HT-SELEX, 1 experiments median 0.926 0.93 0.689 0.73 0.581 0.628
best 0.926 0.93 0.689 0.73 0.581 0.628
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.11
HGNCHGNC:20322
MGIMGI:1929518
EntrezGene (human)GeneID:85416
(SSTAR profile)
EntrezGene (mouse)GeneID:65100
(SSTAR profile)
UniProt ID (human)ZIC5_HUMAN
UniProt ID (mouse)ZIC5_MOUSE
UniProt AC (human)Q96T25
(TFClass)
UniProt AC (mouse)Q7TQ40
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 9 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011899.252946.251850.252627.25
021684.75409.753305.753922.75
031027.08201.088.07.0
047744.0205.0193.01181.0
054.09305.01.013.0
068837.0407.049.030.0
0774.06.09243.00.0
084.09070.07.0242.0
096357.00.02966.00.0
101.00.09291.031.0
111.01.09321.00.0
1272.03.09100.0148.0
1322.02.09274.025.0
1427.03.08811.0482.0
1513.01259.0703.07348.0
161973.255995.251054.25300.25
171794.02496.01932.03101.0
PFM
ACGT
010.2040.3160.1980.282
020.1810.0440.3550.421
030.110.880.0090.001
040.8310.0220.0210.127
050.00.9980.00.001
060.9480.0440.0050.003
070.0080.0010.9910.0
080.00.9730.0010.026
090.6820.00.3180.0
100.00.00.9970.003
110.00.01.00.0
120.0080.00.9760.016
130.0020.00.9950.003
140.0030.00.9450.052
150.0010.1350.0750.788
160.2120.6430.1130.032
170.1920.2680.2070.333
PWM
ACGT
01-0.2050.234-0.2310.12
02-0.324-1.7340.3490.52
03-0.8181.257-3.252-5.527
041.2-2.421-2.48-0.679
05-5.9171.384-6.566-5.028
061.332-1.741-3.818-4.28
07-3.42-5.641.377-6.929
08-5.9171.358-5.527-2.257
091.003-6.9290.241-6.929
10-6.566-6.9291.382-4.25
11-6.566-6.5661.385-6.929
12-3.447-6.091.361-2.742
13-4.565-6.31.38-4.449
14-4.378-6.091.329-1.572
15-5.028-0.615-1.1961.148
16-0.1660.944-0.792-2.043
17-0.2610.068-0.1870.285
Standard thresholds
P-value Threshold
0.001 -5.47799
0.0005 -3.38419
0.0001 1.02206