ZIC2.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZIC2.H12INVIVO.0.P.B
Gene (human)	ZIC2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Zic2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	dChCMGCAGGdRdbh
GC content	64.3%
Information content (bits; total / per base)	12.827 / 0.855
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.862	0.907	0.78	0.807	0.812	0.868	2.725	3.009	130.406	242.959
Mouse	4 (28)	0.892	0.949	0.781	0.892	0.823	0.877	2.59	3.495	109.377	308.959

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.8
HGNC	HGNC:12873
MGI	MGI:106679
EntrezGene (human)	GeneID:7546 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZIC2_HUMAN
UniProt ID (mouse)	ZIC2_MOUSE
UniProt AC (human)	O95409 (TFClass)
UniProt AC (mouse)	Q62520 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	ZIC2.H12INVIVO.0.P.B.pcm
PWM	ZIC2.H12INVIVO.0.P.B.pwm
PFM	ZIC2.H12INVIVO.0.P.B.pfm
Alignment	ZIC2.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	ZIC2.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	ZIC2.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	ZIC2.H12INVIVO.0.P.B_meme_format.meme
Transfac format	ZIC2.H12INVIVO.0.P.B_transfac_format.txt
Homer format	ZIC2.H12INVIVO.0.P.B_homer_format_0.001.txt ZIC2.H12INVIVO.0.P.B_homer_format_0.0005.txt ZIC2.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	194.0	96.0	295.0	414.0
02	107.0	853.0	33.0	6.0
03	318.0	230.0	73.0	378.0
04	1.0	982.0	4.0	12.0
05	756.0	119.0	22.0	102.0
06	58.0	101.0	831.0	9.0
07	4.0	894.0	24.0	77.0
08	801.0	3.0	150.0	45.0
09	27.0	0.0	909.0	63.0
10	4.0	3.0	989.0	3.0
11	291.0	80.0	406.0	222.0
12	350.0	61.0	519.0	69.0
13	143.0	122.0	571.0	163.0
14	56.0	521.0	189.0	233.0
15	264.0	416.0	140.0	179.0

PFM

	A	C	G	T
01	0.194	0.096	0.295	0.414
02	0.107	0.854	0.033	0.006
03	0.318	0.23	0.073	0.378
04	0.001	0.983	0.004	0.012
05	0.757	0.119	0.022	0.102
06	0.058	0.101	0.832	0.009
07	0.004	0.895	0.024	0.077
08	0.802	0.003	0.15	0.045
09	0.027	0.0	0.91	0.063
10	0.004	0.003	0.99	0.003
11	0.291	0.08	0.406	0.222
12	0.35	0.061	0.52	0.069
13	0.143	0.122	0.572	0.163
14	0.056	0.522	0.189	0.233
15	0.264	0.416	0.14	0.179

PWM

	A	C	G	T
01	-0.251	-0.945	0.165	0.503
02	-0.839	1.223	-1.98	-3.483
03	0.24	-0.082	-1.214	0.412
04	-4.524	1.364	-3.782	-2.908
05	1.103	-0.734	-2.361	-0.886
06	-1.438	-0.895	1.197	-3.155
07	-3.782	1.27	-2.28	-1.161
08	1.161	-3.974	-0.505	-1.683
09	-2.17	-4.981	1.287	-1.357
10	-3.782	-3.974	1.371	-3.974
11	0.152	-1.124	0.483	-0.117
12	0.336	-1.389	0.728	-1.269
13	-0.553	-0.709	0.823	-0.423
14	-1.472	0.732	-0.277	-0.069
15	0.055	0.507	-0.573	-0.33

Standard thresholds

P-value	Threshold
0.001	3.88851
0.0005	4.93901
0.0001	7.08406