MotifZIC1.H12INVITRO.0.P.B
Gene (human)ZIC1
(GeneCards)
Gene synonyms (human)ZIC, ZNF201
Gene (mouse)Zic1
Gene synonyms (mouse)Zic
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusdCnCMGCRGG
GC content74.09%
Information content (bits; total / per base)11.166 / 1.117
Data sourcesChIP-Seq
Aligned words996

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (14) 0.874 0.885 0.753 0.776 0.772 0.808 2.235 2.461 110.21 127.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.985 0.974 0.974 0.958 0.951 0.935
best 0.993 0.985 0.985 0.976 0.965 0.951
Methyl HT-SELEX, 2 experiments median 0.99 0.981 0.98 0.968 0.956 0.94
best 0.993 0.985 0.985 0.976 0.964 0.951
Non-Methyl HT-SELEX, 4 experiments median 0.896 0.887 0.81 0.81 0.76 0.767
best 0.992 0.985 0.983 0.974 0.965 0.943

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.784 0.277 0.752 0.466
batch 2 0.665 0.356 0.573 0.422
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyGLI-lile {2.3.3.1} (TFClass)
TFClass IDTFClass: 2.3.3.1.7
HGNCHGNC:12872
MGIMGI:106683
EntrezGene (human)GeneID:7545
(SSTAR profile)
EntrezGene (mouse)GeneID:22771
(SSTAR profile)
UniProt ID (human)ZIC1_HUMAN
UniProt ID (mouse)ZIC1_MOUSE
UniProt AC (human)Q15915
(TFClass)
UniProt AC (mouse)P46684
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01143.0112.0530.0211.0
0296.0870.020.010.0
03264.0216.0288.0228.0
046.0983.04.03.0
05701.0142.033.0120.0
0623.032.0939.02.0
0721.0930.010.035.0
08524.02.0438.032.0
0918.010.0860.0108.0
1020.08.0952.016.0
PFM
ACGT
010.1440.1120.5320.212
020.0960.8730.020.01
030.2650.2170.2890.229
040.0060.9870.0040.003
050.7040.1430.0330.12
060.0230.0320.9430.002
070.0210.9340.010.035
080.5260.0020.440.032
090.0180.010.8630.108
100.020.0080.9560.016
PWM
ACGT
01-0.55-0.7910.752-0.164
02-0.9421.246-2.446-3.063
030.058-0.1410.145-0.087
04-3.481.368-3.779-3.971
051.031-0.556-1.977-0.723
06-2.317-2.0061.322-4.209
07-2.4011.313-3.063-1.921
080.74-4.2090.562-2.006
09-2.542-3.0631.235-0.826
10-2.446-3.251.336-2.649
Standard thresholds
P-value Threshold
0.001 4.41482
0.0005 5.304205
0.0001 7.251415