ZBT7B.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT7B.H12INVIVO.0.SM.D
Gene (human)	ZBTB7B (GeneCards)
Gene synonyms (human)	ZBTB15, ZFP67, ZNF857B
Gene (mouse)	Zbtb7b
Gene synonyms (mouse)	Thpok, Zfp67
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	12
Consensus	dbGGTGGTCGhn
GC content	67.15%
Information content (bits; total / per base)	14.35 / 1.196
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	8003

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.97	0.959	0.929	0.903	0.841	0.818
Overall, 6 experiments	best	0.988	0.984	0.937	0.919	0.862	0.838
Methyl HT-SELEX, 2 experiments	median	0.962	0.943	0.931	0.902	0.86	0.832
Methyl HT-SELEX, 2 experiments	best	0.965	0.947	0.934	0.907	0.862	0.836
Non-Methyl HT-SELEX, 4 experiments	median	0.975	0.963	0.926	0.908	0.814	0.806
Non-Methyl HT-SELEX, 4 experiments	best	0.988	0.984	0.937	0.919	0.859	0.838

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZBTB7 {2.3.3.8} (TFClass)
TFClass ID	TFClass: 2.3.3.8.2
HGNC	HGNC:18668
MGI	MGI:102755
EntrezGene (human)	GeneID:51043 (SSTAR profile)
EntrezGene (mouse)	GeneID:22724 (SSTAR profile)
UniProt ID (human)	ZBT7B_HUMAN
UniProt ID (mouse)	ZBT7B_MOUSE
UniProt AC (human)	O15156 (TFClass)
UniProt AC (mouse)	Q64321 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	ZBT7B.H12INVIVO.0.SM.D.pcm
PWM	ZBT7B.H12INVIVO.0.SM.D.pwm
PFM	ZBT7B.H12INVIVO.0.SM.D.pfm
Alignment	ZBT7B.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	ZBT7B.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	ZBT7B.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	ZBT7B.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	ZBT7B.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	ZBT7B.H12INVIVO.0.SM.D_homer_format_0.001.txt ZBT7B.H12INVIVO.0.SM.D_homer_format_0.0005.txt ZBT7B.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1263.75	915.75	1923.75	3899.75
02	1455.5	3346.5	1639.5	1561.5
03	158.0	127.0	7559.0	159.0
04	16.0	6.0	7960.0	21.0
05	2.0	1.0	1412.0	6588.0
06	0.0	1.0	8002.0	0.0
07	0.0	0.0	8003.0	0.0
08	0.0	0.0	170.0	7833.0
09	37.0	7764.0	22.0	180.0
10	231.0	334.0	7058.0	380.0
11	2049.5	3551.5	476.5	1925.5
12	1956.5	2154.5	2064.5	1827.5

PFM

	A	C	G	T
01	0.158	0.114	0.24	0.487
02	0.182	0.418	0.205	0.195
03	0.02	0.016	0.945	0.02
04	0.002	0.001	0.995	0.003
05	0.0	0.0	0.176	0.823
06	0.0	0.0	1.0	0.0
07	0.0	0.0	1.0	0.0
08	0.0	0.0	0.021	0.979
09	0.005	0.97	0.003	0.022
10	0.029	0.042	0.882	0.047
11	0.256	0.444	0.06	0.241
12	0.244	0.269	0.258	0.228

PWM

	A	C	G	T
01	-0.459	-0.78	-0.039	0.667
02	-0.318	0.514	-0.199	-0.248
03	-2.526	-2.741	1.328	-2.519
04	-4.698	-5.493	1.38	-4.456
05	-6.156	-6.425	-0.348	1.191
06	-6.793	-6.425	1.385	-6.793
07	-6.793	-6.793	1.385	-6.793
08	-6.793	-6.793	-2.453	1.364
09	-3.933	1.355	-4.414	-2.397
10	-2.15	-1.785	1.26	-1.656
11	0.024	0.573	-1.431	-0.038
12	-0.022	0.074	0.031	-0.09

Standard thresholds

P-value	Threshold
0.001	1.93301
0.0005	3.41246
0.0001	6.62548