MotifZBT7A.H12INVIVO.1.SM.B
Gene (human)ZBTB7A
(GeneCards)
Gene synonyms (human)FBI1, LRF, ZBTB7, ZNF857A
Gene (mouse)Zbtb7a
Gene synonyms (mouse)Lrf, Zbtb7
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length16
ConsensusddddKdRGGGGTCKhv
GC content66.99%
Information content (bits; total / per base)14.06 / 0.879
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words833

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 9 (61) 0.727 0.793 0.521 0.606 0.655 0.769 1.611 2.097 55.796 121.42

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.932 0.891 0.899 0.853 0.822 0.787
best 0.937 0.898 0.9 0.855 0.834 0.794
Methyl HT-SELEX, 1 experiments median 0.937 0.898 0.897 0.855 0.809 0.78
best 0.937 0.898 0.897 0.855 0.809 0.78
Non-Methyl HT-SELEX, 1 experiments median 0.928 0.883 0.9 0.852 0.834 0.794
best 0.928 0.883 0.9 0.852 0.834 0.794

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.531 0.266 0.133 0.097
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyZBTB7 {2.3.3.8} (TFClass)
TFClass IDTFClass: 2.3.3.8.1
HGNCHGNC:18078
MGIMGI:1335091
EntrezGene (human)GeneID:51341
(SSTAR profile)
EntrezGene (mouse)GeneID:16969
(SSTAR profile)
UniProt ID (human)ZBT7A_HUMAN
UniProt ID (mouse)ZBT7A_MOUSE
UniProt AC (human)O95365
(TFClass)
UniProt AC (mouse)O88939
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 9 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01179.089.0317.0248.0
02138.588.5350.5255.5
03104.075.0490.0164.0
04158.092.0440.0143.0
05100.047.0536.0150.0
06144.080.0433.0176.0
07204.09.0584.036.0
0889.02.0737.05.0
090.00.0580.0253.0
100.00.0833.00.0
110.00.0833.00.0
120.00.011.0822.0
132.0824.00.07.0
1421.033.0447.0332.0
15150.25403.2561.25218.25
16170.25190.25343.25129.25
PFM
ACGT
010.2150.1070.3810.298
020.1660.1060.4210.307
030.1250.090.5880.197
040.190.110.5280.172
050.120.0560.6430.18
060.1730.0960.520.211
070.2450.0110.7010.043
080.1070.0020.8850.006
090.00.00.6960.304
100.00.01.00.0
110.00.01.00.0
120.00.00.0130.987
130.0020.9890.00.008
140.0250.040.5370.399
150.180.4840.0740.262
160.2040.2280.4120.155
PWM
ACGT
01-0.15-0.8390.4170.173
02-0.404-0.8450.5170.203
03-0.686-1.0070.851-0.237
04-0.274-0.8070.744-0.372
05-0.725-1.4610.94-0.325
06-0.365-0.9440.728-0.167
07-0.02-2.9781.026-1.718
08-0.839-4.0441.258-3.447
09-4.827-4.8271.0190.193
10-4.827-4.8271.38-4.827
11-4.827-4.8271.38-4.827
12-4.827-4.827-2.8071.367
13-4.0441.369-4.827-3.186
14-2.225-1.8010.760.463
15-0.3230.657-1.2050.047
16-0.2-0.090.497-0.472
Standard thresholds
P-value Threshold
0.001 2.92386
0.0005 4.22696
0.0001 6.97016