MotifZBT7A.H12INVIVO.0.P.B
Gene (human)ZBTB7A
(GeneCards)
Gene synonyms (human)FBI1, LRF, ZBTB7, ZNF857A
Gene (mouse)Zbtb7a
Gene synonyms (mouse)Lrf, Zbtb7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusvRGGGTCnY
GC content73.82%
Information content (bits; total / per base)10.642 / 1.182
Data sourcesChIP-Seq
Aligned words997

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 9 (61) 0.78 0.814 0.579 0.641 0.627 0.71 1.449 1.768 128.114 202.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.896 0.845 0.85 0.797 0.783 0.74
best 0.917 0.879 0.852 0.809 0.785 0.745
Methyl HT-SELEX, 1 experiments median 0.917 0.879 0.852 0.809 0.781 0.745
best 0.917 0.879 0.852 0.809 0.781 0.745
Non-Methyl HT-SELEX, 1 experiments median 0.875 0.811 0.848 0.784 0.785 0.734
best 0.875 0.811 0.848 0.784 0.785 0.734

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.633 1.288 0.151 0.126
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyZBTB7 {2.3.3.8} (TFClass)
TFClass IDTFClass: 2.3.3.8.1
HGNCHGNC:18078
MGIMGI:1335091
EntrezGene (human)GeneID:51341
(SSTAR profile)
EntrezGene (mouse)GeneID:16969
(SSTAR profile)
UniProt ID (human)ZBT7A_HUMAN
UniProt ID (mouse)ZBT7A_MOUSE
UniProt AC (human)O95365
(TFClass)
UniProt AC (mouse)O88939
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 9 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01265.0161.0491.080.0
02417.04.0570.06.0
031.00.0943.053.0
042.00.0995.00.0
053.01.0989.04.0
0618.00.0269.0710.0
0710.0982.02.03.0
0812.0267.0267.0451.0
0921.0572.0111.0293.0
PFM
ACGT
010.2660.1610.4920.08
020.4180.0040.5720.006
030.0010.00.9460.053
040.0020.00.9980.0
050.0030.0010.9920.004
060.0180.00.270.712
070.010.9850.0020.003
080.0120.2680.2680.452
090.0210.5740.1110.294
PWM
ACGT
010.061-0.4330.675-1.122
020.512-3.780.823-3.481
03-4.522-4.9791.326-1.523
04-4.21-4.9791.379-4.979
05-3.972-4.5221.373-3.78
06-2.543-4.9790.0761.042
07-3.0641.366-4.21-3.972
08-2.9060.0680.0680.59
09-2.4020.827-0.80.161
Standard thresholds
P-value Threshold
0.001 4.311815
0.0005 5.67073
0.0001 7.79424