ZFP1.H12INVIVO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZFP1.H12INVIVO.0.PSM.A
Gene (human)	ZFP1 (GeneCards)
Gene synonyms (human)	ZNF475
Gene (mouse)	Zfp1
Gene synonyms (mouse)	Fnp-1, Zfp-1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	23
Consensus	YWYYRYhYCCWGShMhvbYvdSh
GC content	47.4%
Information content (bits; total / per base)	12.933 / 0.562
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (9)	0.665	0.853	0.633	0.872	0.693	0.857	5.11	10.965	37.086	95.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.991	0.989	0.921	0.922	0.805	0.821
Overall, 2 experiments	best	0.999	0.999	0.994	0.992	0.925	0.925
Methyl HT-SELEX, 1 experiments	median	0.999	0.999	0.994	0.992	0.925	0.925
Methyl HT-SELEX, 1 experiments	best	0.999	0.999	0.994	0.992	0.925	0.925
Non-Methyl HT-SELEX, 1 experiments	median	0.984	0.98	0.848	0.851	0.684	0.717
Non-Methyl HT-SELEX, 1 experiments	best	0.984	0.98	0.848	0.851	0.684	0.717

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	Unclassified {2.3.3.0} (TFClass)
TFClass ID	TFClass: 2.3.3.0.72
HGNC	HGNC:23328
MGI	MGI:99154
EntrezGene (human)	GeneID:162239 (SSTAR profile)
EntrezGene (mouse)	GeneID:22640 (SSTAR profile)
UniProt ID (human)	ZFP1_HUMAN
UniProt ID (mouse)	ZFP1_MOUSE
UniProt AC (human)	Q6P2D0 (TFClass)
UniProt AC (mouse)	P08042 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZFP1.H12INVIVO.0.PSM.A.pcm
PWM	ZFP1.H12INVIVO.0.PSM.A.pwm
PFM	ZFP1.H12INVIVO.0.PSM.A.pfm
Alignment	ZFP1.H12INVIVO.0.PSM.A.words.tsv
Threshold to P-value map	ZFP1.H12INVIVO.0.PSM.A.thr
Motif in other formats
JASPAR format	ZFP1.H12INVIVO.0.PSM.A_jaspar_format.txt
MEME format	ZFP1.H12INVIVO.0.PSM.A_meme_format.meme
Transfac format	ZFP1.H12INVIVO.0.PSM.A_transfac_format.txt
Homer format	ZFP1.H12INVIVO.0.PSM.A_homer_format_0.001.txt ZFP1.H12INVIVO.0.PSM.A_homer_format_0.0005.txt ZFP1.H12INVIVO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	42.0	180.0	56.0	722.0
02	115.0	102.0	71.0	712.0
03	47.0	345.0	104.0	504.0
04	93.0	302.0	66.0	539.0
05	623.0	96.0	183.0	98.0
06	72.0	176.0	93.0	659.0
07	592.0	141.0	100.0	167.0
08	90.0	704.0	88.0	118.0
09	41.0	883.0	23.0	53.0
10	40.0	853.0	14.0	93.0
11	729.0	36.0	53.0	182.0
12	67.0	70.0	834.0	29.0
13	69.0	759.0	96.0	76.0
14	256.0	349.0	75.0	320.0
15	504.0	335.0	136.0	25.0
16	580.0	184.0	66.0	170.0
17	546.0	130.0	195.0	129.0
18	148.0	523.0	162.0	167.0
19	104.0	146.0	94.0	656.0
20	473.0	150.0	265.0	112.0
21	212.0	180.0	186.0	422.0
22	80.0	681.0	143.0	96.0
23	323.0	413.0	61.0	203.0

PFM

	A	C	G	T
01	0.042	0.18	0.056	0.722
02	0.115	0.102	0.071	0.712
03	0.047	0.345	0.104	0.504
04	0.093	0.302	0.066	0.539
05	0.623	0.096	0.183	0.098
06	0.072	0.176	0.093	0.659
07	0.592	0.141	0.1	0.167
08	0.09	0.704	0.088	0.118
09	0.041	0.883	0.023	0.053
10	0.04	0.853	0.014	0.093
11	0.729	0.036	0.053	0.182
12	0.067	0.07	0.834	0.029
13	0.069	0.759	0.096	0.076
14	0.256	0.349	0.075	0.32
15	0.504	0.335	0.136	0.025
16	0.58	0.184	0.066	0.17
17	0.546	0.13	0.195	0.129
18	0.148	0.523	0.162	0.167
19	0.104	0.146	0.094	0.656
20	0.473	0.15	0.265	0.112
21	0.212	0.18	0.186	0.422
22	0.08	0.681	0.143	0.096
23	0.323	0.413	0.061	0.203

PWM

	A	C	G	T
01	-1.75	-0.326	-1.473	1.056
02	-0.769	-0.887	-1.242	1.042
03	-1.642	0.32	-0.867	0.698
04	-0.977	0.188	-1.313	0.765
05	0.909	-0.946	-0.309	-0.926
06	-1.228	-0.348	-0.977	0.965
07	0.858	-0.567	-0.906	-0.4
08	-1.01	1.031	-1.032	-0.743
09	-1.774	1.257	-2.32	-1.526
10	-1.797	1.222	-2.773	-0.977
11	1.066	-1.898	-1.526	-0.315
12	-1.298	-1.255	1.2	-2.103
13	-1.27	1.106	-0.946	-1.175
14	0.024	0.332	-1.188	0.245
15	0.698	0.291	-0.603	-2.243
16	0.838	-0.304	-1.313	-0.382
17	0.777	-0.648	-0.247	-0.655
18	-0.52	0.735	-0.43	-0.4
19	-0.867	-0.533	-0.967	0.96
20	0.634	-0.506	0.058	-0.795
21	-0.164	-0.326	-0.293	0.521
22	-1.125	0.998	-0.553	-0.946
23	0.255	0.499	-1.39	-0.207

Standard thresholds

P-value	Threshold
0.001	4.07761
0.0005	4.97071
0.0001	6.87691