ZIC1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZIC1.H12CORE.0.P.B
Gene (human)	ZIC1 (GeneCards)
Gene synonyms (human)	ZIC, ZNF201
Gene (mouse)	Zic1
Gene synonyms (mouse)	Zic
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	dCnCMGCRGG
GC content	74.09%
Information content (bits; total / per base)	11.166 / 1.117
Data sources	ChIP-Seq
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	2 (14)	0.874	0.885	0.753	0.776	0.772	0.808	2.235	2.461	110.21	127.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.985	0.974	0.974	0.958	0.951	0.935
Overall, 6 experiments	best	0.993	0.985	0.985	0.976	0.965	0.951
Methyl HT-SELEX, 2 experiments	median	0.99	0.981	0.98	0.968	0.956	0.94
Methyl HT-SELEX, 2 experiments	best	0.993	0.985	0.985	0.976	0.964	0.951
Non-Methyl HT-SELEX, 4 experiments	median	0.896	0.887	0.81	0.81	0.76	0.767
Non-Methyl HT-SELEX, 4 experiments	best	0.992	0.985	0.983	0.974	0.965	0.943

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.784	0.277	0.752	0.466
batch 2	0.665	0.356	0.573	0.422

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	GLI-lile {2.3.3.1} (TFClass)
TFClass ID	TFClass: 2.3.3.1.7
HGNC	HGNC:12872
MGI	MGI:106683
EntrezGene (human)	GeneID:7545 (SSTAR profile)
EntrezGene (mouse)	GeneID:22771 (SSTAR profile)
UniProt ID (human)	ZIC1_HUMAN
UniProt ID (mouse)	ZIC1_MOUSE
UniProt AC (human)	Q15915 (TFClass)
UniProt AC (mouse)	P46684 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 2 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	ZIC1.H12CORE.0.P.B.pcm
PWM	ZIC1.H12CORE.0.P.B.pwm
PFM	ZIC1.H12CORE.0.P.B.pfm
Alignment	ZIC1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	ZIC1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	ZIC1.H12CORE.0.P.B_jaspar_format.txt
MEME format	ZIC1.H12CORE.0.P.B_meme_format.meme
Transfac format	ZIC1.H12CORE.0.P.B_transfac_format.txt
Homer format	ZIC1.H12CORE.0.P.B_homer_format_0.001.txt ZIC1.H12CORE.0.P.B_homer_format_0.0005.txt ZIC1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	143.0	112.0	530.0	211.0
02	96.0	870.0	20.0	10.0
03	264.0	216.0	288.0	228.0
04	6.0	983.0	4.0	3.0
05	701.0	142.0	33.0	120.0
06	23.0	32.0	939.0	2.0
07	21.0	930.0	10.0	35.0
08	524.0	2.0	438.0	32.0
09	18.0	10.0	860.0	108.0
10	20.0	8.0	952.0	16.0

PFM

	A	C	G	T
01	0.144	0.112	0.532	0.212
02	0.096	0.873	0.02	0.01
03	0.265	0.217	0.289	0.229
04	0.006	0.987	0.004	0.003
05	0.704	0.143	0.033	0.12
06	0.023	0.032	0.943	0.002
07	0.021	0.934	0.01	0.035
08	0.526	0.002	0.44	0.032
09	0.018	0.01	0.863	0.108
10	0.02	0.008	0.956	0.016

PWM

	A	C	G	T
01	-0.55	-0.791	0.752	-0.164
02	-0.942	1.246	-2.446	-3.063
03	0.058	-0.141	0.145	-0.087
04	-3.48	1.368	-3.779	-3.971
05	1.031	-0.556	-1.977	-0.723
06	-2.317	-2.006	1.322	-4.209
07	-2.401	1.313	-3.063	-1.921
08	0.74	-4.209	0.562	-2.006
09	-2.542	-3.063	1.235	-0.826
10	-2.446	-3.25	1.336	-2.649

Standard thresholds

P-value	Threshold
0.001	4.41482
0.0005	5.304205
0.0001	7.251415