MotifZIC3.H12INVIVO.1.S.B
Gene (human)ZIC3
(GeneCards)
Gene synonyms (human)ZNF203
Gene (mouse)Zic3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusdMdCAGCGGGGGGYvnnn
GC content67.35%
Information content (bits; total / per base)17.897 / 0.994
Data sourcesHT-SELEX
Aligned words8349

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 4 (27) 0.844 0.911 0.707 0.832 0.762 0.866 2.14 2.979 78.699 258.056

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.743 0.764 0.607 0.635 0.553 0.577
best 1.0 0.999 0.999 0.999 0.997 0.996
Methyl HT-SELEX, 2 experiments median 0.81 0.823 0.777 0.786 0.764 0.769
best 1.0 0.999 0.999 0.999 0.997 0.996
Non-Methyl HT-SELEX, 4 experiments median 0.743 0.764 0.607 0.635 0.553 0.577
best 0.999 0.998 0.998 0.997 0.995 0.993

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.936 0.095 0.825 0.433
batch 2 0.787 0.575 0.627 0.424
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.9
HGNCHGNC:12874
MGIMGI:106676
EntrezGene (human)GeneID:7547
(SSTAR profile)
EntrezGene (mouse)GeneID:22773
(SSTAR profile)
UniProt ID (human)ZIC3_HUMAN
UniProt ID (mouse)ZIC3_MOUSE
UniProt AC (human)O60481
(TFClass)
UniProt AC (mouse)Q62521
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 4 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012548.0664.02362.02775.0
021737.255917.25462.25232.25
034488.0846.01962.01053.0
0430.08223.012.084.0
057297.0534.099.0419.0
06460.029.07859.01.0
0718.08158.018.0155.0
082411.00.05935.03.0
090.025.08299.025.0
108.04.08324.013.0
11515.08.07302.0524.0
12142.0166.07515.0526.0
13336.053.07399.0561.0
14132.02061.01366.04790.0
152108.04246.01230.0765.0
162176.01607.01661.02905.0
172335.01675.01645.02694.0
182252.01710.01842.02545.0
PFM
ACGT
010.3050.080.2830.332
020.2080.7090.0550.028
030.5380.1010.2350.126
040.0040.9850.0010.01
050.8740.0640.0120.05
060.0550.0030.9410.0
070.0020.9770.0020.019
080.2890.00.7110.0
090.00.0030.9940.003
100.0010.00.9970.002
110.0620.0010.8750.063
120.0170.020.90.063
130.040.0060.8860.067
140.0160.2470.1640.574
150.2520.5090.1470.092
160.2610.1920.1990.348
170.280.2010.1970.323
180.270.2050.2210.305
PWM
ACGT
010.199-1.1430.1240.285
02-0.1831.041-1.504-2.187
030.765-0.901-0.062-0.683
04-4.1711.37-4.987-3.187
051.251-1.36-3.027-1.601
06-1.509-4.2021.325-6.464
07-4.6361.362-4.636-2.587
080.144-6.831.044-5.985
09-6.83-4.3391.379-4.339
10-5.317-5.8111.382-4.92
11-1.396-5.3171.252-1.379
12-2.673-2.5191.28-1.375
13-1.821-3.6331.265-1.311
14-2.745-0.013-0.4230.83
150.010.71-0.528-1.002
160.042-0.261-0.2280.33
170.112-0.22-0.2380.255
180.076-0.199-0.1250.198
Standard thresholds
P-value Threshold
0.001 0.39381
0.0005 1.94831
0.0001 5.17466