ZBT7A.H12CORE.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT7A.H12CORE.1.SM.B
Gene (human)	ZBTB7A (GeneCards)
Gene synonyms (human)	FBI1, LRF, ZBTB7, ZNF857A
Gene (mouse)	Zbtb7a
Gene synonyms (mouse)	Lrf, Zbtb7
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	16
Consensus	ddddKdRGGGGTCKhv
GC content	66.99%
Information content (bits; total / per base)	14.06 / 0.879
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	833

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (61)	0.727	0.793	0.521	0.606	0.655	0.769	1.611	2.097	55.796	121.42

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.932	0.891	0.899	0.853	0.822	0.787
Overall, 2 experiments	best	0.937	0.898	0.9	0.855	0.834	0.794
Methyl HT-SELEX, 1 experiments	median	0.937	0.898	0.897	0.855	0.809	0.78
Methyl HT-SELEX, 1 experiments	best	0.937	0.898	0.897	0.855	0.809	0.78
Non-Methyl HT-SELEX, 1 experiments	median	0.928	0.883	0.9	0.852	0.834	0.794
Non-Methyl HT-SELEX, 1 experiments	best	0.928	0.883	0.9	0.852	0.834	0.794

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	1.531	0.266	0.133	0.097

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZBTB7 {2.3.3.8} (TFClass)
TFClass ID	TFClass: 2.3.3.8.1
HGNC	HGNC:18078
MGI	MGI:1335091
EntrezGene (human)	GeneID:51341 (SSTAR profile)
EntrezGene (mouse)	GeneID:16969 (SSTAR profile)
UniProt ID (human)	ZBT7A_HUMAN
UniProt ID (mouse)	ZBT7A_MOUSE
UniProt AC (human)	O95365 (TFClass)
UniProt AC (mouse)	O88939 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZBT7A.H12CORE.1.SM.B.pcm
PWM	ZBT7A.H12CORE.1.SM.B.pwm
PFM	ZBT7A.H12CORE.1.SM.B.pfm
Alignment	ZBT7A.H12CORE.1.SM.B.words.tsv
Threshold to P-value map	ZBT7A.H12CORE.1.SM.B.thr
Motif in other formats
JASPAR format	ZBT7A.H12CORE.1.SM.B_jaspar_format.txt
MEME format	ZBT7A.H12CORE.1.SM.B_meme_format.meme
Transfac format	ZBT7A.H12CORE.1.SM.B_transfac_format.txt
Homer format	ZBT7A.H12CORE.1.SM.B_homer_format_0.001.txt ZBT7A.H12CORE.1.SM.B_homer_format_0.0005.txt ZBT7A.H12CORE.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	179.0	89.0	317.0	248.0
02	138.5	88.5	350.5	255.5
03	104.0	75.0	490.0	164.0
04	158.0	92.0	440.0	143.0
05	100.0	47.0	536.0	150.0
06	144.0	80.0	433.0	176.0
07	204.0	9.0	584.0	36.0
08	89.0	2.0	737.0	5.0
09	0.0	0.0	580.0	253.0
10	0.0	0.0	833.0	0.0
11	0.0	0.0	833.0	0.0
12	0.0	0.0	11.0	822.0
13	2.0	824.0	0.0	7.0
14	21.0	33.0	447.0	332.0
15	150.25	403.25	61.25	218.25
16	170.25	190.25	343.25	129.25

PFM

	A	C	G	T
01	0.215	0.107	0.381	0.298
02	0.166	0.106	0.421	0.307
03	0.125	0.09	0.588	0.197
04	0.19	0.11	0.528	0.172
05	0.12	0.056	0.643	0.18
06	0.173	0.096	0.52	0.211
07	0.245	0.011	0.701	0.043
08	0.107	0.002	0.885	0.006
09	0.0	0.0	0.696	0.304
10	0.0	0.0	1.0	0.0
11	0.0	0.0	1.0	0.0
12	0.0	0.0	0.013	0.987
13	0.002	0.989	0.0	0.008
14	0.025	0.04	0.537	0.399
15	0.18	0.484	0.074	0.262
16	0.204	0.228	0.412	0.155

PWM

	A	C	G	T
01	-0.15	-0.839	0.417	0.173
02	-0.404	-0.845	0.517	0.203
03	-0.686	-1.007	0.851	-0.237
04	-0.274	-0.807	0.744	-0.372
05	-0.725	-1.461	0.94	-0.325
06	-0.365	-0.944	0.728	-0.167
07	-0.02	-2.978	1.026	-1.718
08	-0.839	-4.044	1.258	-3.447
09	-4.827	-4.827	1.019	0.193
10	-4.827	-4.827	1.38	-4.827
11	-4.827	-4.827	1.38	-4.827
12	-4.827	-4.827	-2.807	1.367
13	-4.044	1.369	-4.827	-3.186
14	-2.225	-1.801	0.76	0.463
15	-0.323	0.657	-1.205	0.047
16	-0.2	-0.09	0.497	-0.472

Standard thresholds

P-value	Threshold
0.001	2.92386
0.0005	4.22696
0.0001	6.97016