ZBT7A.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT7A.H12INVITRO.0.P.B
Gene (human)	ZBTB7A (GeneCards)
Gene synonyms (human)	FBI1, LRF, ZBTB7, ZNF857A
Gene (mouse)	Zbtb7a
Gene synonyms (mouse)	Lrf, Zbtb7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	9
Consensus	vRGGGTCYY
GC content	71.84%
Information content (bits; total / per base)	11.142 / 1.238
Data sources	ChIP-Seq
Aligned words	1001

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (61)	0.762	0.798	0.559	0.625	0.653	0.729	1.536	1.841	108.252	174.745

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.899	0.84	0.86	0.802	0.782	0.742
Overall, 2 experiments	best	0.923	0.879	0.867	0.822	0.792	0.745
Methyl HT-SELEX, 1 experiments	median	0.923	0.879	0.867	0.822	0.772	0.745
Methyl HT-SELEX, 1 experiments	best	0.923	0.879	0.867	0.822	0.772	0.745
Non-Methyl HT-SELEX, 1 experiments	median	0.876	0.8	0.852	0.783	0.792	0.738
Non-Methyl HT-SELEX, 1 experiments	best	0.876	0.8	0.852	0.783	0.792	0.738

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.45	1.264	0.159	0.13

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZBTB7 {2.3.3.8} (TFClass)
TFClass ID	TFClass: 2.3.3.8.1
HGNC	HGNC:18078
MGI	MGI:1335091
EntrezGene (human)	GeneID:51341 (SSTAR profile)
EntrezGene (mouse)	GeneID:16969 (SSTAR profile)
UniProt ID (human)	ZBT7A_HUMAN
UniProt ID (mouse)	ZBT7A_MOUSE
UniProt AC (human)	O95365 (TFClass)
UniProt AC (mouse)	O88939 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZBT7A.H12INVITRO.0.P.B.pcm
PWM	ZBT7A.H12INVITRO.0.P.B.pwm
PFM	ZBT7A.H12INVITRO.0.P.B.pfm
Alignment	ZBT7A.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	ZBT7A.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	ZBT7A.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	ZBT7A.H12INVITRO.0.P.B_meme_format.meme
Transfac format	ZBT7A.H12INVITRO.0.P.B_transfac_format.txt
Homer format	ZBT7A.H12INVITRO.0.P.B_homer_format_0.001.txt ZBT7A.H12INVITRO.0.P.B_homer_format_0.0005.txt ZBT7A.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	218.0	192.0	499.0	92.0
02	355.0	11.0	622.0	13.0
03	6.0	1.0	945.0	49.0
04	7.0	0.0	992.0	2.0
05	0.0	6.0	986.0	9.0
06	9.0	0.0	55.0	937.0
07	9.0	984.0	1.0	7.0
08	5.0	310.0	162.0	524.0
09	19.0	586.0	120.0	276.0

PFM

	A	C	G	T
01	0.218	0.192	0.499	0.092
02	0.355	0.011	0.621	0.013
03	0.006	0.001	0.944	0.049
04	0.007	0.0	0.991	0.002
05	0.0	0.006	0.985	0.009
06	0.009	0.0	0.055	0.936
07	0.009	0.983	0.001	0.007
08	0.005	0.31	0.162	0.523
09	0.019	0.585	0.12	0.276

PWM

	A	C	G	T
01	-0.137	-0.263	0.687	-0.989
02	0.348	-2.986	0.906	-2.84
03	-3.485	-4.526	1.324	-1.603
04	-3.363	-4.983	1.372	-4.214
05	-4.983	-3.485	1.366	-3.157
06	-3.157	-4.983	-1.491	1.315
07	-3.157	1.364	-4.526	-3.363
08	-3.623	0.213	-0.431	0.735
09	-2.498	0.847	-0.728	0.097

Standard thresholds

P-value	Threshold
0.001	4.196375
0.0005	5.201275
0.0001	7.79464