ZBTB2.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBTB2.H12INVITRO.0.SM.B
Gene (human)	ZBTB2 (GeneCards)
Gene synonyms (human)	KIAA1483, ZNF437
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	nbYhCCGGTWvn
GC content	53.74%
Information content (bits; total / per base)	10.951 / 0.913
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9949

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.857	0.826	0.815	0.784	0.752	0.73
Overall, 2 experiments	best	0.976	0.964	0.949	0.929	0.883	0.861
Methyl HT-SELEX, 1 experiments	median	0.738	0.687	0.681	0.638	0.621	0.599
Methyl HT-SELEX, 1 experiments	best	0.738	0.687	0.681	0.638	0.621	0.599
Non-Methyl HT-SELEX, 1 experiments	median	0.976	0.964	0.949	0.929	0.883	0.861
Non-Methyl HT-SELEX, 1 experiments	best	0.976	0.964	0.949	0.929	0.883	0.861

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	ZBTB1-like {2.3.4.6} (TFClass)
TFClass ID	TFClass: 2.3.4.6.2
HGNC	HGNC:20868
MGI
EntrezGene (human)	GeneID:57621 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZBTB2_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q8N680 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZBTB2.H12INVITRO.0.SM.B.pcm
PWM	ZBTB2.H12INVITRO.0.SM.B.pwm
PFM	ZBTB2.H12INVITRO.0.SM.B.pfm
Alignment	ZBTB2.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	ZBTB2.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	ZBTB2.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	ZBTB2.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	ZBTB2.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	ZBTB2.H12INVITRO.0.SM.B_homer_format_0.001.txt ZBTB2.H12INVITRO.0.SM.B_homer_format_0.0005.txt ZBTB2.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2092.75	2094.75	2985.75	2775.75
02	1322.5	2337.5	2162.5	4126.5
03	929.0	2067.0	832.0	6121.0
04	2010.0	2621.0	718.0	4600.0
05	963.0	8651.0	2.0	333.0
06	0.0	9949.0	0.0	0.0
07	0.0	1.0	9948.0	0.0
08	0.0	2.0	9761.0	186.0
09	2.0	0.0	10.0	9937.0
10	6206.0	38.0	1269.0	2436.0
11	4797.5	2191.5	1488.5	1471.5
12	2785.25	3433.25	1599.25	2131.25

PFM

	A	C	G	T
01	0.21	0.211	0.3	0.279
02	0.133	0.235	0.217	0.415
03	0.093	0.208	0.084	0.615
04	0.202	0.263	0.072	0.462
05	0.097	0.87	0.0	0.033
06	0.0	1.0	0.0	0.0
07	0.0	0.0	1.0	0.0
08	0.0	0.0	0.981	0.019
09	0.0	0.0	0.001	0.999
10	0.624	0.004	0.128	0.245
11	0.482	0.22	0.15	0.148
12	0.28	0.345	0.161	0.214

PWM

	A	C	G	T
01	-0.173	-0.172	0.183	0.11
02	-0.631	-0.062	-0.14	0.506
03	-0.983	-0.185	-1.093	0.9
04	-0.213	0.052	-1.24	0.614
05	-0.947	1.246	-6.361	-2.005
06	-6.986	1.386	-6.986	-6.986
07	-6.986	-6.626	1.386	-6.986
08	-6.986	-6.361	1.367	-2.582
09	-6.361	-6.986	-5.31	1.384
10	0.914	-4.123	-0.672	-0.021
11	0.656	-0.126	-0.513	-0.524
12	0.113	0.322	-0.441	-0.154

Standard thresholds

P-value	Threshold
0.001	4.496735
0.0005	5.76901
0.0001	7.66171