ZIC5.H12CORE.2.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZIC5.H12CORE.2.S.C
Gene (human)	ZIC5 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Zic5
Gene synonyms (mouse)	Opr
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	C

Motif length	17
Consensus	ndMdCAGCGGGGGGTMn
GC content	73.4%
Information content (bits; total / per base)	20.217 / 1.189
Data sources	HT-SELEX
Aligned words	4465

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (61)	0.856	0.946	0.79	0.92	0.794	0.913	2.815	4.047	295.167	476.143

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.961	0.963	0.787	0.812	0.632	0.681
Overall, 2 experiments	best	0.999	0.999	0.875	0.891	0.675	0.729
Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.875	0.891	0.675	0.729
Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.875	0.891	0.675	0.729
Non-Methyl HT-SELEX, 1 experiments	median	0.922	0.928	0.699	0.734	0.589	0.632
Non-Methyl HT-SELEX, 1 experiments	best	0.922	0.928	0.699	0.734	0.589	0.632

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.11
HGNC	HGNC:20322
MGI	MGI:1929518
EntrezGene (human)	GeneID:85416 (SSTAR profile)
EntrezGene (mouse)	GeneID:65100 (SSTAR profile)
UniProt ID (human)	ZIC5_HUMAN
UniProt ID (mouse)	ZIC5_MOUSE
UniProt AC (human)	Q96T25 (TFClass)
UniProt AC (mouse)	Q7TQ40 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZIC5.H12CORE.2.S.C.pcm
PWM	ZIC5.H12CORE.2.S.C.pwm
PFM	ZIC5.H12CORE.2.S.C.pfm
Alignment	ZIC5.H12CORE.2.S.C.words.tsv
Threshold to P-value map	ZIC5.H12CORE.2.S.C.thr
Motif in other formats
JASPAR format	ZIC5.H12CORE.2.S.C_jaspar_format.txt
MEME format	ZIC5.H12CORE.2.S.C_meme_format.meme
Transfac format	ZIC5.H12CORE.2.S.C_transfac_format.txt
Homer format	ZIC5.H12CORE.2.S.C_homer_format_0.001.txt ZIC5.H12CORE.2.S.C_homer_format_0.0005.txt ZIC5.H12CORE.2.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	930.75	980.75	1304.75	1248.75
02	926.0	178.0	1792.0	1569.0
03	630.0	3314.0	468.0	53.0
04	1527.0	214.0	1826.0	898.0
05	32.0	4266.0	85.0	82.0
06	3743.0	195.0	303.0	224.0
07	484.0	2.0	3978.0	1.0
08	14.0	4262.0	74.0	115.0
09	302.0	1.0	4161.0	1.0
10	5.0	9.0	4436.0	15.0
11	27.0	0.0	4435.0	3.0
12	89.0	4.0	4287.0	85.0
13	8.0	7.0	4441.0	9.0
14	9.0	0.0	4408.0	48.0
15	51.0	259.0	315.0	3840.0
16	1116.0	2607.0	638.0	104.0
17	858.0	1082.0	1383.0	1142.0

PFM

	A	C	G	T
01	0.208	0.22	0.292	0.28
02	0.207	0.04	0.401	0.351
03	0.141	0.742	0.105	0.012
04	0.342	0.048	0.409	0.201
05	0.007	0.955	0.019	0.018
06	0.838	0.044	0.068	0.05
07	0.108	0.0	0.891	0.0
08	0.003	0.955	0.017	0.026
09	0.068	0.0	0.932	0.0
10	0.001	0.002	0.994	0.003
11	0.006	0.0	0.993	0.001
12	0.02	0.001	0.96	0.019
13	0.002	0.002	0.995	0.002
14	0.002	0.0	0.987	0.011
15	0.011	0.058	0.071	0.86
16	0.25	0.584	0.143	0.023
17	0.192	0.242	0.31	0.256

PWM

	A	C	G	T
01	-0.181	-0.129	0.156	0.112
02	-0.186	-1.826	0.473	0.34
03	-0.571	1.087	-0.867	-3.01
04	0.313	-1.644	0.491	-0.217
05	-3.49	1.339	-2.553	-2.588
06	1.209	-1.736	-1.299	-1.599
07	-0.833	-5.608	1.269	-5.888
08	-4.241	1.338	-2.688	-2.257
09	-1.302	-5.888	1.314	-5.888
10	-5.059	-4.613	1.378	-4.18
11	-3.649	-6.277	1.378	-5.39
12	-2.508	-5.211	1.344	-2.553
13	-4.707	-4.811	1.379	-4.613
14	-4.613	-6.277	1.372	-3.106
15	-3.047	-1.455	-1.26	1.234
16	-0.0	0.847	-0.558	-2.355
17	-0.263	-0.031	0.214	0.023

Standard thresholds

P-value	Threshold
0.001	-1.40144
0.0005	0.28281
0.0001	3.81601