ZFP42.H12CORE.0.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZFP42.H12CORE.0.PM.A
Gene (human)	ZFP42 (GeneCards)
Gene synonyms (human)	REX1, ZNF754
Gene (mouse)	Zfp42
Gene synonyms (mouse)	Rex-1, Rex1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	RRSMGCCATYTTd
GC content	51.45%
Information content (bits; total / per base)	14.357 / 1.104
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	842

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.839	0.87	0.818	0.853	0.78	0.819	3.735	4.184	282.921	348.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.979	0.974	0.813	0.822	0.673	0.7
Methyl HT-SELEX, 1 experiments	best	0.979	0.974	0.813	0.822	0.673	0.7

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	YY1-like {2.3.3.9} (TFClass)
TFClass ID	TFClass: 2.3.3.9.3
HGNC	HGNC:30949
MGI	MGI:99187
EntrezGene (human)	GeneID:132625 (SSTAR profile)
EntrezGene (mouse)	GeneID:22702 (SSTAR profile)
UniProt ID (human)	ZFP42_HUMAN
UniProt ID (mouse)	ZFP42_MOUSE
UniProt AC (human)	Q96MM3 (TFClass)
UniProt AC (mouse)	P22227 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	1

PCM	ZFP42.H12CORE.0.PM.A.pcm
PWM	ZFP42.H12CORE.0.PM.A.pwm
PFM	ZFP42.H12CORE.0.PM.A.pfm
Alignment	ZFP42.H12CORE.0.PM.A.words.tsv
Threshold to P-value map	ZFP42.H12CORE.0.PM.A.thr
Motif in other formats
JASPAR format	ZFP42.H12CORE.0.PM.A_jaspar_format.txt
MEME format	ZFP42.H12CORE.0.PM.A_meme_format.meme
Transfac format	ZFP42.H12CORE.0.PM.A_transfac_format.txt
Homer format	ZFP42.H12CORE.0.PM.A_homer_format_0.001.txt ZFP42.H12CORE.0.PM.A_homer_format_0.0005.txt ZFP42.H12CORE.0.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	182.0	87.0	499.0	74.0
02	95.0	36.0	666.0	45.0
03	82.0	535.0	196.0	29.0
04	505.0	256.0	60.0	21.0
05	13.0	10.0	742.0	77.0
06	65.0	745.0	16.0	16.0
07	1.0	838.0	1.0	2.0
08	840.0	1.0	1.0	0.0
09	1.0	0.0	0.0	841.0
10	40.0	183.0	75.0	544.0
11	55.0	38.0	36.0	713.0
12	14.0	102.0	16.0	710.0
13	141.0	105.0	388.0	208.0

PFM

	A	C	G	T
01	0.216	0.103	0.593	0.088
02	0.113	0.043	0.791	0.053
03	0.097	0.635	0.233	0.034
04	0.6	0.304	0.071	0.025
05	0.015	0.012	0.881	0.091
06	0.077	0.885	0.019	0.019
07	0.001	0.995	0.001	0.002
08	0.998	0.001	0.001	0.0
09	0.001	0.0	0.0	0.999
10	0.048	0.217	0.089	0.646
11	0.065	0.045	0.043	0.847
12	0.017	0.121	0.019	0.843
13	0.167	0.125	0.461	0.247

PWM

	A	C	G	T
01	-0.144	-0.872	0.859	-1.031
02	-0.786	-1.728	1.146	-1.514
03	-0.93	0.928	-0.071	-1.934
04	0.87	0.194	-1.235	-2.236
05	-2.671	-2.899	1.254	-0.992
06	-1.157	1.258	-2.485	-2.485
07	-4.37	1.376	-4.37	-4.053
08	1.378	-4.37	-4.37	-4.836
09	-4.37	-4.836	-4.836	1.379
10	-1.627	-0.139	-1.018	0.945
11	-1.32	-1.677	-1.728	1.214
12	-2.605	-0.716	-2.485	1.21
13	-0.397	-0.688	0.608	-0.012

Standard thresholds

P-value	Threshold
0.001	3.19951
0.0005	4.38756
0.0001	6.7946