ZBT45.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT45.H12CORE.0.SM.B
Gene (human)	ZBTB45 (GeneCards)
Gene synonyms (human)	ZNF499
Gene (mouse)	Zbtb45
Gene synonyms (mouse)	Gm157, Zfp499
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	ddMMCCTATAKvn
GC content	46.11%
Information content (bits; total / per base)	13.526 / 1.04
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	7684

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.971	0.961	0.856	0.851	0.698	0.722
Overall, 2 experiments	best	0.982	0.974	0.887	0.88	0.718	0.743
Methyl HT-SELEX, 1 experiments	median	0.961	0.949	0.825	0.821	0.678	0.701
Methyl HT-SELEX, 1 experiments	best	0.961	0.949	0.825	0.821	0.678	0.701
Non-Methyl HT-SELEX, 1 experiments	median	0.982	0.974	0.887	0.88	0.718	0.743
Non-Methyl HT-SELEX, 1 experiments	best	0.982	0.974	0.887	0.88	0.718	0.743

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZBTB20-like {2.3.3.14} (TFClass)
TFClass ID	TFClass: 2.3.3.14.2
HGNC	HGNC:23715
MGI	MGI:2685003
EntrezGene (human)	GeneID:84878 (SSTAR profile)
EntrezGene (mouse)	GeneID:232879 (SSTAR profile)
UniProt ID (human)	ZBT45_HUMAN
UniProt ID (mouse)	ZBT45_MOUSE
UniProt AC (human)	Q96K62 (TFClass)
UniProt AC (mouse)	Q52KG4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	ZBT45.H12CORE.0.SM.B.pcm
PWM	ZBT45.H12CORE.0.SM.B.pwm
PFM	ZBT45.H12CORE.0.SM.B.pfm
Alignment	ZBT45.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	ZBT45.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	ZBT45.H12CORE.0.SM.B_jaspar_format.txt
MEME format	ZBT45.H12CORE.0.SM.B_meme_format.meme
Transfac format	ZBT45.H12CORE.0.SM.B_transfac_format.txt
Homer format	ZBT45.H12CORE.0.SM.B_homer_format_0.001.txt ZBT45.H12CORE.0.SM.B_homer_format_0.0005.txt ZBT45.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1815.25	1041.25	3167.25	1660.25
02	883.0	853.0	3360.0	2588.0
03	1320.0	5070.0	447.0	847.0
04	3872.0	2183.0	1518.0	111.0
05	11.0	7661.0	1.0	11.0
06	237.0	7207.0	217.0	23.0
07	0.0	0.0	0.0	7684.0
08	7683.0	0.0	0.0	1.0
09	2.0	1.0	0.0	7681.0
10	7015.0	0.0	669.0	0.0
11	24.0	767.0	4996.0	1897.0
12	3640.75	2132.75	1468.75	441.75
13	2206.0	1810.0	1495.0	2173.0

PFM

	A	C	G	T
01	0.236	0.136	0.412	0.216
02	0.115	0.111	0.437	0.337
03	0.172	0.66	0.058	0.11
04	0.504	0.284	0.198	0.014
05	0.001	0.997	0.0	0.001
06	0.031	0.938	0.028	0.003
07	0.0	0.0	0.0	1.0
08	1.0	0.0	0.0	0.0
09	0.0	0.0	0.0	1.0
10	0.913	0.0	0.087	0.0
11	0.003	0.1	0.65	0.247
12	0.474	0.278	0.191	0.057
13	0.287	0.236	0.195	0.283

PWM

	A	C	G	T
01	-0.057	-0.611	0.5	-0.146
02	-0.776	-0.81	0.559	0.298
03	-0.375	0.97	-1.454	-0.817
04	0.7	0.128	-0.235	-2.832
05	-4.979	1.382	-6.387	-4.979
06	-2.084	1.321	-2.172	-4.333
07	-6.757	-6.757	-6.757	1.385
08	1.385	-6.757	-6.757	-6.387
09	-6.118	-6.387	-6.757	1.385
10	1.294	-6.757	-1.053	-6.757
11	-4.295	-0.916	0.955	-0.013
12	0.639	0.104	-0.268	-1.466
13	0.138	-0.059	-0.25	0.123

Standard thresholds

P-value	Threshold
0.001	2.082615
0.0005	3.821565
0.0001	7.175025