ZIC5.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZIC5.H12INVITRO.0.P.B
Gene (human)	ZIC5 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Zic5
Gene synonyms (mouse)	Opr
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	dCnCMGCRGGRGGYS
GC content	76.06%
Information content (bits; total / per base)	16.464 / 1.098
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (61)	0.945	0.98	0.906	0.965	0.91	0.965	3.876	5.29	413.187	535.377

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.96	0.963	0.771	0.804	0.613	0.67
Overall, 2 experiments	best	1.0	1.0	0.863	0.885	0.657	0.72
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.863	0.885	0.657	0.72
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.863	0.885	0.657	0.72
Non-Methyl HT-SELEX, 1 experiments	median	0.921	0.926	0.678	0.724	0.569	0.621
Non-Methyl HT-SELEX, 1 experiments	best	0.921	0.926	0.678	0.724	0.569	0.621

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.11
HGNC	HGNC:20322
MGI	MGI:1929518
EntrezGene (human)	GeneID:85416 (SSTAR profile)
EntrezGene (mouse)	GeneID:65100 (SSTAR profile)
UniProt ID (human)	ZIC5_HUMAN
UniProt ID (mouse)	ZIC5_MOUSE
UniProt AC (human)	Q96T25 (TFClass)
UniProt AC (mouse)	Q7TQ40 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZIC5.H12INVITRO.0.P.B.pcm
PWM	ZIC5.H12INVITRO.0.P.B.pwm
PFM	ZIC5.H12INVITRO.0.P.B.pfm
Alignment	ZIC5.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	ZIC5.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	ZIC5.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	ZIC5.H12INVITRO.0.P.B_meme_format.meme
Transfac format	ZIC5.H12INVITRO.0.P.B_transfac_format.txt
Homer format	ZIC5.H12INVITRO.0.P.B_homer_format_0.001.txt ZIC5.H12INVITRO.0.P.B_homer_format_0.0005.txt ZIC5.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	204.0	105.0	459.0	232.0
02	88.0	844.0	68.0	0.0
03	381.0	202.0	231.0	186.0
04	1.0	988.0	2.0	9.0
05	701.0	174.0	81.0	44.0
06	45.0	47.0	906.0	2.0
07	2.0	944.0	0.0	54.0
08	601.0	1.0	392.0	6.0
09	2.0	2.0	981.0	15.0
10	0.0	2.0	997.0	1.0
11	182.0	26.0	702.0	90.0
12	60.0	22.0	881.0	37.0
13	30.0	24.0	888.0	58.0
14	4.0	460.0	132.0	404.0
15	112.0	635.0	213.0	40.0

PFM

	A	C	G	T
01	0.204	0.105	0.459	0.232
02	0.088	0.844	0.068	0.0
03	0.381	0.202	0.231	0.186
04	0.001	0.988	0.002	0.009
05	0.701	0.174	0.081	0.044
06	0.045	0.047	0.906	0.002
07	0.002	0.944	0.0	0.054
08	0.601	0.001	0.392	0.006
09	0.002	0.002	0.981	0.015
10	0.0	0.002	0.997	0.001
11	0.182	0.026	0.702	0.09
12	0.06	0.022	0.881	0.037
13	0.03	0.024	0.888	0.058
14	0.004	0.46	0.132	0.404
15	0.112	0.635	0.213	0.04

PWM

	A	C	G	T
01	-0.202	-0.858	0.604	-0.074
02	-1.032	1.212	-1.284	-4.982
03	0.419	-0.212	-0.078	-0.293
04	-4.525	1.369	-4.213	-3.156
05	1.027	-0.359	-1.113	-1.706
06	-1.684	-1.642	1.283	-4.213
07	-4.213	1.324	-4.982	-1.508
08	0.873	-4.525	0.447	-3.484
09	-4.213	-4.213	1.362	-2.711
10	-4.982	-4.213	1.378	-4.525
11	-0.315	-2.206	1.028	-1.01
12	-1.406	-2.362	1.255	-1.872
13	-2.071	-2.281	1.263	-1.439
14	-3.783	0.607	-0.633	0.477
15	-0.795	0.928	-0.159	-1.797

Standard thresholds

P-value	Threshold
0.001	1.99106
0.0005	3.32206
0.0001	6.08701