ZFP42.H12INVITRO.0.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZFP42.H12INVITRO.0.PM.A
Gene (human)	ZFP42 (GeneCards)
Gene synonyms (human)	REX1, ZNF754
Gene (mouse)	Zfp42
Gene synonyms (mouse)	Rex-1, Rex1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	RRSMGCCATYTTd
GC content	50.19%
Information content (bits; total / per base)	13.939 / 1.072
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	875

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.841	0.869	0.819	0.852	0.784	0.82	3.721	4.129	278.328	339.678

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.979	0.974	0.814	0.822	0.677	0.701
Methyl HT-SELEX, 1 experiments	best	0.979	0.974	0.814	0.822	0.677	0.701

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	YY1-like {2.3.3.9} (TFClass)
TFClass ID	TFClass: 2.3.3.9.3
HGNC	HGNC:30949
MGI	MGI:99187
EntrezGene (human)	GeneID:132625 (SSTAR profile)
EntrezGene (mouse)	GeneID:22702 (SSTAR profile)
UniProt ID (human)	ZFP42_HUMAN
UniProt ID (mouse)	ZFP42_MOUSE
UniProt AC (human)	Q96MM3 (TFClass)
UniProt AC (mouse)	P22227 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	1

PCM	ZFP42.H12INVITRO.0.PM.A.pcm
PWM	ZFP42.H12INVITRO.0.PM.A.pwm
PFM	ZFP42.H12INVITRO.0.PM.A.pfm
Alignment	ZFP42.H12INVITRO.0.PM.A.words.tsv
Threshold to P-value map	ZFP42.H12INVITRO.0.PM.A.thr
Motif in other formats
JASPAR format	ZFP42.H12INVITRO.0.PM.A_jaspar_format.txt
MEME format	ZFP42.H12INVITRO.0.PM.A_meme_format.meme
Transfac format	ZFP42.H12INVITRO.0.PM.A_transfac_format.txt
Homer format	ZFP42.H12INVITRO.0.PM.A_homer_format_0.001.txt ZFP42.H12INVITRO.0.PM.A_homer_format_0.0005.txt ZFP42.H12INVITRO.0.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	211.0	62.0	529.0	73.0
02	120.0	39.0	667.0	49.0
03	118.0	536.0	187.0	34.0
04	558.0	212.0	62.0	43.0
05	18.0	11.0	755.0	91.0
06	91.0	739.0	17.0	28.0
07	0.0	869.0	2.0	4.0
08	874.0	1.0	0.0	0.0
09	0.0	2.0	1.0	872.0
10	39.0	193.0	88.0	555.0
11	41.0	51.0	46.0	737.0
12	23.0	102.0	15.0	735.0
13	139.0	104.0	419.0	213.0

PFM

	A	C	G	T
01	0.241	0.071	0.605	0.083
02	0.137	0.045	0.762	0.056
03	0.135	0.613	0.214	0.039
04	0.638	0.242	0.071	0.049
05	0.021	0.013	0.863	0.104
06	0.104	0.845	0.019	0.032
07	0.0	0.993	0.002	0.005
08	0.999	0.001	0.0	0.0
09	0.0	0.002	0.001	0.997
10	0.045	0.221	0.101	0.634
11	0.047	0.058	0.053	0.842
12	0.026	0.117	0.017	0.84
13	0.159	0.119	0.479	0.243

PWM

	A	C	G	T
01	-0.036	-1.242	0.879	-1.082
02	-0.594	-1.69	1.11	-1.47
03	-0.611	0.892	-0.156	-1.821
04	0.932	-0.031	-1.242	-1.596
05	-2.415	-2.855	1.233	-0.866
06	-0.866	1.212	-2.467	-2.005
07	-4.869	1.374	-4.089	-3.656
08	1.379	-4.405	-4.869	-4.869
09	-4.869	-4.089	-4.405	1.377
10	-1.69	-0.124	-0.899	0.926
11	-1.642	-1.431	-1.531	1.209
12	-2.189	-0.754	-2.581	1.207
13	-0.449	-0.735	0.646	-0.026

Standard thresholds

P-value	Threshold
0.001	3.42996
0.0005	4.577915
0.0001	6.902785