MotifZIC4.H12INVIVO.0.SM.D
Gene (human)ZIC4
(GeneCards)
Gene synonyms (human)
Gene (mouse)Zic4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length15
ConsensusdvdYvGYRGGGGGKn
GC content66.3%
Information content (bits; total / per base)12.026 / 0.802
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9863

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.992 0.987 0.931 0.929 0.742 0.775
best 0.995 0.994 0.987 0.979 0.973 0.961
Methyl HT-SELEX, 1 experiments median 0.992 0.987 0.987 0.979 0.973 0.961
best 0.992 0.987 0.987 0.979 0.973 0.961
Non-Methyl HT-SELEX, 2 experiments median 0.942 0.932 0.83 0.83 0.68 0.707
best 0.995 0.994 0.931 0.929 0.742 0.775

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.869 0.642 0.867 0.635
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.10
HGNCHGNC:20393
MGIMGI:107201
EntrezGene (human)GeneID:84107
(SSTAR profile)
EntrezGene (mouse)GeneID:22774
(SSTAR profile)
UniProt ID (human)ZIC4_HUMAN
UniProt ID (mouse)ZIC4_MOUSE
UniProt AC (human)Q8N9L1
(TFClass)
UniProt AC (mouse)Q61467
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
PCM
ACGT
012112.01263.03304.03184.0
023151.04422.01687.0603.0
034938.0751.01795.02379.0
04651.07352.0349.01511.0
055514.01954.01483.0912.0
061608.0207.07877.0171.0
07263.06170.0892.02538.0
084541.01.05269.052.0
0933.07.08822.01001.0
104.012.09837.010.0
11817.085.08140.0821.0
12375.0249.08615.0624.0
13579.0107.08076.01101.0
14209.751652.751939.756060.75
152478.03242.02522.01621.0
PFM
ACGT
010.2140.1280.3350.323
020.3190.4480.1710.061
030.5010.0760.1820.241
040.0660.7450.0350.153
050.5590.1980.150.092
060.1630.0210.7990.017
070.0270.6260.090.257
080.460.00.5340.005
090.0030.0010.8940.101
100.00.0010.9970.001
110.0830.0090.8250.083
120.0380.0250.8730.063
130.0590.0110.8190.112
140.0210.1680.1970.614
150.2510.3290.2560.164
PWM
ACGT
01-0.155-0.6680.2920.255
020.2450.584-0.379-1.405
030.694-1.187-0.317-0.036
04-1.3291.092-1.95-0.489
050.804-0.232-0.508-0.993
06-0.427-2.4671.161-2.656
07-2.230.917-1.0150.029
080.61-6.6180.759-3.817
09-4.247-5.5811.274-0.9
10-5.971-5.1511.383-5.302
11-1.103-3.3421.194-1.098
12-1.878-2.2851.25-1.371
13-1.446-3.1171.186-0.805
14-2.454-0.4-0.240.899
150.0050.2730.023-0.419
Standard thresholds
P-value Threshold
0.001 4.15756
0.0005 5.16206
0.0001 7.18271