MotifZIC1.H12INVIVO.1.M.B
Gene (human)ZIC1
(GeneCards)
Gene synonyms (human)ZIC, ZNF201
Gene (mouse)Zic1
Gene synonyms (mouse)Zic
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length16
ConsensusndMWCAGCAGGGGGYn
GC content65.94%
Information content (bits; total / per base)16.95 / 1.059
Data sourcesMethyl-HT-SELEX
Aligned words9998

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (14) 0.835 0.854 0.691 0.72 0.703 0.745 1.941 2.033 59.777 79.432

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.998 0.997 0.996 0.994 0.984 0.98
best 1.0 1.0 1.0 0.999 0.998 0.998
Methyl HT-SELEX, 2 experiments median 1.0 0.999 0.999 0.999 0.996 0.995
best 1.0 1.0 1.0 0.999 0.998 0.998
Non-Methyl HT-SELEX, 4 experiments median 0.926 0.928 0.831 0.843 0.777 0.791
best 0.999 0.998 0.998 0.996 0.992 0.989

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.929 0.396 0.923 0.583
batch 2 0.8 0.527 0.787 0.582
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.7
HGNCHGNC:12872
MGIMGI:106683
EntrezGene (human)GeneID:7545
(SSTAR profile)
EntrezGene (mouse)GeneID:22771
(SSTAR profile)
UniProt ID (human)ZIC1_HUMAN
UniProt ID (mouse)ZIC1_MOUSE
UniProt AC (human)Q15915
(TFClass)
UniProt AC (mouse)P46684
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012403.02895.02224.02476.0
022140.5807.53380.53669.5
032944.06526.0441.087.0
047109.0368.0750.01771.0
0570.09698.050.0180.0
068104.01401.0320.0173.0
07475.038.09475.010.0
0816.09378.0113.0491.0
097826.00.02151.021.0
107.016.09629.0346.0
1121.041.09910.026.0
12740.071.08518.0669.0
13459.0133.08792.0614.0
14622.0131.08108.01137.0
15146.52234.51929.55687.5
162572.03463.02485.01478.0
PFM
ACGT
010.240.290.2220.248
020.2140.0810.3380.367
030.2940.6530.0440.009
040.7110.0370.0750.177
050.0070.970.0050.018
060.8110.140.0320.017
070.0480.0040.9480.001
080.0020.9380.0110.049
090.7830.00.2150.002
100.0010.0020.9630.035
110.0020.0040.9910.003
120.0740.0070.8520.067
130.0460.0130.8790.061
140.0620.0130.8110.114
150.0150.2230.1930.569
160.2570.3460.2490.148
PWM
ACGT
01-0.0390.147-0.117-0.009
02-0.155-1.1280.3020.384
030.1640.959-1.731-3.333
041.045-1.91-1.202-0.344
05-3.5441.355-3.868-2.619
061.176-0.578-2.049-2.658
07-1.657-4.1281.332-5.315
08-4.9181.322-3.077-1.624
091.141-6.991-0.15-4.676
10-5.594-4.9181.348-1.972
11-4.676-4.0571.377-4.482
12-1.215-3.531.225-1.316
13-1.691-2.9171.257-1.401
14-1.388-2.9321.176-0.787
15-2.822-0.112-0.2590.822
160.0290.326-0.006-0.525
Standard thresholds
P-value Threshold
0.001 1.51286
0.0005 2.89781
0.0001 5.77656